BETA
CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Not detected
Glial cells: Not detected
Neuronal cells: Low
Neuropil: High
RNA expressioni
Consensus:561.2 nTPM
HPA:259.1 nTPM
HPA Brain:457.9 nTPM
HPA PFC Brain:306.7 nTPM
GTEx:561.2 nTPM
FANTOM5:720.3 Scaled Tags Per Million
Macaque:572.7 nTPM
Mouse:711.4 nTPM
Rat:308.4 nTPM
Pig:285.5 nTPM
CEREBRAL CORTEX - SINGLE NUCLEI RNA EXPRESSIONi

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NEURONSi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 290
c-1 Excitatory (VGLUT1) CUX2+
c-2 Inhibitory (GAD1/2) LHX6+ T...
c-3 Inhibitory (GAD1/2) CXCL14+...
c-4 Inhibitory (GAD1/2) LHX6+ T...
c-5 Inhibitory (GAD1/2) CXCL14+
c-6 Excitatory (VGLUT1) FOXP2+
c-7 Excitatory (VGLUT1) CUX2+
c-8 Excitatory (VGLUT1)
c-9 Inhibitory (GAD1/2) LHX6+ T...
c-10 Inhibitory (GAD1/2) CXCL14+...
c-11 Inhibitory (GAD1/2) CXCL14+...
c-12 Excitatory (VGLUT1) FOXP2+
c-13 Excitatory (VGLUT1) FOXP2+
c-14 Excitatory (VGLUT1) CUX2+
c-15 Excitatory (VGLUT1) FOXP2+
c-16 Inhibitory (GAD1/2) CXCL14+...
c-17 Excitatory (VGLUT1/2)
c-18 Excitatory (VGLUT1) FOXP2+
c-19 Excitatory (VGLUT1/2) CUX2+
c-20 Inhibitory (GAD1/2) LAMP5+ ...
c-21 Excitatory (VGLUT1) FOXP2+
c-22 Inhibitory (GAD1/2) CXCL14+
c-23 Excitatory (VGLUT1) FOXP2+
c-24 Excitatory (VGLUT1) SOX5+
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NON-NEURONALi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 130
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Oligodendrocyte progenitor ...
c-4 Oligodendrocytes
c-5 Astrocytes
c-6 Astrocytes
c-7 Microglia
c-8 Oligodendrocyte progenitor ...
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Astrocytes
c-12 Astrocytes
c-13 Astrocytes
c-14 Microglia
c-15 Vascular endothelial cells
c-16 Fibroblasts
c-17 Oligodendrocytes (CNTN1+)
c-18 Macrophages
c-19 Immature oligodendrocytes
c-20 Oligodendrocyte progenitor ...
c-21 Pericytes
c-22 Lymphocytes
c-23 Fibroblasts
c-24 Vascular smooth muscle cell
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA027296Antibody HPA054276Antibody CAB047333
Endothelial cells Not detectedLowLow
Glial cells Not detectedLowNot detected
Neuronal cells LowLowMedium
Neuropil HighMediumMedium






CEREBRAL CORTEX - PROTEINTALKS DB MS
Median intensity 559522
Sample Intensity
Cerebral cortex_01
 442602
Cerebral cortex_02
 421104
Cerebral cortex_03
 590190
Cerebral cortex_04
 568730
Cerebral cortex_05
 627109
Cerebral cortex_06
 461258
Cerebral cortex_07
 417959
Cerebral cortex_08
 548301
Cerebral cortex_09
 443511
Cerebral cortex_10
 598951
Cerebral cortex_11
 451533
Cerebral cortex_12
 567979
Cerebral cortex_13
 463682
Cerebral cortex_14
 501080
Cerebral cortex_15
 625810
Cerebral cortex_16
 621538
Cerebral cortex_17
 561628
Cerebral cortex_18
 521625
Cerebral cortex_19
 669744
Cerebral cortex_20
 691224
Cerebral cortex_21
 800440
Cerebral cortex_22
 740888
Cerebral cortex_23
 482095
Cerebral cortex_24
 574310
Cerebral cortex_25
 542758
Cerebral cortex_26
 697928
Cerebral cortex_27
 598944
Cerebral cortex_28
 425338
Cerebral cortex_29
 366646
Cerebral cortex_30
 606651
Cerebral cortex_31
 505783
Cerebral cortex_32
 711926
Cerebral cortex_33
 274610
Cerebral cortex_34
 506039
Cerebral cortex_35
 519540
Cerebral cortex_36
 596589
Cerebral cortex_37
 557417
Cerebral cortex_38
 706550

CEREBRAL CORTEX - MANN MS
Median intensity 752840585
Replicate Intensity
Cerebral cortex_01
 745492407
Cerebral cortex_02
 752840585
Cerebral cortex_03
 841769357

CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 259.1
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 318
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 137.6
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 321.6
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain Stereo-seq

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 457.9
Sample id Sample description nTPM
Angular gyrus
nTPM: 298.4
2221 Female, age 67, right hemisphere 646.9
2103 Male, age 75, left hemisphere 333.4
2260 Female, age 72, left hemisphere 314.9
1866 Male, age 76, both hemispheres 310.5
2602 Female, age 94, right hemisphere 248.7
1790 Male, age 76, right hemisphere 248.1
2722 Male, age 61, left hemisphere 160.1
2265 Female, age 91, left hemisphere 125.0
Angular gyrus (white matter)
nTPM: 187.4
1920 Male, age 76, both hemispheres 187.4
Anterior cingulate cortex, supragenual-dorsal
nTPM: 257.4
1896 Female, age 85, right hemisphere 322.9
2547 Male, age 74, left hemisphere 305.9
2472 Male, age 75, left hemisphere 291.0
2342 Female, age 94, right hemisphere 187.9
2478 Female, age 67, right hemisphere 179.5
Anterior cingulate cortex, supragenual-ventral
nTPM: 206.6
1761 Male, age 74, left hemisphere 254.4
1950 Female, age 85, right hemisphere 222.6
2538 Male, age 75, left hemisphere 217.5
1755 Female, age 94, right hemisphere 204.8
2479 Female, age 67, right hemisphere 133.9
Anterior insular cortex, dorsal
nTPM: 211.8
2506 Female, age 94, right hemisphere 311.7
2670 Male, age 75, left hemisphere 207.6
2001 Male, age 76, right hemisphere 184.2
2235 Female, age 91, right hemisphere 143.7
Anterior insular cortex, ventral
nTPM: 289.7
1925 Female, age 91, left hemisphere 423.6
2507 Female, age 94, left hemisphere 297.0
2757 Male, age 61, right hemisphere 293.5
2262 Female, age 67, right hemisphere 282.2
1852 Male, age 76, left hemisphere 231.0
2596 Male, age 75, left hemisphere 210.7
Area parastriata, inferior
nTPM: 204.5
1789 Male, age 76, right hemisphere 245.0
2268 Male, age 61, right hemisphere 235.2
1760 Female, age 67, left hemisphere 231.5
2509 Female, age 94, left hemisphere 206.1
1758 Female, age 72, right hemisphere 196.4
2234 Male, age 75, left hemisphere 194.8
2421 Female, age 91, left hemisphere 122.3
Area parastriata, parietal
nTPM: 208.3
2420 Male, age 75, left hemisphere 236.8
2680 Female, age 94, right hemisphere 225.1
1785 Male, age 76, right hemisphere 221.8
2233 Male, age 61, right hemisphere 185.8
2236 Female, age 91, left hemisphere 171.7
Area parastriata, superior
nTPM: 250.1
2419 Male, age 75, right hemisphere 327.6
2881 Male, age 76, left hemisphere 317.5
1773 Female, age 91, left hemisphere 311.4
2604 Female, age 94, right hemisphere 218.7
2435 Male, age 61, left hemisphere 166.7
2684 Female, age 67, left hemisphere 159.0
Area parastriata, temporal
nTPM: 258.0
2471 Male, age 75, left hemisphere 307.8
2424 Female, age 67, left hemisphere 300.4
1804 Male, age 76, right hemisphere 244.8
2681 Female, age 94, right hemisphere 219.9
2267 Male, age 61, right hemisphere 216.9
Area striata
nTPM: 213.2
1753 Female, age 72, right hemisphere 269.8
2427 Female, age 91, left hemisphere 247.5
2417 Male, age 61, right hemisphere 237.7
2679 Female, age 94, right hemisphere 219.4
1884 Male, age 76, left hemisphere 160.5
2002 Female, age 91, right hemisphere 144.1
Area striata (white matter)
nTPM: 190.4
2258 Female, age 91, left hemisphere 190.4
Claustrum
nTPM: 199.0
2392 Female, age 94, both hemispheres 256.5
2491 Male, age 75, both hemispheres 246.4
2198 Male, age 80, both hemispheres 227.4
2284 Female, age 91, both hemispheres 222.7
1956 Male, age 74, unknown 191.5
2568 Male, age 61, both hemispheres 185.0
2196 Female, age 79, unknown 174.1
2645 Female, age 72, unknown 161.9
2292 Female, age 85, both hemispheres 125.4
Corpus callosum, genu (white matter)
nTPM: 151.4
1885 Female, age 94, left hemisphere 233.7
2771 Male, age 75, left hemisphere 203.7
1886 Female, age 67, right hemisphere 170.0
1934 Male, age 61, right hemisphere 111.3
1849 Female, age 91, right hemisphere 106.9
1887 Male, age 76, left hemisphere 82.6
Corpus callosum, splenium (white matter)
nTPM: 155.2
2104 Male, age 75, left hemisphere 193.0
2238 Female, age 94, right hemisphere 177.4
2847 Female, age 67, right hemisphere 174.3
1946 Male, age 76, left hemisphere 76.0
Frontal eye field
nTPM: 304.4
2543 Male, age 74, left hemisphere 360.9
2147 Male, age 61, left hemisphere 298.0
2441 Male, age 75, left hemisphere 282.1
2761 Female, age 94, left hemisphere 276.6
Frontal operculum
nTPM: 257.0
2348 Male, age 75, left hemisphere 299.3
2030 Male, age 61, right hemisphere 264.7
2781 Female, age 85, right hemisphere 207.1
Fusiform gyrus
nTPM: 256.6
2074 Female, age 91, left hemisphere 304.9
2112 Male, age 80, both hemispheres 282.3
1807 Male, age 76, left hemisphere 271.9
2784 Female, age 85, left hemisphere 255.8
2433 Female, age 72, left hemisphere 244.3
2431 Male, age 75, right hemisphere 219.5
2617 Female, age 94, left hemisphere 217.8
Inferior frontal gyrus, opercular
nTPM: 278.8
2866 Male, age 61, right hemisphere 365.1
2865 Male, age 61, left hemisphere 314.0
2872 Female, age 94, right hemisphere 305.7
2871 Female, age 94, left hemisphere 302.2
2869 Male, age 74, left hemisphere 289.2
2868 Male, age 75, right hemisphere 277.2
2867 Male, age 75, left hemisphere 271.8
2875 Female, age 67, left hemisphere 238.3
2873 Female, age 85, left hemisphere 231.2
2874 Female, age 85, right hemisphere 193.1
Inferior parietal lobule
nTPM: 256.4
2418 Male, age 75, left hemisphere 416.8
2599 Female, age 94, left hemisphere 238.2
2876 Male, age 76, right hemisphere 190.9
2606 Female, age 67, right hemisphere 179.7
Inferior temporal gyrus
nTPM: 275.3
1965 Female, age 91, left hemisphere 340.3
1880 Male, age 80, right hemisphere 327.4
2430 Male, age 75, right hemisphere 287.3
1808 Male, age 76, left hemisphere 248.9
2689 Female, age 94, right hemisphere 224.7
1970 Female, age 85, right hemisphere 223.1
Intraparietal deep sulcus
nTPM: 221.6
2230 Male, age 61, right hemisphere 303.4
2798 Male, age 76, left hemisphere 255.2
2102 Female, age 91, left hemisphere 234.0
2669 Male, age 75, left hemisphere 201.0
2600 Female, age 94, right hemisphere 185.0
2607 Female, age 67, right hemisphere 151.2
Lingual gyrus
nTPM: 235.0
2838 Male, age 80, right hemisphere 294.9
2688 Male, age 75, right hemisphere 233.8
2618 Female, age 94, left hemisphere 227.7
1893 Male, age 76, left hemisphere 218.6
2073 Female, age 85, left hemisphere 199.6
Middle cingulate cortex
nTPM: 226.0
2357 Female, age 67, right hemisphere 358.1
2028 Female, age 85, left hemisphere 226.6
2539 Male, age 75, left hemisphere 185.5
2640 Female, age 94, right hemisphere 184.2
2633 Male, age 74, left hemisphere 175.4
Middle temporal gyrus
nTPM: 258.7
2034 Female, age 91, right hemisphere 332.4
1819 Male, age 80, right hemisphere 304.2
1799 Male, age 76, left hemisphere 238.1
2616 Female, age 94, left hemisphere 218.7
2611 Male, age 75, right hemisphere 200.0
Occipital cortex
nTPM: 306.9
2426 Male, age 75, midline 420.9
2470 Male, age 75, right hemisphere 339.3
1842 Male, age 76, right hemisphere 289.4
2608 Female, age 67, both hemispheres 285.1
2677 Female, age 67, right hemisphere 199.9
Occipital cortex (white matter)
nTPM: 240.9
2259 Male, age 75, midline 256.7
2257 Female, age 67, both hemispheres 225.2
Olfactory area
nTPM: 322.5
2756 Female, age 67, right hemisphere 446.3
2222 Female, age 67, right hemisphere 440.8
2352 Female, age 94, right hemisphere 333.4
2440 Male, age 75, left hemisphere 270.4
1805 Female, age 85, right hemisphere 265.6
2542 Male, age 74, left hemisphere 178.8
Olfactory tubercle
nTPM: 292.9
1998 Female, age 91, both hemispheres 403.5
1846 Male, age 80, right hemisphere 273.8
2487 Female, age 94, left hemisphere 263.7
2856 Male, age 75, right hemisphere 230.6
Orbitofrontal gyrus, anterior
nTPM: 134.0
2863 Female, age 85, right hemisphere 207.4
2864 Female, age 67, left hemisphere 112.6
2862 Female, age 85, left hemisphere 82.1
Paracentral lobule, anterior
nTPM: 344.2
1926 Male, age 61, left hemisphere 433.5
2474 Male, age 74, left hemisphere 398.0
2340 Female, age 67, right hemisphere 396.3
1754 Male, age 75, left hemisphere 321.4
1776 Female, age 85, right hemisphere 259.0
2638 Female, age 94, right hemisphere 257.1
Paracentral lobule, posterior
nTPM: 242.3
1775 Female, age 85, right hemisphere 295.6
2551 Female, age 94, right hemisphere 260.3
1764 Male, age 74, right hemisphere 255.3
2345 Male, age 61, left hemisphere 212.6
2446 Male, age 75, left hemisphere 187.6
Parahippocampal cortex (white matter)
nTPM: 235.3
2157 Female, age 91, both hemispheres 235.3
Parietal operculum
nTPM: 261.8
2356 Female, age 67, right hemisphere 337.1
1763 Male, age 74, left hemisphere 242.5
2552 Female, age 94, right hemisphere 242.5
2719 Male, age 75, left hemisphere 225.2
Parieto-insular cortex
nTPM: 281.9
1976 Female, age 91, right hemisphere 535.1
2232 Male, age 61, right hemisphere 232.3
2671 Male, age 75, left hemisphere 224.7
2831 Male, age 76, right hemisphere 215.2
2508 Female, age 94, right hemisphere 202.2
Parieto-occipital transitional area
nTPM: 223.0
2468 Male, age 75, left hemisphere 272.3
1784 Male, age 76, right hemisphere 267.8
2270 Male, age 61, right hemisphere 228.2
2674 Female, age 94, right hemisphere 227.9
2683 Female, age 67, left hemisphere 118.5
Parieto-temporal junction (white matter)
nTPM: 144.8
1935 Female, age 94, right hemisphere 285.1
1999 Female, age 67, right hemisphere 157.1
2469 Male, age 75, right hemisphere 147.2
2774 Male, age 61, right hemisphere 106.0
2770 Female, age 91, right hemisphere 101.7
2121 Male, age 76, left hemisphere 71.8
Piriform cortex
nTPM: 170.4
2347 Male, age 75, right hemisphere 232.0
2153 Female, age 85, left hemisphere 108.7
Postcentral gyrus
nTPM: 457.9
2533 Male, age 75, right hemisphere 457.9
Postcentral gyrus, dorsal
nTPM: 328.9
1836 Female, age 85, right hemisphere 411.4
2151 Male, age 61, left hemisphere 362.5
2339 Female, age 67, right hemisphere 341.6
2477 Female, age 94, right hemisphere 307.2
2544 Male, age 74, left hemisphere 280.4
2350 Male, age 75, left hemisphere 269.9
Postcentral gyrus, middle
nTPM: 354.3
2146 Female, age 67, right hemisphere 517.5
2248 Male, age 61, left hemisphere 374.1
1897 Female, age 85, right hemisphere 326.6
2444 Male, age 75, left hemisphere 318.3
2545 Male, age 74, left hemisphere 234.7
Postcentral gyrus, ventral
nTPM: 275.5
2445 Male, age 75, left hemisphere 375.3
2836 Female, age 94, right hemisphere 234.6
2024 Female, age 85, right hemisphere 216.7
Posterior cingulate cortex
nTPM: 274.0
2553 Female, age 94, right hemisphere 304.7
1759 Male, age 74, right hemisphere 300.5
2473 Male, age 75, left hemisphere 216.7
Posterior cingulate cortex, dorsal
nTPM: 186.7
2641 Female, age 94, right hemisphere 266.6
2076 Female, age 85, right hemisphere 204.2
2540 Male, age 75, right hemisphere 179.8
2343 Male, age 61, left hemisphere 172.6
2634 Male, age 74, left hemisphere 171.0
2556 Female, age 67, right hemisphere 126.1
Posterior cingulate cortex, ventral
nTPM: 210.6
1994 Female, age 85, right hemisphere 244.7
1762 Female, age 94, right hemisphere 224.0
2346 Male, age 61, left hemisphere 213.3
2635 Male, age 74, left hemisphere 207.0
2448 Female, age 67, right hemisphere 188.6
2541 Male, age 75, right hemisphere 186.0
Posterior insular cortex
nTPM: 263.5
2832 Female, age 91, right hemisphere 331.4
2511 Female, age 67, right hemisphere 266.5
2603 Female, age 94, left hemisphere 259.8
2597 Male, age 75, left hemisphere 258.6
1823 Male, age 76, right hemisphere 241.0
2231 Male, age 61, left hemisphere 223.4
Precentral gyrus
nTPM: 280.4
2557 Male, age 75, right hemisphere 280.4
Precentral gyrus, dorsal
nTPM: 320.8
2354 Female, age 67, right hemisphere 386.6
2476 Female, age 94, right hemisphere 337.8
1756 Male, age 74, left hemisphere 307.4
2442 Male, age 75, left hemisphere 251.3
Precentral gyrus, middle
nTPM: 412.9
1969 Female, age 67, right hemisphere 735.9
1909 Male, age 61, left hemisphere 477.6
2443 Male, age 75, left hemisphere 307.1
2549 Female, age 94, right hemisphere 274.6
2475 Male, age 74, right hemisphere 269.6
Precentral gyrus, ventral
nTPM: 322.6
2662 Female, age 67, right hemisphere 424.5
2678 Male, age 74, left hemisphere 360.1
2630 Male, age 75, left hemisphere 257.5
2550 Female, age 94, right hemisphere 248.5
Precuneus
nTPM: 197.5
1782 Male, age 76, right hemisphere 253.4
2467 Male, age 75, right hemisphere 220.1
2673 Female, age 94, right hemisphere 210.7
1780 Female, age 91, right hemisphere 188.5
2510 Female, age 67, right hemisphere 166.9
2594 Male, age 61, left hemisphere 145.5
Premotor cortex, dorsal
nTPM: 273.7
2027 Male, age 61, left hemisphere 366.6
1878 Female, age 85, right hemisphere 341.1
2631 Male, age 74, left hemisphere 247.4
2536 Male, age 75, left hemisphere 215.4
2554 Female, age 67, right hemisphere 197.9
Premotor cortex, ventral
nTPM: 303.2
1777 Female, age 67, left hemisphere 516.3
1881 Female, age 85, right hemisphere 342.5
2349 Male, age 75, left hemisphere 257.6
1779 Male, age 61, left hemisphere 255.0
2637 Female, age 94, right hemisphere 254.8
1757 Male, age 74, left hemisphere 192.9
Retrosplenial cortex
nTPM: 245.8
1951 Male, age 61, right hemisphere 379.9
1914 Male, age 76, right hemisphere 189.1
2675 Female, age 94, left hemisphere 168.6
Somatomor cortex, precentral gyrus (white matter)
nTPM: 254.6
2439 Male, age 75, right hemisphere 254.6
Somatosensory cortex, postcentral gyrus, ventral (white matter)
nTPM: 265.5
2623 Male, age 75, right hemisphere 265.5
Subcentral gyrus, S2
nTPM: 269.6
2351 Male, age 75, left hemisphere 348.1
2762 Male, age 74, left hemisphere 310.6
2072 Male, age 61, left hemisphere 281.9
2839 Female, age 94, right hemisphere 245.4
1964 Female, age 85, right hemisphere 242.1
2555 Female, age 67, right hemisphere 189.5
Superior parietal lobule
nTPM: 276.6
1992 Female, age 91, right hemisphere 451.5
1800 Male, age 76, right hemisphere 310.1
2229 Male, age 61, right hemisphere 249.3
2672 Female, age 94, right hemisphere 215.1
2605 Female, age 67, right hemisphere 157.2
Superior temporal gyrus
nTPM: 305.5
1844 Female, age 91, left hemisphere 480.4
2615 Female, age 94, left hemisphere 330.7
1843 Male, age 76, left hemisphere 253.4
2025 Male, age 80, right hemisphere 232.3
2687 Male, age 75, right hemisphere 230.9
Supplementary motor cortex
nTPM: 308.6
1993 Male, age 61, left hemisphere 415.3
2537 Male, age 75, left hemisphere 348.0
2548 Female, age 94, right hemisphere 246.5
2632 Male, age 74, left hemisphere 224.6
Supramarginal gyrus
nTPM: 243.4
1991 Female, age 91, right hemisphere 316.6
1798 Male, age 76, right hemisphere 245.8
2601 Female, age 94, left hemisphere 222.6
2415 Male, age 61, left hemisphere 220.7
2513 Female, age 72, left hemisphere 211.1
Temporal pole
nTPM: 291.5
1832 Female, age 91, left hemisphere 458.4
1853 Female, age 85, right hemisphere 309.2
2518 Male, age 75, right hemisphere 252.4
2612 Female, age 94, left hemisphere 249.3
1826 Male, age 76, right hemisphere 188.2
Temporal white matter
nTPM: 117.2
2523 Female, age 94, left hemisphere 168.9
2254 Male, age 75, right hemisphere 165.1
2736 Female, age 91, right hemisphere 140.5
1801 Male, age 76, left hemisphere 64.5
2524 Female, age 85, left hemisphere 46.8
Temporo-insular cortex, parainsular gyrus
nTPM: 192.3
2598 Male, age 75, left hemisphere 226.0
2416 Male, age 61, right hemisphere 203.6
2676 Female, age 94, right hemisphere 200.4
1802 Male, age 76, left hemisphere 195.0
2512 Female, age 67, right hemisphere 190.6
2264 Female, age 91, right hemisphere 138.3
Temporo-occipital transitional zone
nTPM: 273.6
1793 Male, age 80, right hemisphere 355.1
1900 Male, age 76, left hemisphere 310.3
2251 Female, age 85, right hemisphere 155.6
Transversal temporal gyrus, anterior
nTPM: 331.8
1888 Female, age 91, left hemisphere 449.3
1910 Male, age 80, right hemisphere 369.4
2522 Female, age 94, left hemisphere 334.1
2610 Male, age 75, right hemisphere 266.8
1809 Male, age 76, right hemisphere 239.4
Transversal temporal gyrus, posterior
nTPM: 271.5
2833 Male, age 80, right hemisphere 337.0
1967 Female, age 91, right hemisphere 300.8
2614 Female, age 94, left hemisphere 245.1
2520 Male, age 75, right hemisphere 238.3
1922 Male, age 76, left hemisphere 236.3

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 306.7
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 142.1
1516 Female, age 85, left hemisphere 298.2
1511 Male, age 61, right hemisphere 230.3
1510 Male, age 61, left hemisphere 214.3
1518 Female, age 67, right hemisphere 106.4
1515 Female, age 94, right hemisphere 91.7
1512 Male, age 75, left hemisphere 90.0
1517 Female, age 67, left hemisphere 89.3
1514 Male, age 74, right hemisphere 81.9
1513 Male, age 74, left hemisphere 76.6
Anterior cingulate gyrus, pregenual-ventral
nTPM: 125.9
1519 Male, age 61, left hemisphere 194.5
1523 Female, age 67, left hemisphere 153.7
1520 Male, age 75, right hemisphere 114.1
1522 Male, age 74, right hemisphere 88.7
1521 Male, age 74, left hemisphere 78.4
Anterior cingulate gyrus, subgenual
nTPM: 151.0
1529 Female, age 85, left hemisphere 426.5
1524 Male, age 61, left hemisphere 180.1
1530 Female, age 67, right hemisphere 123.6
1526 Male, age 75, right hemisphere 87.3
1525 Male, age 75, left hemisphere 82.9
1528 Male, age 74, right hemisphere 78.6
1527 Male, age 74, left hemisphere 78.1
Dorsolateral prefrontal cortex
nTPM: 165.7
1449 Female, age 85, right hemisphere 337.5
1444 Male, age 75, left hemisphere 198.9
1445 Male, age 75, right hemisphere 139.0
1447 Female, age 94, left hemisphere 132.9
1450 Female, age 67, right hemisphere 128.4
1448 Female, age 94, right hemisphere 115.0
1446 Male, age 74, right hemisphere 108.2
Dorsomedial prefrontal cortex
nTPM: 184.6
1439 Male, age 61, left hemisphere 366.2
1440 Male, age 61, right hemisphere 282.5
1441 Male, age 75, left hemisphere 107.2
1443 Female, age 67, right hemisphere 88.9
1442 Male, age 75, right hemisphere 78.3
Frontomarginal cortex
nTPM: 273.3
1471 Female, age 85, left hemisphere 874.6
1466 Male, age 61, right hemisphere 400.0
1465 Male, age 61, left hemisphere 358.5
1467 Male, age 75, right hemisphere 226.2
1470 Female, age 94, right hemisphere 152.3
1469 Female, age 94, left hemisphere 130.9
1468 Male, age 74, left hemisphere 120.9
1473 Female, age 67, right hemisphere 118.6
1472 Female, age 67, left hemisphere 77.4
Frontopolar cortex
nTPM: 225.3
1459 Male, age 61, right hemisphere 452.2
1458 Male, age 61, left hemisphere 337.4
1461 Male, age 75, right hemisphere 248.1
1460 Male, age 75, left hemisphere 172.1
1462 Female, age 94, left hemisphere 145.1
1464 Female, age 67, right hemisphere 125.5
1463 Female, age 67, left hemisphere 96.9
Gyrus rectus
nTPM: 218.5
1480 Female, age 85, left hemisphere 469.3
1475 Male, age 61, right hemisphere 428.8
1474 Male, age 61, left hemisphere 222.2
1476 Male, age 75, left hemisphere 145.1
1478 Female, age 94, left hemisphere 138.2
1479 Female, age 94, right hemisphere 131.6
1477 Male, age 75, right hemisphere 114.9
1481 Female, age 67, left hemisphere 97.6
Inferior frontal gyrus, orbital
nTPM: 189.6
1501 Male, age 61, right hemisphere 540.4
1508 Female, age 85, right hemisphere 414.1
1500 Male, age 61, left hemisphere 288.6
1502 Male, age 75, left hemisphere 117.4
1506 Female, age 94, left hemisphere 116.0
1505 Male, age 74, right hemisphere 99.7
1504 Male, age 74, left hemisphere 92.3
1509 Female, age 67, right hemisphere 90.4
1503 Male, age 75, right hemisphere 85.1
1507 Female, age 85, left hemisphere 52.0
Inferior frontal gyrus, triangular
nTPM: 183.8
1548 Female, age 85, right hemisphere 391.2
1542 Male, age 61, left hemisphere 272.7
1543 Male, age 61, right hemisphere 227.2
1549 Female, age 67, left hemisphere 174.7
1547 Female, age 85, left hemisphere 133.6
1546 Female, age 94, right hemisphere 109.8
1544 Male, age 75, right hemisphere 85.4
1545 Male, age 74, right hemisphere 75.8
Orbitofrontal gyrus, lateral
nTPM: 186.4
1498 Female, age 85, right hemisphere 447.3
1493 Male, age 61, right hemisphere 372.1
1494 Male, age 75, left hemisphere 119.0
1495 Female, age 94, left hemisphere 97.3
1497 Female, age 85, left hemisphere 96.6
1496 Female, age 94, right hemisphere 87.6
1499 Female, age 67, right hemisphere 84.6
Orbitofrontal gyrus, medial
nTPM: 157.2
1490 Female, age 85, right hemisphere 373.6
1489 Female, age 85, left hemisphere 285.1
1482 Male, age 61, left hemisphere 243.4
1483 Male, age 75, left hemisphere 111.7
1487 Female, age 94, left hemisphere 111.1
1484 Male, age 75, right hemisphere 110.0
1488 Female, age 94, right hemisphere 107.0
1492 Female, age 67, right hemisphere 103.2
1485 Male, age 74, left hemisphere 102.3
1491 Female, age 67, left hemisphere 97.2
1486 Male, age 74, right hemisphere 84.6
Orbitofrontal gyrus, posterior
nTPM: 170.8
1531 Male, age 61, left hemisphere 345.9
1532 Male, age 61, right hemisphere 321.7
1539 Female, age 85, right hemisphere 257.7
1538 Female, age 85, left hemisphere 242.0
1533 Male, age 75, left hemisphere 156.2
1536 Female, age 94, left hemisphere 127.4
1537 Female, age 94, right hemisphere 96.4
1541 Female, age 67, right hemisphere 91.6
1534 Male, age 75, right hemisphere 88.3
1540 Female, age 67, left hemisphere 83.8
1535 Male, age 74, left hemisphere 67.7
Subcallosal gyrus
nTPM: 172.3
1559 Female, age 85, right hemisphere 443.3
1558 Female, age 85, left hemisphere 441.7
1550 Male, age 61, left hemisphere 271.2
1551 Male, age 61, right hemisphere 217.2
1561 Female, age 67, right hemisphere 127.9
1557 Female, age 94, right hemisphere 98.4
1554 Male, age 74, left hemisphere 88.1
1556 Female, age 94, left hemisphere 81.9
1555 Male, age 74, right hemisphere 78.0
1560 Female, age 67, left hemisphere 77.2
1553 Male, age 75, right hemisphere 76.6
1552 Male, age 75, left hemisphere 66.7
Superior frontal gyrus
nTPM: 227.2
1569 Female, age 85, left hemisphere 570.5
1570 Female, age 85, right hemisphere 449.9
1562 Male, age 61, left hemisphere 345.2
1563 Male, age 61, right hemisphere 303.9
1567 Female, age 94, left hemisphere 130.3
1565 Male, age 75, right hemisphere 118.0
1564 Male, age 75, left hemisphere 113.1
1568 Female, age 94, right hemisphere 105.4
1566 Male, age 74, right hemisphere 70.2
1571 Female, age 67, right hemisphere 66.0
Temporal cortex
nTPM: 152.4
1596 Female, age 85, right hemisphere 396.5
1590 Male, age 61, right hemisphere 232.5
1594 Female, age 94, left hemisphere 119.3
1591 Male, age 75, right hemisphere 87.3
1595 Female, age 94, right hemisphere 82.0
1593 Male, age 74, right hemisphere 76.6
1592 Male, age 74, left hemisphere 72.7
Ventrolateral prefrontal cortex
nTPM: 145.1
1455 Female, age 85, right hemisphere 342.9
1453 Male, age 74, right hemisphere 138.0
1454 Female, age 94, left hemisphere 122.7
1457 Female, age 67, right hemisphere 112.5
1451 Male, age 75, right hemisphere 108.0
1452 Male, age 74, left hemisphere 99.0
1456 Female, age 67, left hemisphere 92.4
Ventromedial prefrontal cortex
nTPM: 306.7
1436 Female, age 85, left hemisphere 730.7
1432 Male, age 61, left hemisphere 388.2
1437 Female, age 85, right hemisphere 364.6
1433 Male, age 61, right hemisphere 340.4
1435 Female, age 94, right hemisphere 127.0
1434 Male, age 75, right hemisphere 115.5
1438 Female, age 67, left hemisphere 80.9

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 561.2
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 409.5
Samples: 233

Max nTPM: 964.5
Min nTPM: 100.1
Std nTPM: 199.6
Median nTPM: 400.3
GTEX-12WSI-0011-R3a-SM-GJ3QB 50-59 years, male 964.5
GTEX-T2IS-0011-R3A-SM-32QPB 20-29 years, female 878.7
GTEX-11DYG-0011-R3b-SM-GI4X7 60-69 years, male 876.0
GTEX-YFC4-0011-R3a-SM-4RGLP 40-49 years, female 872.9
GTEX-N7MS-0011-R3a-SM-33HC6 60-69 years, male 832.0
GTEX-QVUS-0011-R3A-SM-3GAFD 60-69 years, female 831.7
GTEX-RNOR-0011-R3A-SM-5SI8E 50-59 years, female 810.7
GTEX-12126-0011-R3b-SM-GJ3RE 20-29 years, male 807.1
GTEX-12ZZY-0011-R3a-SM-GJ3Q6 60-69 years, male 802.8
GTEX-14JIY-0011-R3a-SM-5YYAQ 60-69 years, male 789.9
GTEX-WL46-0011-R3A-SM-3TW8E 50-59 years, male 789.0
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Brain - Cortex
Average nTPM: 431.9
Samples: 270

Max nTPM: 865.3
Min nTPM: 104.1
Std nTPM: 149.1
Median nTPM: 441.9
GTEX-1B933-3126-SM-7P8RL 50-59 years, female 865.3
GTEX-PVOW-2526-SM-2XCF7 40-49 years, male 857.4
GTEX-T2IS-3026-SM-32QPM 20-29 years, female 797.7
GTEX-1HT8W-3026-SM-CGQEO 30-39 years, male 744.7
GTEX-TSE9-3026-SM-3DB76 60-69 years, female 717.3
GTEX-1C6WA-3026-SM-7P8RQ 60-69 years, male 715.9
GTEX-1EMGI-3026-SM-7P8P6 60-69 years, male 713.7
GTEX-WVLH-3026-SM-3MJG9 50-59 years, male 701.8
GTEX-1HCVE-3026-SM-CL54G 50-59 years, male 678.4
GTEX-15EO6-3026-SM-7KUMA 50-59 years, male 676.8
GTEX-WL46-2926-SM-3LK82 50-59 years, male 676.3
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Brain - Frontal Cortex (BA9)
Average nTPM: 561.2
Samples: 269

Max nTPM: 1094.3
Min nTPM: 83.0
Std nTPM: 215.5
Median nTPM: 584.7
GTEX-1QMI2-0011-R10a-SM-F3428 60-69 years, male 1094.3
GTEX-1B8L1-0011-R10b-SM-7P8Q4 60-69 years, male 1091.5
GTEX-12WSC-0011-R10a-SM-5GU57 50-59 years, male 1026.1
GTEX-PVOW-0011-R10A-SM-EXOHB 40-49 years, male 1024.0
GTEX-1QP6S-0011-R10a-SM-F341V 40-49 years, male 991.9
GTEX-1B8SF-0011-R10b-SM-7P8SW 60-69 years, male 981.9
GTEX-111FC-0011-R10a-SM-GIN8G 60-69 years, male 944.6
GTEX-13RTJ-0011-R10b-SM-5O9CW 60-69 years, male 917.0
GTEX-11DXY-0011-R10b-SM-DO12C 60-69 years, male 912.4
GTEX-1GF9V-0011-R10b-SM-CKZNP 60-69 years, male 908.2
GTEX-1EX96-0011-R10b-SM-CE6QR 50-59 years, male 904.5
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 720.3
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 172.6
FF:10163-103B1 76 years, female 172.6
Postcentral gyrus
Scaled Tags Per Million: 720.3
FF:10032-101E5 44-52 years, mixed 720.3
Frontal lobe
Scaled Tags Per Million: 624.1
FF:10040-101F4 32-61 years, mixed 624.1
Insula
Scaled Tags Per Million: 580.7
FF:10039-101F3 20-68 years, mixed 580.7
Medial frontal gyrus
Scaled Tags Per Million: 324.3
FF:10150-102I6 76 years, female 324.3
Medial temporal gyrus
Scaled Tags Per Million: 523.9
FF:10183-103D3 60 years, female 793.8
FF:10156-103A3 76 years, female 254.0
Occipital lobe
Scaled Tags Per Million: 708.9
FF:10076-102A4 27 years, male 708.9
Occipital pole
Scaled Tags Per Million: 570.6
FF:10036-101E9 22-68 years, mixed 570.6
Paracentral gyrus
Scaled Tags Per Million: 699.0
FF:10035-101E8 22-69 years, mixed 699.0
Parietal lobe
Scaled Tags Per Million: 543.7
FF:10171-103B9 60 years, female 644.0
FF:10034-101E7 35-89 years, mixed 624.5
FF:10157-103A4 76 years, female 362.5
Temporal lobe
Scaled Tags Per Million: 524.5
FF:10031-101E4 32-61 years, mixed 524.5

CEREBRAL CORTEX - Macaque RNA-seq
Max subtype nTPMi 572.7
Macaque sample Sample description nTPM
Angular gyrus
nTPM: 572.7
Samples: 1

Max nTPM: 572.7
Min nTPM: 572.7
Sample A 572.7
Claustrum
nTPM: 427.4
Samples: 1

Max nTPM: 427.4
Min nTPM: 427.4
Sample B 427.4
Fusiform gyrus
nTPM: 430.0
Samples: 2

Max nTPM: 432.9
Min nTPM: 427.2
Sample A 432.9
Sample B 427.2
Inferior temporal gyrus
nTPM: 413.9
Samples: 2

Max nTPM: 530.9
Min nTPM: 296.9
Sample A 296.9
Sample B 530.9
Middle temporal gyrus
nTPM: 473.5
Samples: 2

Max nTPM: 474.7
Min nTPM: 472.4
Sample A 472.4
Sample B 474.7
Postcentral gyrus
nTPM: 483.8
Samples: 2

Max nTPM: 565.8
Min nTPM: 401.9
Sample A 401.9
Sample B 565.8
Posterior cingulate cortex
nTPM: 401.4
Samples: 2

Max nTPM: 432.8
Min nTPM: 370.0
Sample A 370.0
Sample B 432.8
Precentral gyrus
nTPM: 505.3
Samples: 3

Max nTPM: 604.6
Min nTPM: 416.5
Sample A 416.5
Sample B 604.6
Sample C 494.7
Superior parietal lobule
nTPM: 432.2
Samples: 2

Max nTPM: 470.5
Min nTPM: 393.8
Sample A 393.8
Sample B 470.5
Superior temporal gyrus
nTPM: 417.9
Samples: 2

Max nTPM: 423.7
Min nTPM: 412.0
Sample A 412.0
Sample B 423.7
Supramarginal gyrus
nTPM: 482.2
Samples: 2

Max nTPM: 504.0
Min nTPM: 460.4
Sample A 460.4
Sample B 504.0
Gyrus rectus
nTPM: 395.3
Samples: 2

Max nTPM: 417.6
Min nTPM: 372.9
Sample A 417.6
Sample B 372.9
Insular cortex
nTPM: 408.5
Samples: 2

Max nTPM: 430.7
Min nTPM: 386.2
Sample A 430.7
Sample B 386.2
Superior frontal gyrus
nTPM: 485.5
Samples: 2

Max nTPM: 577.6
Min nTPM: 393.3
Sample A 393.3
Sample B 577.6

CEREBRAL CORTEX - Pig RNA-seqi
Max subtype nTPMi 285.5
Pig sample Sample description nTPM
Occipital cortex
nTPM: 263.3
Samples: 4

Max nTPM: 305.1
Min nTPM: 206.1
Sample A Female 275.8
Sample B Female 305.1
Sample C Male 266.3
Sample D Male 206.1
Retrosplenial cortex
nTPM: 200.8
Samples: 4

Max nTPM: 238.4
Min nTPM: 175.7
Sample A Female 209.2
Sample B Female 180.1
Sample C Male 238.4
Sample D Male 175.7
Cingulate cortex
nTPM: 226.5
Samples: 4

Max nTPM: 299.9
Min nTPM: 159.2
Sample A Female 299.9
Sample B Female 159.2
Sample C Male 265.4
Sample D Male 181.5
Insular cortex
nTPM: 160.1
Samples: 4

Max nTPM: 229.6
Min nTPM: 113.0
Sample A Female 229.6
Sample B Female 113.0
Sample C Male 170.8
Sample D Male 126.8
Motor cortex
nTPM: 231.4
Samples: 4

Max nTPM: 279.2
Min nTPM: 183.9
Sample A Female 249.0
Sample B Female 183.9
Sample C Male 279.2
Sample D Male 213.6
Prefrontal cortex
nTPM: 221.0
Samples: 4

Max nTPM: 254.9
Min nTPM: 185.2
Sample A Female 254.9
Sample B Female 232.0
Sample C Male 212.0
Sample D Male 185.2
Somatosensory cortex
nTPM: 285.5
Samples: 3

Max nTPM: 322.1
Min nTPM: 239.1
Sample B Female 239.1
Sample C Male 295.4
Sample D Male 322.1
Temporal cortex
nTPM: 196.9
Samples: 3

Max nTPM: 219.9
Min nTPM: 164.7
Sample A Female 206.2
Sample B Female 164.7
Sample D Male 219.9

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 711.4
Mouse sample Sample description nTPM
Motor and prefrontal cortex
nTPM: 672.9
Samples: 4

Max nTPM: 731.4
Min nTPM: 535.6
Sample A 731.4
Sample B 708.0
Sample C 716.8
Sample D 535.6
Retrosplenial and cingulate cortex
nTPM: 711.4
Samples: 3

Max nTPM: 767.7
Min nTPM: 681.1
Sample A 685.4
Sample B 767.7
Sample C 681.1
Somatosensory cortex
nTPM: 695.5
Samples: 4

Max nTPM: 763.5
Min nTPM: 648.0
Sample A 720.7
Sample B 649.9
Sample C 763.5
Sample D 648.0
Visual cortex
nTPM: 638.0
Samples: 4

Max nTPM: 706.8
Min nTPM: 543.5
Sample A 706.8
Sample B 543.5
Sample C 650.7
Sample D 650.9

CEREBRAL CORTEX - Rat RNA-seq
Max subtype nTPMi 308.4
Rat sample Sample description nTPM
Occipital cortex
nTPM: 296.2
Samples: 4

Max nTPM: 315.4
Min nTPM: 267.4
Sample A 303.4
Sample A 267.4
Sample A 315.4
Sample A 298.6
Retrosplenial and cingulate cortex
nTPM: 268.6
Samples: 4

Max nTPM: 280.3
Min nTPM: 257.4
Sample A 280.3
Sample A 266.2
Sample B 270.5
Sample A 257.4
Somatosensory cortex
nTPM: 308.4
Samples: 4

Max nTPM: 323.2
Min nTPM: 291.8
Sample A 309.8
Sample A 323.2
Sample A 308.6
Sample A 291.8

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