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BETA
  • SUMMARY

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EVOLUTIONARY PONS Show tissue menu
BRAIN74 EYE4 ENDOCRINE TISSUES5 RESPIRATORY SYSTEM6 PROXIMAL DIGESTIVE TRACT5 GASTROINTESTINAL TRACT11 LIVER & GALLBLADDER4 PANCREAS1 KIDNEY & URINARY BLADDER4 MALE REPRODUCTIVE SYSTEM11 BREAST & FEMALE REPRODUCTIVE SYSTEM10 MUSCLE & VASCULAR TISSUE12 CONNECTIVE & SOFT TISSUE15 SKIN4 BONE MARROW & LYMPHOID TISSUES7
Select an organ to show its tissues
AMYGDALA ANGULAR GYRUS ANNECTANT GYRUS ANTERIOR CINGULATE GYRUS BASAL GANGLIA CAUDATE NUCLEUS CAUDATE PUTAMEN CEREBELLUM CEREBRAL CORTEX CHOROID PLEXUS CINGULATE CORTEX CLAUSTRUM CORPUS CALLOSUM CUNEUS DORSAL HIPPOCAMPUS DORSAL ROOT GANGLION DORSAL SPINAL CORD ENTORHINAL CORTEX FRONTAL CORTEX
FUSIFORM GYRUS GENICULATE NUCLEUS GLOBUS PALLIDUS GYRUS RECTUS HABENULA HIPPOCAMPAL FORMATION HYPOTHALAMUS HYPOTHALAMUS, ANTERIOR HYPOTHALAMUS, POSTERIOR INFERIOR FRONTAL GYRUS INFERIOR OCCIPITAL GYRUS INFERIOR TEMPORAL GYRUS INSULAR CORTEX LATERAL THALAMIC NUCLEI MEDULLA OBLONGATA MIDBRAIN MIDDLE FRONTAL GYRUS MIDDLE TEMPORAL GYRUS MOTOR AND PREFRONTAL CORTEX
MOTOR CORTEX OCCIPITAL CORTEX OCCIPITAL GYRUS OLFACTORY BULB ORBITAL GYRUS PERIAQUEDUCTAL GRAY PONS POSTCENTRAL GYRUS POSTERIOR CINGULATE CORTEX POSTERIOR PARAHIPPOCAMPAL GYRUS POSTERIOR THALAMUS PRECENTRAL GYRUS PREFRONTAL CORTEX PREOPTIC AREA PUTAMEN RETROSPLENIAL AND CINGULATE CORTEX RETROSPLENIAL CORTEX SEPTAL AREA SEPTUM
SOMATOSENSORY CORTEX SPINAL CORD SUBICULUM SUBSTANTIA NIGRA SUPERIOR COLLICULI SUPERIOR FRONTAL GYRUS SUPERIOR PARIETAL LOBULE SUPERIOR TEMPORAL GYRUS SUPRAMARGINAL GYRUS TEMPORAL CORTEX THALAMUS VENTRAL FOREBRAIN VENTRAL HIPPOCAMPUS VENTRAL PALLIDUM VENTRAL SPINAL CORD VISUAL CORTEX WHITE MATTER
CORNEA HARDERIAN GLAND LENS RETINA
ADRENAL GLAND PARATHYROID GLAND PINEAL GLAND PITUITARY GLAND THYROID GLAND
BRONCHUS LARYNX LUNG NASOPHARYNX OLFACTORY EPITHELIUM TRACHEA
ESOPHAGUS LIP ORAL MUCOSA SALIVARY GLAND TONGUE
CECUM COLON DUODENUM ILEUM JEJUNUM RECTUM SMALL INTESTINE STOMACH STOMACH (LOWER) STOMACH (MIDDLE) STOMACH (UPPER)
GALLBLADDER LIVER LIVER (LOBE 1) LIVER (LOBE 4)
PANCREAS
KIDNEY KIDNEY (CORTEX) KIDNEY (MEDULLA) URINARY BLADDER
BULBOURETHRAL GLAND DUCTUS DEFERENS EPIDIDYMIS MALE PREPUTIAL GLAND PENIS PROSTATE PROSTATE (ANTERIOR) PROSTATE (VENTRAL) SEMINAL VESICLE TESTIS URETHRAL GLAND
BREAST CERVIX CLITORIS ENDOMETRIUM FALLOPIAN TUBE FEMALE PREPUTIAL GLAND OVARY PLACENTA UTERUS VAGINA
AORTA BLOOD VESSEL DIAPHRAGM HEART ATRIUM HEART MUSCLE HEART VALVE HEART WALL PERIPHERAL VASCULATURE SKELETAL MUSCLE SMOOTH MUSCLE SMOOTH MUSCLE (INTESTINE) SMOOTH MUSCLE (UTERUS)
ABDOMINAL ADIPOSE TISSUE ADIPOSE TISSUE BROWN ADIPOSE TISSUE DURA MATER EAR CANAL EAR CARTILAGE JOINT CARTILAGE MENINGES ORBITAL ADIPOSE TISSUE PERICARDIUM PERITONEUM PLEURA SUBCUTANEOUS ADIPOSE TISSUE SYNOVIAL TISSUE VAGUS NERVE
EYE LID SKIN SKIN (BACK) SKIN (GROIN)
APPENDIX BLOOD, PBMC BONE MARROW LYMPH NODE SPLEEN THYMUS TONSIL
HumanMacaqueMouseRatPig
PRIMARY MOUSE DATA
ANTIBODIES
AND
VALIDATION
Protein evolution
Brain
Evolutionary methods
PONS - Expression summary
Mouse brain, Intensity
Ponsi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

21.937
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

HPA Brain:1738.1 nTPM
FANTOM5:1024.7 Scaled Tags Per Million
Macaque:693.4 nTPM
Mouse:827.3 nTPM
Rat:888.0 nTPM
Pig:1521.4 nTPM
BRAIN - SINGLE CELL RNA EXPRESSION
Explore single cell type data

PONS - Mouse brain profilei

Protein expression in mouse brain using immunofluorescence is reported as fluorescence intensity.

, antibody HPA067442
Pons mean intensity 21.937
intensityi

Protein expression in mouse brain using immunofluorescence is reported as mean fluorescence intensity.

FRONT BACK
Barrington's nucleus -
Koelliker-fuse nucleus -
Motor tregiminal nucleus 1.152
Parabrachial nucleus 3.334
Principle sensory trigeminal nucleus 8.950
Locus coeruleus 0.722
Pontine nucleus 21.937
Vestibular nucleus 11.235
Pontine reticular nucleus, oral 0.656
Lateral lemniscus 17.804
Superior paraolivary nucleus 13.953

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1738.1
Sample id Sample description nTPM
Anterior cochlear nucleus, ventral
nTPM: 799.5
1984 Male, age 76, both hemispheres 1011.7
2301 Female, age 85, both hemispheres 812.0
2188 Female, age 91, both hemispheres 768.3
2090 Male, age 80, both hemispheres 606.0
Dorsal cochlear nucleus
nTPM: 724.0
2058 Male, age 76, both hemispheres 900.9
2802 Male, age 74, right hemisphere 731.4
2370 Male, age 61, both hemispheres 692.4
2187 Female, age 91, both hemispheres 679.9
2378 Male, age 80, both hemispheres 615.7
Dorsal tegmental nucleus
nTPM: 711.8
2083 Male, age 80, both hemispheres 889.1
1936 Male, age 76, left hemisphere 846.9
2326 Male, age 74, both hemispheres 683.1
2358 Male, age 61, both hemispheres 428.0
Dorsolateral tegmental area
nTPM: 687.9
2654 Male, age 80, both hemispheres 882.8
2751 Female, age 85, both hemispheres 881.5
2141 Male, age 76, both hemispheres 793.4
2360 Male, age 74, both hemispheres 658.3
2337 Male, age 61, both hemispheres 223.6
Kolliker-Fuse nucleus
nTPM: 1015.4
2163 Male, age 80, both hemispheres 1328.4
2315 Male, age 76, right hemisphere 909.3
2793 Female, age 91, left hemisphere 808.6
Lateral lemniscal nuclei
nTPM: 1253.6
2169 Male, age 76, both hemispheres 1776.7
2036 Male, age 80, both hemispheres 1633.2
2746 Female, age 85, left hemisphere 1174.9
2453 Male, age 74, right hemisphere 882.8
2320 Female, age 91, left hemisphere 800.2
Lateral parabrachial nucleus
nTPM: 1000.3
2139 Female, age 85, right hemisphere 1524.2
2013 Male, age 80, both hemispheres 991.1
2790 Male, age 61, both hemispheres 775.4
2792 Male, age 76, both hemispheres 710.3
Lateral vestibular nucleus
nTPM: 1051.1
2184 Male, age 76, both hemispheres 1342.6
2311 Male, age 80, both hemispheres 759.5
Locus coeruleus
nTPM: 917.8
2123 Female, age 91, both hemispheres 1073.0
2317 Female, age 72, unknown 1026.2
2014 Male, age 55, unknown 973.6
1980 Male, age 76, both hemispheres 858.7
2720 Male, age 74, both hemispheres 848.4
2788 Male, age 74, unknown 824.8
2162 Male, age 80, both hemispheres 820.1
Medial parabrachial nucleus
nTPM: 872.9
2854 Male, age 80, both hemispheres 1006.1
2156 Male, age 61, both hemispheres 916.9
2786 Male, age 76, both hemispheres 814.2
2463 Female, age 85, right hemisphere 813.9
2170 Female, age 91, both hemispheres 813.4
Medial periolivary nuclei
nTPM: 1199.2
2063 Male, age 76, both hemispheres 1873.6
2171 Female, age 85, both hemispheres 1695.8
2791 Male, age 74, right hemisphere 1079.3
2081 Male, age 80, both hemispheres 694.8
2458 Female, age 91, both hemispheres 652.6
Motor facial nucleus
nTPM: 1195.7
2062 Male, age 76, both hemispheres 2043.7
2795 Female, age 91, both hemispheres 1200.2
2327 Male, age 80, both hemispheres 1125.5
2365 Male, age 74, right hemisphere 1031.0
2697 Female, age 85, both hemispheres 909.2
2126 Male, age 61, both hemispheres 864.6
Motor trigeminal nucleus
nTPM: 867.5
2079 Male, age 80, both hemispheres 1369.1
2309 Male, age 76, both hemispheres 835.7
2560 Male, age 74, both hemispheres 782.7
2335 Male, age 61, both hemispheres 771.4
2321 Female, age 91, both hemispheres 578.5
Nuclei of the trapezoid body
nTPM: 1738.1
2159 Male, age 61, both hemispheres 2970.6
1983 Male, age 76, both hemispheres 1879.6
2735 Female, age 85, both hemispheres 1778.0
2166 Male, age 80, both hemispheres 1125.2
2368 Female, age 91, both hemispheres 937.3
Nucleus raphe magnus
nTPM: 1557.7
2160 Male, age 61, both hemispheres 3320.7
2172 Female, age 85, both hemispheres 1613.2
2455 Male, age 74, both hemispheres 1322.6
2328 Male, age 80, both hemispheres 1229.1
2051 Male, age 76, both hemispheres 1184.4
2459 Female, age 91, both hemispheres 676.1
Paramedian reticular nucleus
nTPM: 1064.1
2050 Female, age 85, both hemispheres 1359.1
2057 Male, age 80, both hemispheres 1125.4
2313 Male, age 61, both hemispheres 1112.9
2052 Male, age 76, both hemispheres 659.0
Pedunculopontine tegmental nucleus
nTPM: 851.4
1921 Female, age 85, both hemispheres 1048.1
2334 Male, age 80, both hemispheres 852.4
2338 Male, age 61, both hemispheres 653.8
Pontine nuclei
nTPM: 1441.7
2727 Male, age 61, right hemisphere 2917.4
2787 Female, age 85, both hemispheres 1796.3
1863 Male, age 55, unknown 1767.5
1968 Male, age 76, left hemisphere 1607.4
2109 Female, age 72, unknown 1160.2
2115 Male, age 80, left hemisphere 836.1
2319 Female, age 91, both hemispheres 763.1
2454 Male, age 74, left hemisphere 685.7
Pontine raphe nucleus
nTPM: 1132.0
2122 Female, age 85, midline 1398.0
2853 Male, age 76, midline 866.0
Posteroventral cochlear nucleus
nTPM: 759.4
2752 Female, age 85, both hemispheres 1095.4
2070 Male, age 76, both hemispheres 830.7
2371 Male, age 61, both hemispheres 761.6
2135 Female, age 91, both hemispheres 601.4
2341 Male, age 80, both hemispheres 507.9
Principal sensory trigeminal nucleus
nTPM: 1566.1
2158 Male, age 61, both hemispheres 2814.1
2008 Male, age 80, left hemisphere 1587.9
2324 Male, age 76, both hemispheres 1206.4
2367 Female, age 91, left hemisphere 656.0
Reticular pontine nucleus, caudal
nTPM: 1006.6
2092 Male, age 76, both hemispheres 1461.2
2332 Male, age 80, right hemisphere 1334.5
2457 Female, age 91, both hemispheres 715.8
2559 Male, age 74, both hemispheres 514.9
Reticular pontine nucleus, oral
nTPM: 883.4
2012 Female, age 85, both hemispheres 1245.3
1939 Male, age 80, both hemispheres 858.9
2167 Male, age 76, both hemispheres 847.0
2366 Female, age 91, both hemispheres 776.4
2361 Male, age 74, both hemispheres 689.4
Reticulotegmental nucleus
nTPM: 935.0
2325 Male, age 76, both hemispheres 1232.7
2333 Male, age 80, both hemispheres 976.5
2322 Female, age 91, both hemispheres 821.0
2452 Male, age 74, both hemispheres 709.9
Spinal trigeminal nucleus, oral
nTPM: 938.5
2737 Female, age 85, both hemispheres 1109.1
2164 Male, age 80, both hemispheres 953.1
1978 Male, age 76, both hemispheres 753.3
Subcoeruleus area
nTPM: 953.0
2089 Male, age 76, left hemisphere 1246.3
1958 Male, age 80, both hemispheres 1169.6
2323 Female, age 91, left hemisphere 838.3
2451 Male, age 74, both hemispheres 759.0
2369 Female, age 85, left hemisphere 751.9
Superior olive
nTPM: 1154.7
1875 Female, age 85, both hemispheres 1522.7
2020 Male, age 76, both hemispheres 1330.5
2329 Male, age 80, right hemisphere 1105.0
2364 Male, age 74, right hemisphere 1086.5
2561 Female, age 91, both hemispheres 728.7
Ventral periolivary nuclei
nTPM: 1379.9
2130 Female, age 85, both hemispheres 1813.8
2165 Male, age 80, both hemispheres 1671.1
2023 Male, age 76, both hemispheres 1248.6
2794 Female, age 91, left hemisphere 786.4
Ventrolateral tegmental area, A5 NE cell group
nTPM: 948.4
1959 Male, age 76, both hemispheres 1366.3
2161 Male, age 80, both hemispheres 1046.3
2449 Male, age 74, both hemispheres 976.9
2840 Female, age 85, both hemispheres 958.0
2456 Female, age 91, both hemispheres 764.2
2359 Male, age 61, both hemispheres 578.7

PONS - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

1024.7
FANTOM5 sample id Sample description Scaled Tags Per Million
Locus coeruleus
Scaled Tags Per Million: 503.9
FF:10182-103D2 60 years, female 649.9
FF:10165-103B3 76 years, female 357.9
Pons
Scaled Tags Per Million: 1024.7
FF:10033-101E6 18-54 years, mixed 1024.7

PONS - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

693.4
Macaque sample Sample description nTPM
Pons
nTPM: 693.3
Samples: 2

Max nTPM: 810.3
Min nTPM: 576.4
Sample A 810.3
Sample B 576.4

PONS - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1521.4
Pig sample Sample description nTPM
Pons
nTPM: 1521.3
Samples: 3

Max nTPM: 1736.2
Min nTPM: 1265.9
Sample A Female 1736.2
Sample B Female 1265.9
Sample C Male 1561.9

PONS - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

827.3
Mouse sample Sample description nTPM
Pons
nTPM: 827.4
Samples: 4

Max nTPM: 875.2
Min nTPM: 729.6
Sample A 729.6
Sample B 875.2
Sample C 841.1
Sample D 863.5

PONS - Rat RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

888.0
Rat sample Sample description nTPM
Pons
nTPM: 888.0
Samples: 4

Max nTPM: 925.1
Min nTPM: 854.0
Sample A 902.2
Sample A 925.1
Sample A 854.0
Sample A 870.5

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