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HSPE1 gene information.

Gene data

Gene name:

HSPE1 (HGNC (curated))	Synonyms: CPN10, GROES
OTTHUMG00000132749 (Havana gene)

Description:

Heat shock 10kDa protein 1 (chaperonin 10)
Source acc: 5269 (HGNC Symbol)

Chromosome:

Cytoband:

q33.1

Chromosome location (bp):

198364718 - 198368181

Number of splice variants:

EnsEMBL ID:

ENSG00000115541

EnsEMBL version:

57.37

Stanford source search:

Search for "HSPE1"

NCBI gene ID:

3336

NCBI gene summary:

This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. [provided by RefSeq]

Gene ontology:

GO:0005524 [ATP binding]
GO:0005737 [cytoplasm]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0006457 [protein folding]
GO:0006919 [activation of caspase activity]
GO:0006986 [response to unfolded protein]
GO:0051082 [unfolded protein binding]
GO:0051087 [chaperone binding]

Protein data - 3 matching of 3 transcripts


Protein EnsEMBL ID:	ENSP00000387101
Transcript EnsEMBL ID:	ENST00000409729
Transcript display name:	HSPE1-002
Uniprot ID:	B8ZZ54 (Target identity: 100%; Query identity: 100%)
Number of amino acids:	47
Molecular weight:	5 kDa
Protein class:	N/A
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Protein EnsEMBL ID:	ENSP00000386447
Transcript EnsEMBL ID:	ENST00000409468
Transcript display name:	HSPE1-004
Uniprot ID:	B8ZZL8 (Target identity: 100%; Query identity: 100%)
Number of amino acids:	101
Molecular weight:	11 kDa
Protein class:	N/A
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Protein EnsEMBL ID:	ENSP00000233893
Transcript EnsEMBL ID:	ENST00000233893
Transcript display name:	HSPE1-001
Uniprot ID:	P61604 (EnsEMBL direct mapping)
Number of amino acids:	102
Molecular weight:	11 kDa
Protein class:	Candidate cancer biomarkers Cb
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Validation Summary

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