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  • YPEL3
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:123.5 nTPM
HPA Brain:169.8 nTPM
GTEx:123.5 nTPM
FANTOM5:232.4 Scaled Tags Per Million
Macaque:249.9 nTPM
Mouse:194.4 nTPM
Rat:182.0 nTPM
Pig:169.3 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 290
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 140
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

169.8
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 157.3
2586 Male, age 75, left hemisphere 200.5
2219 Male, age 76, both hemispheres 183.0
1827 Male, age 72, unknown 175.0
2828 Female, age 72, unknown 165.0
2666 Male, age 74, left hemisphere 151.3
1870 Female, age 42, unknown 143.2
1830 Male, age 51, unknown 141.2
2019 Male, age 18, unknown 138.7
1833 Male, age 53, unknown 138.5
2411 Female, age 72, unknown 136.5
Dorsal raphe nucleus
nTPM: 120.1
2047 Male, age 72, unknown 128.0
2750 Male, age 76, both hemispheres 127.4
2298 Female, age 72, unknown 122.0
1828 Male, age 53, unknown 115.9
2016 Female, age 72, unknown 107.2
Inferior colliculus
nTPM: 158.8
2849 Male, age 72, unknown 188.0
1848 Female, age 42, unknown 173.2
2097 Female, age 72, unknown 143.8
1890 Male, age 53, unknown 130.2
Median raphe nucleus
nTPM: 132.6
2220 Male, age 76, midline 132.6
Periaquaductal grey, anterior
nTPM: 169.3
1947 Male, age 18, unknown 174.1
2502 Female, age 75, unknown 171.1
1795 Male, age 51, unknown 162.7
Periaquaductal grey, dorsal
nTPM: 129.5
1840 Male, age 53, unknown 143.8
2464 Female, age 72, unknown 133.1
2850 Male, age 76, both hemispheres 121.0
1831 Male, age 72, unknown 120.3
Periaquaductal grey, lateral
nTPM: 128.5
2053 Male, age 18, unknown 135.4
2140 Male, age 76, both hemispheres 126.2
2272 Male, age 74, both hemispheres 123.9
Pretectal area
nTPM: 169.8
2007 Male, age 72, unknown 215.3
1816 Male, age 51, unknown 211.2
1817 Female, age 42, unknown 201.0
1944 Female, age 72, unknown 190.6
2667 Female, age 75, unknown 184.6
1815 Male, age 53, unknown 182.3
2407 Male, age 75, both hemispheres 152.3
2825 Male, age 18, unknown 148.8
2316 Male, age 76, right hemisphere 133.1
2224 Female, age 72, unknown 127.0
2273 Male, age 74, both hemispheres 121.5
Red nucleus
nTPM: 138.2
2785 Male, age 18, unknown 164.1
2584 Male, age 75, left hemisphere 156.8
2588 Male, age 74, left hemisphere 152.0
2503 Female, age 72, unknown 139.3
1821 Female, age 72, unknown 139.0
2769 Male, age 72, unknown 137.0
1865 Male, age 51, unknown 136.8
2227 Male, age 72, unknown 131.7
1904 Male, age 53, unknown 129.9
1954 Female, age 42, unknown 127.6
2725 Female, age 75, unknown 123.8
2823 Male, age 76, right hemisphere 120.9
Substantia nigra
nTPM: 148.6
1941 Male, age 53, unknown 194.6
2665 Male, age 74, both hemispheres 190.9
1889 Female, age 72, unknown 181.1
2583 Male, age 75, right hemisphere 144.2
1851 Male, age 51, unknown 143.3
1916 Female, age 42, unknown 135.3
2699 Male, age 18, unknown 134.2
2409 Female, age 72, unknown 133.8
2590 Female, age 75, unknown 125.9
2241 Male, age 72, unknown 103.1
Superior colliculus
nTPM: 162.1
2668 Female, age 75, unknown 185.9
1796 Male, age 53, unknown 175.5
2261 Male, age 18, unknown 171.0
1895 Male, age 76, right hemisphere 166.9
2664 Male, age 75, both hemispheres 166.4
2087 Female, age 72, unknown 163.8
1839 Male, age 51, unknown 156.3
1913 Female, age 42, unknown 152.5
2587 Male, age 74, left hemisphere 144.2
1995 Male, age 72, unknown 139.0
Ventral tegmental area
nTPM: 130.0
2410 Female, age 72, unknown 150.0
1915 Female, age 42, unknown 134.4
2218 Male, age 76, both hemispheres 134.2
2223 Female, age 72, unknown 128.1
1942 Male, age 51, unknown 124.1
2021 Male, age 53, unknown 109.2

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

123.5
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 123.5
Samples: 183

Max nTPM: 351.8
Min nTPM: 20.7
Std nTPM: 40.6
Median nTPM: 118.3
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 351.8
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 262.6
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 242.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 208.7
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 204.8
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 203.8
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 200.1
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 195.5
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 188.5
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 185.3
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 183.2
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 182.9
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 182.2
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 179.2
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 178.6
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 177.8
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 177.7
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 176.9
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 176.3
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 172.9
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 172.4
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 172.3
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 171.5
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 171.0
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 167.4
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 162.8
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 161.1
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 159.2
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 158.5
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 158.1
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 157.0
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 154.3
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 153.8
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 153.5
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 152.7
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 151.2
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 150.6
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 150.5
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 149.0
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 148.6
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 148.4
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 147.4
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 147.4
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 147.1
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 146.4
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 144.6
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 144.5
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 144.4
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 142.7
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 141.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 141.6
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 140.8
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 139.3
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 139.2
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 137.8
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 137.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 135.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 134.0
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 133.4
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 133.2
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 132.7
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 132.6
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 130.8
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 130.5
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 130.4
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 129.9
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 128.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 128.8
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 128.0
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 128.0
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 127.6
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 126.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 126.0
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 125.9
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 123.3
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 122.2
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 121.9
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 121.7
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 121.3
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 121.1
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 121.0
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 120.9
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 120.1
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 119.5
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 119.5
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 119.4
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 119.4
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 119.3
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 119.1
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 119.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 118.5
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 118.3
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 118.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 117.6
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 117.3
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 117.2
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 115.8
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 115.7
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 115.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 115.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 115.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 115.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 115.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 114.1
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 114.0
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 113.4
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 113.3
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 113.0
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 112.9
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 112.4
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 112.2
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 112.2
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 110.7
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 110.5
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 110.1
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 109.9
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 109.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 108.8
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 108.6
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 108.0
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 107.5
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 107.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 106.4
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 105.8
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 105.8
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 105.4
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 105.3
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 105.3
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 105.1
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 104.9
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 104.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 104.0
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 103.8
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 103.1
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 102.4
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 100.9
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 100.9
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 99.8
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 97.5
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 97.0
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 95.2
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 95.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 94.6
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 93.4
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 93.1
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 92.8
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 92.8
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 92.6
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 91.1
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 90.2
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 89.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 88.7
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 88.4
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 88.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 87.2
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 86.3
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 86.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 85.0
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 84.8
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 84.1
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 83.9
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 83.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 82.9
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 81.9
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 80.9
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 80.4
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 80.2
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 76.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 74.3
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 74.2
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 71.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 71.0
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 69.8
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 66.0
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 65.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 62.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 60.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 59.9
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 57.5
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 54.9
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 43.8
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 42.7
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 20.7
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

232.4
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 232.4
FF:10158-103A5 76 years, female 232.4

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

249.9
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 135.2
Samples: 1

Max nTPM: 135.2
Min nTPM: 135.2
Sample A 135.2
Midbrain
nTPM: 176.2
Samples: 1

Max nTPM: 176.2
Min nTPM: 176.2
Sample A 176.2
Superior colliculi
nTPM: 249.9
Samples: 1

Max nTPM: 249.9
Min nTPM: 249.9
Sample A 249.9

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

169.3
Pig sample Sample description nTPM
Substantia nigra
nTPM: 132.2
Samples: 3

Max nTPM: 165.2
Min nTPM: 97.6
Sample A Female 165.2
Sample B Female 97.6
Sample C Male 133.8
Midbrain
nTPM: 166.1
Samples: 3

Max nTPM: 219.3
Min nTPM: 108.9
Sample B Female 108.9
Sample C Male 219.3
Sample D Male 170.0
Periaqueductal gray
nTPM: 122.4
Samples: 3

Max nTPM: 136.0
Min nTPM: 108.5
Sample B Female 108.5
Sample C Male 136.0
Sample D Male 122.8
Superior colliculi
nTPM: 169.2
Samples: 4

Max nTPM: 202.1
Min nTPM: 120.4
Sample A Female 181.2
Sample B Female 120.4
Sample C Male 202.1
Sample D Male 173.2

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

194.4
Mouse sample Sample description nTPM
Midbrain
nTPM: 194.4
Samples: 4

Max nTPM: 213.0
Min nTPM: 184.7
Sample A 184.7
Sample B 213.0
Sample C 192.7
Sample D 187.0

MIDBRAIN - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

182.0
Rat sample Sample description nTPM
Midbrain
nTPM: 182.0
Samples: 4

Max nTPM: 193.0
Min nTPM: 157.3
Sample A 187.3
Sample A 193.0
Sample A 190.5
Sample A 157.3

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