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BETA
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  • MDH1
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:270.7 nTPM
HPA Brain:238.4 nTPM
GTEx:270.7 nTPM
FANTOM5:112.2 Scaled Tags Per Million
Macaque:413.7 nTPM
Mouse:649.5 nTPM
Rat:255.6 nTPM
Pig:277.2 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 520
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 130
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

238.4
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 166.9
2019 Male, age 18, unknown 284.8
2411 Female, age 72, unknown 229.2
1827 Male, age 72, unknown 189.3
2219 Male, age 76, both hemispheres 178.9
1870 Female, age 42, unknown 145.4
1833 Male, age 53, unknown 144.1
2828 Female, age 72, unknown 138.9
1830 Male, age 51, unknown 133.3
2666 Male, age 74, left hemisphere 127.0
2586 Male, age 75, left hemisphere 98.3
Dorsal raphe nucleus
nTPM: 189.3
2298 Female, age 72, unknown 249.4
1828 Male, age 53, unknown 214.7
2047 Male, age 72, unknown 184.5
2750 Male, age 76, both hemispheres 169.1
2016 Female, age 72, unknown 128.9
Inferior colliculus
nTPM: 200.6
2097 Female, age 72, unknown 284.0
1890 Male, age 53, unknown 215.7
1848 Female, age 42, unknown 178.7
2849 Male, age 72, unknown 124.0
Median raphe nucleus
nTPM: 184.0
2220 Male, age 76, midline 184.0
Periaquaductal grey, anterior
nTPM: 157.7
2502 Female, age 75, unknown 168.9
1947 Male, age 18, unknown 158.0
1795 Male, age 51, unknown 146.1
Periaquaductal grey, dorsal
nTPM: 141.8
1831 Male, age 72, unknown 156.6
2464 Female, age 72, unknown 151.5
1840 Male, age 53, unknown 146.9
2850 Male, age 76, both hemispheres 112.4
Periaquaductal grey, lateral
nTPM: 144.0
2272 Male, age 74, both hemispheres 191.7
2053 Male, age 18, unknown 127.6
2140 Male, age 76, both hemispheres 112.9
Pretectal area
nTPM: 228.1
2007 Male, age 72, unknown 341.1
1817 Female, age 42, unknown 322.2
1944 Female, age 72, unknown 315.3
1816 Male, age 51, unknown 305.1
1815 Male, age 53, unknown 237.7
2667 Female, age 75, unknown 214.8
2273 Male, age 74, both hemispheres 211.0
2224 Female, age 72, unknown 180.8
2316 Male, age 76, right hemisphere 137.0
2407 Male, age 75, both hemispheres 122.3
2825 Male, age 18, unknown 121.9
Red nucleus
nTPM: 176.6
1821 Female, age 72, unknown 270.1
2785 Male, age 18, unknown 242.9
2725 Female, age 75, unknown 199.0
1954 Female, age 42, unknown 182.4
2823 Male, age 76, right hemisphere 173.2
1865 Male, age 51, unknown 169.9
1904 Male, age 53, unknown 156.2
2769 Male, age 72, unknown 154.4
2227 Male, age 72, unknown 152.4
2503 Female, age 72, unknown 150.6
2588 Male, age 74, left hemisphere 135.5
2584 Male, age 75, left hemisphere 132.3
Substantia nigra
nTPM: 238.4
1916 Female, age 42, unknown 357.0
1889 Female, age 72, unknown 302.5
2241 Male, age 72, unknown 275.6
1851 Male, age 51, unknown 271.5
1941 Male, age 53, unknown 268.8
2409 Female, age 72, unknown 250.9
2665 Male, age 74, both hemispheres 189.2
2590 Female, age 75, unknown 168.8
2699 Male, age 18, unknown 162.2
2583 Male, age 75, right hemisphere 137.0
Superior colliculus
nTPM: 168.0
2087 Female, age 72, unknown 265.5
1895 Male, age 76, right hemisphere 214.0
2668 Female, age 75, unknown 177.0
2261 Male, age 18, unknown 174.9
1796 Male, age 53, unknown 170.7
2587 Male, age 74, left hemisphere 166.3
1839 Male, age 51, unknown 145.4
1913 Female, age 42, unknown 133.1
1995 Male, age 72, unknown 125.3
2664 Male, age 75, both hemispheres 107.4
Ventral tegmental area
nTPM: 202.4
2410 Female, age 72, unknown 289.5
1915 Female, age 42, unknown 245.9
2218 Male, age 76, both hemispheres 242.6
1942 Male, age 51, unknown 166.8
2223 Female, age 72, unknown 143.6
2021 Male, age 53, unknown 126.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

270.7
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 270.7
Samples: 183

Max nTPM: 1156.1
Min nTPM: 66.5
Std nTPM: 197.9
Median nTPM: 193.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 1156.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 1016.2
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 941.3
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 925.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 877.1
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 849.6
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 793.7
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 721.4
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 717.1
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 627.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 604.0
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 592.5
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 582.0
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 554.4
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 551.7
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 535.4
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 531.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 521.2
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 519.0
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 518.6
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 515.6
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 514.7
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 512.6
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 507.8
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 493.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 484.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 475.9
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 468.6
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 466.1
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 464.9
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 460.8
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 460.2
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 455.1
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 450.7
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 447.2
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 445.5
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 422.2
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 419.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 405.0
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 402.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 397.1
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 391.0
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 372.2
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 360.0
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 348.0
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 337.7
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 337.7
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 334.2
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 328.3
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 328.1
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 323.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 310.2
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 309.4
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 306.9
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 304.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 300.4
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 298.5
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 294.1
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 291.1
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 290.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 273.8
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 270.3
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 266.0
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 253.3
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 253.0
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 249.3
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 243.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 240.4
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 238.8
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 236.0
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 235.6
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 233.2
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 232.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 227.7
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 219.2
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 218.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 218.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 217.9
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 210.1
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 208.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 208.4
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 206.1
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 204.0
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 201.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 201.8
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 200.3
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 198.7
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 197.4
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 196.2
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 196.0
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 194.7
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 193.1
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 192.5
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 188.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 188.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 187.8
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 187.7
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 185.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 183.9
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 181.9
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 179.7
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 176.9
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 170.6
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 170.3
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 168.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 167.4
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 165.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 163.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 162.9
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 162.2
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 161.5
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 159.4
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 159.0
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 158.7
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 158.4
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 157.8
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 157.0
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 156.8
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 156.5
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 154.9
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 153.4
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 152.8
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 150.8
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 150.5
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 150.1
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 149.6
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 148.0
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 143.5
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 142.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 141.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 140.9
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 139.3
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 138.9
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 138.6
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 137.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 136.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 136.3
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 136.3
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 135.8
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 135.3
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 134.2
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 133.7
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 132.0
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 129.9
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 129.6
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 128.6
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 127.7
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 124.4
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 124.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 123.7
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 123.7
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 123.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 122.0
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 121.7
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 121.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 121.1
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 120.6
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 120.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 117.9
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 117.9
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 116.6
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 115.8
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 114.9
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 113.8
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 112.3
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 112.0
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 109.6
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 106.8
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 106.7
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 106.7
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 106.2
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 105.8
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 105.2
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 104.5
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 101.2
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 97.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 94.5
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 89.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 88.3
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 81.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 79.0
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 72.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 66.5
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

112.2
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 112.2
FF:10158-103A5 76 years, female 112.2

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

413.7
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 404.8
Samples: 1

Max nTPM: 404.8
Min nTPM: 404.8
Sample A 404.8
Midbrain
nTPM: 300.4
Samples: 1

Max nTPM: 300.4
Min nTPM: 300.4
Sample A 300.4
Superior colliculi
nTPM: 413.7
Samples: 1

Max nTPM: 413.7
Min nTPM: 413.7
Sample A 413.7

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

277.2
Pig sample Sample description nTPM
Substantia nigra
nTPM: 230.2
Samples: 3

Max nTPM: 307.0
Min nTPM: 153.2
Sample A Female 307.0
Sample B Female 153.2
Sample C Male 230.5
Midbrain
nTPM: 223.1
Samples: 3

Max nTPM: 255.9
Min nTPM: 173.0
Sample B Female 173.0
Sample C Male 255.9
Sample D Male 240.4
Periaqueductal gray
nTPM: 144.4
Samples: 3

Max nTPM: 163.6
Min nTPM: 120.6
Sample B Female 149.1
Sample C Male 163.6
Sample D Male 120.6
Superior colliculi
nTPM: 277.2
Samples: 4

Max nTPM: 359.3
Min nTPM: 206.4
Sample A Female 314.2
Sample B Female 206.4
Sample C Male 359.3
Sample D Male 228.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

649.5
Mouse sample Sample description nTPM
Midbrain
nTPM: 649.5
Samples: 4

Max nTPM: 670.2
Min nTPM: 614.3
Sample A 670.2
Sample B 614.3
Sample C 660.5
Sample D 653.1

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

255.6
Rat sample Sample description nTPM
Midbrain
nTPM: 255.6
Samples: 4

Max nTPM: 263.6
Min nTPM: 244.0
Sample A 262.0
Sample A 252.7
Sample A 263.6
Sample A 244.0

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