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BETA
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  • CIRBP
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
Brain proteome
Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:239.1 nTPM
HPA Brain:193.1 nTPM
GTEx:239.1 nTPM
FANTOM5:264.8 Scaled Tags Per Million
Macaque:92.6 nTPM
Mouse:62.2 nTPM
Pig:174.8 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 220
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 400
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - Annotated protein expression
Pending normal tissue analysis

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

193.1
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 189.8
2586 Male, age 75, left hemisphere 217.0
1827 Male, age 72, unknown 210.4
1870 Female, age 42, unknown 197.3
2828 Female, age 72, unknown 192.6
2411 Female, age 72, unknown 191.3
2219 Male, age 76, both hemispheres 187.5
1833 Male, age 53, unknown 183.3
1830 Male, age 51, unknown 176.8
2019 Male, age 18, unknown 174.8
2666 Male, age 74, left hemisphere 166.6
Dorsal raphe nucleus
nTPM: 175.5
2750 Male, age 76, both hemispheres 183.8
2016 Female, age 72, unknown 180.9
2298 Female, age 72, unknown 176.9
2047 Male, age 72, unknown 170.6
1828 Male, age 53, unknown 165.5
Inferior colliculus
nTPM: 184.3
1890 Male, age 53, unknown 190.2
2849 Male, age 72, unknown 188.7
2097 Female, age 72, unknown 184.5
1848 Female, age 42, unknown 173.8
Median raphe nucleus
nTPM: 181.5
2220 Male, age 76, midline 181.5
Periaquaductal grey, anterior
nTPM: 193.1
2502 Female, age 75, unknown 209.5
1795 Male, age 51, unknown 185.5
1947 Male, age 18, unknown 184.4
Periaquaductal grey, dorsal
nTPM: 187.3
1840 Male, age 53, unknown 208.9
1831 Male, age 72, unknown 185.6
2850 Male, age 76, both hemispheres 177.9
2464 Female, age 72, unknown 176.8
Periaquaductal grey, lateral
nTPM: 192.5
2053 Male, age 18, unknown 206.1
2272 Male, age 74, both hemispheres 187.1
2140 Male, age 76, both hemispheres 184.3
Pretectal area
nTPM: 189.7
2667 Female, age 75, unknown 207.8
2825 Male, age 18, unknown 206.0
1815 Male, age 53, unknown 195.3
2273 Male, age 74, both hemispheres 194.8
2007 Male, age 72, unknown 189.4
1817 Female, age 42, unknown 188.4
2407 Male, age 75, both hemispheres 187.2
2316 Male, age 76, right hemisphere 185.9
2224 Female, age 72, unknown 183.6
1816 Male, age 51, unknown 181.7
1944 Female, age 72, unknown 166.8
Red nucleus
nTPM: 189.8
2584 Male, age 75, left hemisphere 221.1
2503 Female, age 72, unknown 219.3
2588 Male, age 74, left hemisphere 215.0
1865 Male, age 51, unknown 194.8
1904 Male, age 53, unknown 186.3
1821 Female, age 72, unknown 182.7
2227 Male, age 72, unknown 182.3
2769 Male, age 72, unknown 181.7
2823 Male, age 76, right hemisphere 181.1
2725 Female, age 75, unknown 178.6
2785 Male, age 18, unknown 168.7
1954 Female, age 42, unknown 165.7
Substantia nigra
nTPM: 182.1
2590 Female, age 75, unknown 200.3
1851 Male, age 51, unknown 197.6
2583 Male, age 75, right hemisphere 193.5
2665 Male, age 74, both hemispheres 188.9
1916 Female, age 42, unknown 183.8
2699 Male, age 18, unknown 183.5
2409 Female, age 72, unknown 182.0
1889 Female, age 72, unknown 171.1
2241 Male, age 72, unknown 167.5
1941 Male, age 53, unknown 152.6
Superior colliculus
nTPM: 190.1
2664 Male, age 75, both hemispheres 241.2
2261 Male, age 18, unknown 202.9
1995 Male, age 72, unknown 200.3
1913 Female, age 42, unknown 195.5
1796 Male, age 53, unknown 194.9
1895 Male, age 76, right hemisphere 192.9
1839 Male, age 51, unknown 178.3
2087 Female, age 72, unknown 172.9
2587 Male, age 74, left hemisphere 170.1
2668 Female, age 75, unknown 151.8
Ventral tegmental area
nTPM: 179.2
1942 Male, age 51, unknown 195.8
2021 Male, age 53, unknown 192.0
1915 Female, age 42, unknown 182.2
2223 Female, age 72, unknown 174.1
2410 Female, age 72, unknown 167.9
2218 Male, age 76, both hemispheres 163.5

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

239.1
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 239.1
Samples: 183

Max nTPM: 628.3
Min nTPM: 68.0
Std nTPM: 77.6
Median nTPM: 231.9
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 628.3
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 501.0
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 494.0
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 420.2
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 409.9
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 403.5
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 403.4
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 371.7
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 363.4
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 349.3
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 347.1
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 344.8
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 341.4
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 336.7
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 332.6
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 329.0
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 329.0
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 328.4
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 327.8
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 327.5
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 327.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 319.2
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 318.2
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 314.2
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 312.7
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 312.0
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 309.7
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 301.2
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 301.0
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 299.1
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 298.6
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 297.1
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 296.9
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 296.7
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 296.6
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 295.9
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 294.9
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 289.1
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 287.6
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 285.3
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 284.2
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 283.0
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 282.9
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 282.4
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 282.3
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 278.7
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 276.6
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 276.1
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 274.6
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 272.2
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 271.4
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 270.2
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 270.2
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 268.8
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 268.3
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 268.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 265.7
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 264.2
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 264.0
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 261.6
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 261.4
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 260.3
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 259.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 259.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 258.6
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 253.2
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 252.1
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 251.5
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 251.1
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 250.2
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 248.8
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 247.8
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 243.9
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 242.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 242.4
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 241.9
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 239.4
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 238.4
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 237.7
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 237.4
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 236.9
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 236.2
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 236.2
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 236.1
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 235.6
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 235.0
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 234.7
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 233.1
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 233.0
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 232.4
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 232.0
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 231.9
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 231.8
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 231.1
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 230.3
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 230.2
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 229.8
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 229.7
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 229.0
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 228.9
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 228.8
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 228.7
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 228.1
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 227.3
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 226.6
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 225.7
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 225.4
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 223.9
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 223.5
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 221.7
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 221.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 220.2
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 220.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 219.8
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 218.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 217.9
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 216.6
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 215.8
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 214.9
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 213.6
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 213.0
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 212.9
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 212.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 212.0
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 211.7
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 211.4
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 210.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 209.4
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 207.9
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 207.6
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 207.0
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 206.3
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 205.5
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 205.3
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 203.6
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 201.9
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 201.5
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 200.3
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 200.2
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 198.3
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 197.5
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 194.7
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 193.6
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 193.1
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 192.7
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 191.3
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 190.4
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 189.7
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 188.7
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 186.3
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 184.0
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 182.0
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 180.6
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 180.5
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 174.8
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 173.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 172.1
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 170.5
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 164.4
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 161.7
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 161.6
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 159.8
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 142.4
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 142.3
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 139.1
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 138.4
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 138.4
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 137.9
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 127.6
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 122.5
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 121.8
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 118.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 116.8
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 110.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 109.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 105.4
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 102.2
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 95.7
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 89.6
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 87.7
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 71.7
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 71.0
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 68.0
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

264.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 264.8
FF:10158-103A5 76 years, female 264.8

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

92.6
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 92.6
Samples: 1

Max nTPM: 92.6
Min nTPM: 92.6
Sample A 92.6
Midbrain
nTPM: 76.6
Samples: 1

Max nTPM: 76.6
Min nTPM: 76.6
Sample A 76.6
Superior colliculi
nTPM: 76.6
Samples: 1

Max nTPM: 76.6
Min nTPM: 76.6
Sample A 76.6

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

174.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 174.8
Samples: 3

Max nTPM: 192.4
Min nTPM: 154.3
Sample A Female 154.3
Sample B Female 192.4
Sample C Male 177.7
Midbrain
nTPM: 164.5
Samples: 3

Max nTPM: 186.8
Min nTPM: 146.3
Sample B Female 186.8
Sample C Male 160.3
Sample D Male 146.3
Periaqueductal gray
nTPM: 169.8
Samples: 3

Max nTPM: 183.5
Min nTPM: 159.0
Sample B Female 183.5
Sample C Male 167.0
Sample D Male 159.0
Superior colliculi
nTPM: 170.7
Samples: 4

Max nTPM: 189.5
Min nTPM: 153.5
Sample A Female 153.5
Sample B Female 189.5
Sample C Male 177.0
Sample D Male 162.8

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

62.2
Mouse sample Sample description nTPM
Midbrain
nTPM: 62.2
Samples: 4

Max nTPM: 74.6
Min nTPM: 50.5
Sample A 74.6
Sample B 70.0
Sample C 50.5
Sample D 53.6

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