H2AFJ

GENERAL INFORMATION

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Gene name

H2AFJ

Gene description

H2A histone family, member J

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Caution, targets protein from more than one gene. Correlation with RNA expression data cannot be evaluated due to technical limitations (poly-A tail missing).

Data reliability

Supportive based on 1 antibody.
HPA041189
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

H2AFJ (HGNC Symbol)

Synonyms

FLJ10903, MGC921

Description

H2A histone family, member J (HGNC Symbol)

Entrez gene summary

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is located on chromosome 12 and encodes a variant H2A histone. The protein is divergent at the C-terminus compared to the consensus H2A histone family member. This gene also encodes an antimicrobial peptide with antibacterial and antifungal activity.[provided by RefSeq, Oct 2014]

Chromosome

12

Cytoband

p12.3

Chromosome location (bp)

14774383 - 14778002

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000246705 (version 78.38)

Entrez gene

55766

UniProt

Q9BTM1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BTM1

Antibodypedia

H2AFJ antibodies


PROTEIN BROWSER

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ENST00000544848
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

H2AFJ-001 ENSP00000438553
ENST00000544848
Q9BTM1
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