PAPL

GENERAL INFORMATION

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Gene name

PAPL

Gene description

Iron/zinc purple acid phosphatase-like protein

Protein class

Enzymes
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (skin, tonsil)
GTEx:Group enriched (cerebellum, skin)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in a few tissues, mainly in a subset of neuronal cells, thyroid and adrenal gland.

ANTIBODY RELIABILITY

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Data reliability
description

Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Data reliability

Uncertain based on 2 antibodies.
HPA042005 , HPA042613
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (skin, tonsil)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (cerebellum, skin)

Organ

Expression



GENE INFORMATION

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Gene name

PAPL

Synonyms

Description

Iron/zinc purple acid phosphatase-like protein (UniProtKB/Swiss-Prot)

Entrez gene summary

Purple acid phosphatases (PAPs), including PAPL, are a family of binuclear metallohydrolases that have been identified in plants, animals, and fungi (Flanagan et al., 2006 [PubMed 16793224]).[supplied by OMIM, Mar 2008]

Chromosome

19

Cytoband

q13.2

Chromosome location (bp)

39083913 - 39111493

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000183760 (version 78.38)

Entrez gene

390928

UniProt

Q6ZNF0 (UniProt - Evidence at transcript level)

neXtProt

NX_Q6ZNF0

Antibodypedia

PAPL antibodies


PROTEIN BROWSER

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ENST00000331256
 
ENST00000594229
 
ENST00000601531
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PAPL-001 ENSP00000327557
ENST00000331256
Q6ZNF0
Show all »
Show » Show » 438 50.5 Yes 0
PAPL-003 ENSP00000470989
ENST00000594229
M0R045
Show all »
Show » Show » 334 36.6 Yes 0
PAPL-004 ENSP00000470089
ENST00000601531
Show » Show » 227 26.7 No 0