BETA
CEREBRAL CORTEX - Expression summary
Protein expression
Cerebral cortexi
h
m
l
n
Endothelial cells: Not detected
Glial cells: High
Neuronal cells: High
Neuropil: Not detected
RNA expressioni
Consensus:1173.3 nTPM
HPA:335.7 nTPM
HPA Brain:576.2 nTPM
HPA PFC Brain:1234.9 nTPM
GTEx:1173.3 nTPM
FANTOM5:388.6 Scaled Tags Per Million
Macaque:146.2 nTPM
Mouse:127.7 nTPM
Rat:3.4 nTPM
Pig:320.3 nTPM
CEREBRAL CORTEX - SINGLE NUCLEI RNA EXPRESSIONi

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NEURONSi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 80
c-1 Excitatory (VGLUT1) CUX2+
c-2 Inhibitory (GAD1/2) LHX6+ T...
c-3 Inhibitory (GAD1/2) CXCL14+...
c-4 Inhibitory (GAD1/2) LHX6+ T...
c-5 Inhibitory (GAD1/2) CXCL14+
c-6 Excitatory (VGLUT1) FOXP2+
c-7 Excitatory (VGLUT1) CUX2+
c-8 Excitatory (VGLUT1)
c-9 Inhibitory (GAD1/2) LHX6+ T...
c-10 Inhibitory (GAD1/2) CXCL14+...
c-11 Inhibitory (GAD1/2) CXCL14+...
c-12 Excitatory (VGLUT1) FOXP2+
c-13 Excitatory (VGLUT1) FOXP2+
c-14 Excitatory (VGLUT1) CUX2+
c-15 Excitatory (VGLUT1) FOXP2+
c-16 Inhibitory (GAD1/2) CXCL14+...
c-17 Excitatory (VGLUT1/2)
c-18 Excitatory (VGLUT1) FOXP2+
c-19 Excitatory (VGLUT1/2) CUX2+
c-20 Inhibitory (GAD1/2) LAMP5+ ...
c-21 Excitatory (VGLUT1) FOXP2+
c-22 Inhibitory (GAD1/2) CXCL14+
c-23 Excitatory (VGLUT1) FOXP2+
c-24 Excitatory (VGLUT1) SOX5+
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - CEREBRAL CORTEX, NON-NEURONALi
Cell type color
Cluster color
Colored according to cell type group
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 450
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Oligodendrocyte progenitor ...
c-4 Oligodendrocytes
c-5 Astrocytes
c-6 Astrocytes
c-7 Microglia
c-8 Oligodendrocyte progenitor ...
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Astrocytes
c-12 Astrocytes
c-13 Astrocytes
c-14 Microglia
c-15 Vascular endothelial cells
c-16 Fibroblasts
c-17 Oligodendrocytes (CNTN1+)
c-18 Macrophages
c-19 Immature oligodendrocytes
c-20 Oligodendrocyte progenitor ...
c-21 Pericytes
c-22 Lymphocytes
c-23 Fibroblasts
c-24 Vascular smooth muscle cell
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

CEREBRAL CORTEX - Antibody stainingi
Antibody HPA006047
Endothelial cells Not detected
Glial cells High
Neuronal cells High
Neuropil Not detected


CEREBRAL CORTEX - PROTEINTALKS DB MS
Median intensity 41706
Sample Intensity
Cerebral cortex_01
 41048
Cerebral cortex_02
 48906
Cerebral cortex_03
 120967
Cerebral cortex_04
 43634
Cerebral cortex_05
 32607
Cerebral cortex_06
 55149
Cerebral cortex_07
 57969
Cerebral cortex_08
 46768
Cerebral cortex_09
 64135
Cerebral cortex_10
 58829
Cerebral cortex_11
 40238
Cerebral cortex_12
 53995
Cerebral cortex_13
 50485
Cerebral cortex_14
 38042
Cerebral cortex_15
 71121
Cerebral cortex_16
 38165
Cerebral cortex_17
 33090
Cerebral cortex_18
 32749
Cerebral cortex_19
 55936
Cerebral cortex_20
 57816
Cerebral cortex_21
 35261
Cerebral cortex_22
 42105
Cerebral cortex_23
 35790
Cerebral cortex_24
 32333
Cerebral cortex_25
 34075
Cerebral cortex_26
 35686
Cerebral cortex_27
 30163
Cerebral cortex_28
 37338
Cerebral cortex_29
 34010
Cerebral cortex_30
 41307
Cerebral cortex_31
 35183
Cerebral cortex_32
 46754
Cerebral cortex_33
 100601
Cerebral cortex_34
 33064
Cerebral cortex_35
 62662
Cerebral cortex_36
 36270
Cerebral cortex_37
 44171
Cerebral cortex_38
 47504

CEREBRAL CORTEX - MANN MS
Median intensity 6296248
Replicate Intensity
Cerebral cortex_01
 5755786
Cerebral cortex_02
 6347762
Cerebral cortex_03
 6296248

CEREBRAL CORTEX - HPA RNA-seqi
Average nTPMi 335.7
N/A
Male, age 5
Cerebral cortex sample 48
nTPM: 277.3
overview
Female, age 40
Cerebral cortex sample 105
nTPM: 377.7
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65
overview
Male, age 70
Cerebral cortex sample 106
nTPM: 352.1
Cell types%
Neuronal cells:
35

Glial cells and endothelial cells:
65

CEREBRAL CORTEX - HPA Brain Stereo-seq

CEREBRAL CORTEX - HPA Brain RNA-seq
Max subtype nTPMi 576.2
Sample id Sample description nTPM
Angular gyrus
nTPM: 367.5
1790 Male, age 76, right hemisphere 458.8
2103 Male, age 75, left hemisphere 440.2
1866 Male, age 76, both hemispheres 383.2
2722 Male, age 61, left hemisphere 369.4
2260 Female, age 72, left hemisphere 352.3
2602 Female, age 94, right hemisphere 339.5
2265 Female, age 91, left hemisphere 324.7
2221 Female, age 67, right hemisphere 271.7
Angular gyrus (white matter)
nTPM: 495.3
1920 Male, age 76, both hemispheres 495.3
Anterior cingulate cortex, supragenual-dorsal
nTPM: 349.9
2547 Male, age 74, left hemisphere 398.0
2478 Female, age 67, right hemisphere 396.0
1896 Female, age 85, right hemisphere 358.4
2342 Female, age 94, right hemisphere 301.4
2472 Male, age 75, left hemisphere 295.5
Anterior cingulate cortex, supragenual-ventral
nTPM: 377.2
2479 Female, age 67, right hemisphere 435.9
1761 Male, age 74, left hemisphere 420.5
1950 Female, age 85, right hemisphere 367.5
2538 Male, age 75, left hemisphere 339.1
1755 Female, age 94, right hemisphere 322.7
Anterior insular cortex, dorsal
nTPM: 372.9
2235 Female, age 91, right hemisphere 419.2
2670 Male, age 75, left hemisphere 390.8
2001 Male, age 76, right hemisphere 366.3
2506 Female, age 94, right hemisphere 315.3
Anterior insular cortex, ventral
nTPM: 349.3
2596 Male, age 75, left hemisphere 411.5
1925 Female, age 91, left hemisphere 396.5
1852 Male, age 76, left hemisphere 370.8
2262 Female, age 67, right hemisphere 349.4
2507 Female, age 94, left hemisphere 299.3
2757 Male, age 61, right hemisphere 268.4
Area parastriata, inferior
nTPM: 425.5
2509 Female, age 94, left hemisphere 604.8
2234 Male, age 75, left hemisphere 575.1
1789 Male, age 76, right hemisphere 459.0
1758 Female, age 72, right hemisphere 374.7
1760 Female, age 67, left hemisphere 341.1
2421 Female, age 91, left hemisphere 326.3
2268 Male, age 61, right hemisphere 297.8
Area parastriata, parietal
nTPM: 390.5
2420 Male, age 75, left hemisphere 403.9
2236 Female, age 91, left hemisphere 403.1
1785 Male, age 76, right hemisphere 400.4
2233 Male, age 61, right hemisphere 393.6
2680 Female, age 94, right hemisphere 351.3
Area parastriata, superior
nTPM: 505.5
2435 Male, age 61, left hemisphere 706.2
2604 Female, age 94, right hemisphere 645.6
2881 Male, age 76, left hemisphere 467.0
2684 Female, age 67, left hemisphere 445.8
1773 Female, age 91, left hemisphere 445.3
2419 Male, age 75, right hemisphere 323.1
Area parastriata, temporal
nTPM: 355.9
1804 Male, age 76, right hemisphere 426.8
2471 Male, age 75, left hemisphere 375.4
2681 Female, age 94, right hemisphere 363.0
2267 Male, age 61, right hemisphere 318.4
2424 Female, age 67, left hemisphere 296.0
Area striata
nTPM: 361.8
1884 Male, age 76, left hemisphere 534.6
1753 Female, age 72, right hemisphere 416.2
2002 Female, age 91, right hemisphere 385.0
2679 Female, age 94, right hemisphere 337.4
2417 Male, age 61, right hemisphere 251.6
2427 Female, age 91, left hemisphere 246.1
Area striata (white matter)
nTPM: 519.7
2258 Female, age 91, left hemisphere 519.7
Claustrum
nTPM: 405.5
2196 Female, age 79, unknown 579.4
1956 Male, age 74, unknown 443.0
2292 Female, age 85, both hemispheres 440.3
2491 Male, age 75, both hemispheres 437.5
2198 Male, age 80, both hemispheres 423.2
2392 Female, age 94, both hemispheres 389.5
2284 Female, age 91, both hemispheres 340.0
2645 Female, age 72, unknown 311.3
2568 Male, age 61, both hemispheres 285.3
Corpus callosum, genu (white matter)
nTPM: 523.3
1934 Male, age 61, right hemisphere 648.9
1887 Male, age 76, left hemisphere 599.0
1885 Female, age 94, left hemisphere 519.3
1849 Female, age 91, right hemisphere 478.1
1886 Female, age 67, right hemisphere 454.8
2771 Male, age 75, left hemisphere 439.9
Corpus callosum, splenium (white matter)
nTPM: 522.0
1946 Male, age 76, left hemisphere 585.8
2238 Female, age 94, right hemisphere 503.8
2104 Male, age 75, left hemisphere 501.9
2847 Female, age 67, right hemisphere 496.4
Frontal eye field
nTPM: 342.2
2147 Male, age 61, left hemisphere 434.2
2761 Female, age 94, left hemisphere 324.1
2441 Male, age 75, left hemisphere 317.2
2543 Male, age 74, left hemisphere 293.4
Frontal operculum
nTPM: 363.6
2030 Male, age 61, right hemisphere 433.3
2781 Female, age 85, right hemisphere 335.2
2348 Male, age 75, left hemisphere 322.4
Fusiform gyrus
nTPM: 455.6
2431 Male, age 75, right hemisphere 662.5
2074 Female, age 91, left hemisphere 533.4
1807 Male, age 76, left hemisphere 507.2
2784 Female, age 85, left hemisphere 411.1
2433 Female, age 72, left hemisphere 377.7
2617 Female, age 94, left hemisphere 351.7
2112 Male, age 80, both hemispheres 345.3
Inferior frontal gyrus, opercular
nTPM: 380.5
2874 Female, age 85, right hemisphere 483.6
2873 Female, age 85, left hemisphere 463.4
2866 Male, age 61, right hemisphere 462.2
2875 Female, age 67, left hemisphere 366.1
2865 Male, age 61, left hemisphere 365.0
2869 Male, age 74, left hemisphere 354.3
2868 Male, age 75, right hemisphere 346.0
2871 Female, age 94, left hemisphere 342.3
2872 Female, age 94, right hemisphere 312.2
2867 Male, age 75, left hemisphere 310.2
Inferior parietal lobule
nTPM: 340.4
2606 Female, age 67, right hemisphere 466.3
2876 Male, age 76, right hemisphere 343.5
2599 Female, age 94, left hemisphere 304.5
2418 Male, age 75, left hemisphere 247.2
Inferior temporal gyrus
nTPM: 394.4
1808 Male, age 76, left hemisphere 443.3
1970 Female, age 85, right hemisphere 435.3
2430 Male, age 75, right hemisphere 425.9
1880 Male, age 80, right hemisphere 375.9
1965 Female, age 91, left hemisphere 348.9
2689 Female, age 94, right hemisphere 336.9
Intraparietal deep sulcus
nTPM: 374.4
2607 Female, age 67, right hemisphere 408.7
2600 Female, age 94, right hemisphere 407.1
2230 Male, age 61, right hemisphere 397.2
2102 Female, age 91, left hemisphere 376.3
2798 Male, age 76, left hemisphere 332.2
2669 Male, age 75, left hemisphere 324.6
Lingual gyrus
nTPM: 394.3
1893 Male, age 76, left hemisphere 413.9
2618 Female, age 94, left hemisphere 413.1
2073 Female, age 85, left hemisphere 408.2
2688 Male, age 75, right hemisphere 406.0
2838 Male, age 80, right hemisphere 330.1
Middle cingulate cortex
nTPM: 362.4
2640 Female, age 94, right hemisphere 485.6
2633 Male, age 74, left hemisphere 373.4
2028 Female, age 85, left hemisphere 366.9
2539 Male, age 75, left hemisphere 315.4
2357 Female, age 67, right hemisphere 270.9
Middle temporal gyrus
nTPM: 358.1
1819 Male, age 80, right hemisphere 423.0
1799 Male, age 76, left hemisphere 397.1
2616 Female, age 94, left hemisphere 375.8
2611 Male, age 75, right hemisphere 311.7
2034 Female, age 91, right hemisphere 282.9
Occipital cortex
nTPM: 311.0
1842 Male, age 76, right hemisphere 340.3
2677 Female, age 67, right hemisphere 328.8
2470 Male, age 75, right hemisphere 315.2
2608 Female, age 67, both hemispheres 287.0
2426 Male, age 75, midline 283.6
Occipital cortex (white matter)
nTPM: 466.1
2259 Male, age 75, midline 578.7
2257 Female, age 67, both hemispheres 353.5
Olfactory area
nTPM: 365.2
1805 Female, age 85, right hemisphere 534.0
2542 Male, age 74, left hemisphere 393.9
2222 Female, age 67, right hemisphere 347.6
2756 Female, age 67, right hemisphere 343.5
2440 Male, age 75, left hemisphere 341.3
2352 Female, age 94, right hemisphere 230.9
Olfactory tubercle
nTPM: 374.6
1846 Male, age 80, right hemisphere 406.6
1998 Female, age 91, both hemispheres 393.2
2856 Male, age 75, right hemisphere 352.3
2487 Female, age 94, left hemisphere 346.2
Orbitofrontal gyrus, anterior
nTPM: 426.8
2863 Female, age 85, right hemisphere 568.8
2864 Female, age 67, left hemisphere 415.5
2862 Female, age 85, left hemisphere 295.9
Paracentral lobule, anterior
nTPM: 365.3
1776 Female, age 85, right hemisphere 466.6
1754 Male, age 75, left hemisphere 389.6
2340 Female, age 67, right hemisphere 379.5
1926 Male, age 61, left hemisphere 334.5
2638 Female, age 94, right hemisphere 311.8
2474 Male, age 74, left hemisphere 309.8
Paracentral lobule, posterior
nTPM: 359.2
1775 Female, age 85, right hemisphere 449.9
2551 Female, age 94, right hemisphere 388.9
2446 Male, age 75, left hemisphere 339.1
1764 Male, age 74, right hemisphere 335.2
2345 Male, age 61, left hemisphere 283.0
Parahippocampal cortex (white matter)
nTPM: 441.1
2157 Female, age 91, both hemispheres 441.1
Parietal operculum
nTPM: 305.4
1763 Male, age 74, left hemisphere 339.2
2719 Male, age 75, left hemisphere 335.6
2552 Female, age 94, right hemisphere 278.3
2356 Female, age 67, right hemisphere 268.4
Parieto-insular cortex
nTPM: 343.2
1976 Female, age 91, right hemisphere 396.5
2831 Male, age 76, right hemisphere 371.0
2508 Female, age 94, right hemisphere 327.3
2671 Male, age 75, left hemisphere 315.9
2232 Male, age 61, right hemisphere 305.2
Parieto-occipital transitional area
nTPM: 376.6
2683 Female, age 67, left hemisphere 478.5
1784 Male, age 76, right hemisphere 398.7
2468 Male, age 75, left hemisphere 350.3
2674 Female, age 94, right hemisphere 336.3
2270 Male, age 61, right hemisphere 319.4
Parieto-temporal junction (white matter)
nTPM: 492.1
2774 Male, age 61, right hemisphere 557.9
1935 Female, age 94, right hemisphere 522.3
2121 Male, age 76, left hemisphere 519.1
2469 Male, age 75, right hemisphere 494.9
1999 Female, age 67, right hemisphere 447.4
2770 Female, age 91, right hemisphere 410.7
Piriform cortex
nTPM: 403.3
2347 Male, age 75, right hemisphere 451.1
2153 Female, age 85, left hemisphere 355.5
Postcentral gyrus
nTPM: 311.6
2533 Male, age 75, right hemisphere 311.6
Postcentral gyrus, dorsal
nTPM: 378.1
2350 Male, age 75, left hemisphere 434.7
1836 Female, age 85, right hemisphere 428.5
2477 Female, age 94, right hemisphere 406.1
2339 Female, age 67, right hemisphere 358.6
2151 Male, age 61, left hemisphere 339.4
2544 Male, age 74, left hemisphere 301.3
Postcentral gyrus, middle
nTPM: 297.5
1897 Female, age 85, right hemisphere 357.7
2248 Male, age 61, left hemisphere 306.0
2545 Male, age 74, left hemisphere 305.1
2146 Female, age 67, right hemisphere 280.9
2444 Male, age 75, left hemisphere 237.9
Postcentral gyrus, ventral
nTPM: 366.0
2836 Female, age 94, right hemisphere 390.9
2024 Female, age 85, right hemisphere 366.6
2445 Male, age 75, left hemisphere 340.4
Posterior cingulate cortex
nTPM: 353.4
2473 Male, age 75, left hemisphere 394.1
1759 Male, age 74, right hemisphere 333.8
2553 Female, age 94, right hemisphere 332.4
Posterior cingulate cortex, dorsal
nTPM: 406.0
2343 Male, age 61, left hemisphere 516.6
2634 Male, age 74, left hemisphere 440.6
2556 Female, age 67, right hemisphere 432.9
2076 Female, age 85, right hemisphere 373.4
2641 Female, age 94, right hemisphere 356.9
2540 Male, age 75, right hemisphere 315.2
Posterior cingulate cortex, ventral
nTPM: 331.8
1994 Female, age 85, right hemisphere 383.6
1762 Female, age 94, right hemisphere 352.6
2541 Male, age 75, right hemisphere 346.3
2448 Female, age 67, right hemisphere 332.7
2635 Male, age 74, left hemisphere 329.0
2346 Male, age 61, left hemisphere 246.3
Posterior insular cortex
nTPM: 332.1
2832 Female, age 91, right hemisphere 414.8
2511 Female, age 67, right hemisphere 399.7
1823 Male, age 76, right hemisphere 331.4
2603 Female, age 94, left hemisphere 295.1
2597 Male, age 75, left hemisphere 287.9
2231 Male, age 61, left hemisphere 263.9
Precentral gyrus
nTPM: 246.0
2557 Male, age 75, right hemisphere 246.0
Precentral gyrus, dorsal
nTPM: 349.0
1756 Male, age 74, left hemisphere 419.3
2442 Male, age 75, left hemisphere 362.4
2476 Female, age 94, right hemisphere 348.8
2354 Female, age 67, right hemisphere 265.4
Precentral gyrus, middle
nTPM: 321.5
2475 Male, age 74, right hemisphere 381.4
1969 Female, age 67, right hemisphere 319.6
2443 Male, age 75, left hemisphere 307.1
2549 Female, age 94, right hemisphere 301.5
1909 Male, age 61, left hemisphere 297.9
Precentral gyrus, ventral
nTPM: 331.8
2550 Female, age 94, right hemisphere 355.4
2678 Male, age 74, left hemisphere 337.0
2662 Female, age 67, right hemisphere 320.4
2630 Male, age 75, left hemisphere 314.3
Precuneus
nTPM: 389.9
2467 Male, age 75, right hemisphere 450.3
2510 Female, age 67, right hemisphere 410.5
1782 Male, age 76, right hemisphere 404.2
2673 Female, age 94, right hemisphere 379.9
1780 Female, age 91, right hemisphere 372.7
2594 Male, age 61, left hemisphere 321.8
Premotor cortex, dorsal
nTPM: 341.7
2554 Female, age 67, right hemisphere 404.0
1878 Female, age 85, right hemisphere 375.8
2536 Male, age 75, left hemisphere 328.0
2631 Male, age 74, left hemisphere 317.9
2027 Male, age 61, left hemisphere 282.7
Premotor cortex, ventral
nTPM: 327.0
1779 Male, age 61, left hemisphere 364.5
1777 Female, age 67, left hemisphere 344.7
1757 Male, age 74, left hemisphere 342.6
1881 Female, age 85, right hemisphere 331.1
2349 Male, age 75, left hemisphere 318.9
2637 Female, age 94, right hemisphere 260.3
Retrosplenial cortex
nTPM: 404.4
1914 Male, age 76, right hemisphere 434.7
2675 Female, age 94, left hemisphere 392.1
1951 Male, age 61, right hemisphere 386.3
Somatomor cortex, precentral gyrus (white matter)
nTPM: 450.5
2439 Male, age 75, right hemisphere 450.5
Somatosensory cortex, postcentral gyrus, ventral (white matter)
nTPM: 389.9
2623 Male, age 75, right hemisphere 389.9
Subcentral gyrus, S2
nTPM: 345.9
2555 Female, age 67, right hemisphere 414.2
2762 Male, age 74, left hemisphere 373.8
2072 Male, age 61, left hemisphere 360.5
1964 Female, age 85, right hemisphere 345.0
2351 Male, age 75, left hemisphere 297.8
2839 Female, age 94, right hemisphere 284.1
Superior parietal lobule
nTPM: 360.2
1800 Male, age 76, right hemisphere 438.7
2605 Female, age 67, right hemisphere 389.8
1992 Female, age 91, right hemisphere 349.0
2229 Male, age 61, right hemisphere 314.7
2672 Female, age 94, right hemisphere 308.7
Superior temporal gyrus
nTPM: 334.7
1844 Female, age 91, left hemisphere 407.4
2615 Female, age 94, left hemisphere 338.9
1843 Male, age 76, left hemisphere 332.4
2025 Male, age 80, right hemisphere 320.6
2687 Male, age 75, right hemisphere 274.0
Supplementary motor cortex
nTPM: 295.8
1993 Male, age 61, left hemisphere 326.1
2632 Male, age 74, left hemisphere 318.4
2537 Male, age 75, left hemisphere 269.8
2548 Female, age 94, right hemisphere 269.1
Supramarginal gyrus
nTPM: 355.4
1798 Male, age 76, right hemisphere 380.9
1991 Female, age 91, right hemisphere 376.5
2601 Female, age 94, left hemisphere 357.1
2513 Female, age 72, left hemisphere 351.3
2415 Male, age 61, left hemisphere 311.1
Temporal pole
nTPM: 460.0
2518 Male, age 75, right hemisphere 542.2
1853 Female, age 85, right hemisphere 509.4
1832 Female, age 91, left hemisphere 444.4
2612 Female, age 94, left hemisphere 403.3
1826 Male, age 76, right hemisphere 400.6
Temporal white matter
nTPM: 576.2
2523 Female, age 94, left hemisphere 798.8
1801 Male, age 76, left hemisphere 655.3
2736 Female, age 91, right hemisphere 556.9
2254 Male, age 75, right hemisphere 472.5
2524 Female, age 85, left hemisphere 397.7
Temporo-insular cortex, parainsular gyrus
nTPM: 316.4
1802 Male, age 76, left hemisphere 395.5
2598 Male, age 75, left hemisphere 366.5
2264 Female, age 91, right hemisphere 353.5
2512 Female, age 67, right hemisphere 282.9
2416 Male, age 61, right hemisphere 262.8
2676 Female, age 94, right hemisphere 237.4
Temporo-occipital transitional zone
nTPM: 465.6
1900 Male, age 76, left hemisphere 523.7
1793 Male, age 80, right hemisphere 454.1
2251 Female, age 85, right hemisphere 418.8
Transversal temporal gyrus, anterior
nTPM: 338.8
1888 Female, age 91, left hemisphere 371.0
2522 Female, age 94, left hemisphere 354.2
1910 Male, age 80, right hemisphere 343.0
1809 Male, age 76, right hemisphere 342.7
2610 Male, age 75, right hemisphere 283.1
Transversal temporal gyrus, posterior
nTPM: 342.2
1967 Female, age 91, right hemisphere 397.0
2833 Male, age 80, right hemisphere 346.0
1922 Male, age 76, left hemisphere 341.3
2614 Female, age 94, left hemisphere 333.4
2520 Male, age 75, right hemisphere 293.3

CEREBRAL CORTEX - HPA PFC Brain RNA-seq
Max subtype nTPMi 1234.9
Sample id Sample description nTPM
Anterior cingulate gyrus, pregenual-dorsal
nTPM: 1072.7
1514 Male, age 74, right hemisphere 1619.1
1517 Female, age 67, left hemisphere 1192.1
1518 Female, age 67, right hemisphere 1163.1
1512 Male, age 75, left hemisphere 1149.9
1513 Male, age 74, left hemisphere 1076.3
1515 Female, age 94, right hemisphere 1030.5
1510 Male, age 61, left hemisphere 847.5
1516 Female, age 85, left hemisphere 819.3
1511 Male, age 61, right hemisphere 756.8
Anterior cingulate gyrus, pregenual-ventral
nTPM: 1234.9
1521 Male, age 74, left hemisphere 1687.6
1522 Male, age 74, right hemisphere 1502.5
1523 Female, age 67, left hemisphere 1143.5
1520 Male, age 75, right hemisphere 948.9
1519 Male, age 61, left hemisphere 892.1
Anterior cingulate gyrus, subgenual
nTPM: 1070.3
1527 Male, age 74, left hemisphere 1728.2
1526 Male, age 75, right hemisphere 1213.7
1528 Male, age 74, right hemisphere 1107.9
1525 Male, age 75, left hemisphere 1016.9
1530 Female, age 67, right hemisphere 962.9
1524 Male, age 61, left hemisphere 751.8
1529 Female, age 85, left hemisphere 711.0
Dorsolateral prefrontal cortex
nTPM: 685.1
1450 Female, age 67, right hemisphere 1124.1
1448 Female, age 94, right hemisphere 714.8
1444 Male, age 75, left hemisphere 656.8
1446 Male, age 74, right hemisphere 622.6
1447 Female, age 94, left hemisphere 614.7
1445 Male, age 75, right hemisphere 580.0
1449 Female, age 85, right hemisphere 482.6
Dorsomedial prefrontal cortex
nTPM: 873.1
1442 Male, age 75, right hemisphere 1395.7
1443 Female, age 67, right hemisphere 945.9
1439 Male, age 61, left hemisphere 826.6
1441 Male, age 75, left hemisphere 744.9
1440 Male, age 61, right hemisphere 452.6
Frontomarginal cortex
nTPM: 730.6
1471 Female, age 85, left hemisphere 1357.1
1470 Female, age 94, right hemisphere 923.7
1469 Female, age 94, left hemisphere 812.7
1472 Female, age 67, left hemisphere 800.9
1468 Male, age 74, left hemisphere 745.8
1466 Male, age 61, right hemisphere 530.2
1473 Female, age 67, right hemisphere 526.5
1467 Male, age 75, right hemisphere 485.0
1465 Male, age 61, left hemisphere 393.1
Frontopolar cortex
nTPM: 630.0
1461 Male, age 75, right hemisphere 1102.7
1463 Female, age 67, left hemisphere 812.0
1462 Female, age 94, left hemisphere 698.5
1460 Male, age 75, left hemisphere 471.8
1458 Male, age 61, left hemisphere 450.7
1459 Male, age 61, right hemisphere 444.9
1464 Female, age 67, right hemisphere 429.6
Gyrus rectus
nTPM: 698.1
1478 Female, age 94, left hemisphere 1759.5
1477 Male, age 75, right hemisphere 873.9
1480 Female, age 85, left hemisphere 790.6
1479 Female, age 94, right hemisphere 586.2
1481 Female, age 67, left hemisphere 525.9
1476 Male, age 75, left hemisphere 447.6
1474 Male, age 61, left hemisphere 312.6
1475 Male, age 61, right hemisphere 288.1
Inferior frontal gyrus, orbital
nTPM: 1147.8
1506 Female, age 94, left hemisphere 1561.7
1509 Female, age 67, right hemisphere 1469.4
1507 Female, age 85, left hemisphere 1387.4
1504 Male, age 74, left hemisphere 1362.1
1503 Male, age 75, right hemisphere 1119.3
1505 Male, age 74, right hemisphere 1104.1
1501 Male, age 61, right hemisphere 1076.8
1502 Male, age 75, left hemisphere 1014.7
1500 Male, age 61, left hemisphere 720.9
1508 Female, age 85, right hemisphere 661.8
Inferior frontal gyrus, triangular
nTPM: 1023.8
1545 Male, age 74, right hemisphere 1719.1
1544 Male, age 75, right hemisphere 1353.1
1546 Female, age 94, right hemisphere 1272.5
1549 Female, age 67, left hemisphere 1046.7
1543 Male, age 61, right hemisphere 801.0
1542 Male, age 61, left hemisphere 740.2
1547 Female, age 85, left hemisphere 694.7
1548 Female, age 85, right hemisphere 563.5
Orbitofrontal gyrus, lateral
nTPM: 983.3
1497 Female, age 85, left hemisphere 1563.1
1499 Female, age 67, right hemisphere 1108.2
1495 Female, age 94, left hemisphere 1020.8
1496 Female, age 94, right hemisphere 990.3
1494 Male, age 75, left hemisphere 836.6
1493 Male, age 61, right hemisphere 727.8
1498 Female, age 85, right hemisphere 636.5
Orbitofrontal gyrus, medial
nTPM: 628.0
1485 Male, age 74, left hemisphere 978.1
1492 Female, age 67, right hemisphere 756.4
1491 Female, age 67, left hemisphere 729.1
1482 Male, age 61, left hemisphere 635.9
1483 Male, age 75, left hemisphere 635.0
1488 Female, age 94, right hemisphere 617.6
1487 Female, age 94, left hemisphere 617.0
1489 Female, age 85, left hemisphere 598.1
1484 Male, age 75, right hemisphere 538.8
1490 Female, age 85, right hemisphere 470.0
1486 Male, age 74, right hemisphere 332.6
Orbitofrontal gyrus, posterior
nTPM: 1146.5
1540 Female, age 67, left hemisphere 2036.5
1541 Female, age 67, right hemisphere 1582.7
1535 Male, age 74, left hemisphere 1539.6
1537 Female, age 94, right hemisphere 1269.9
1536 Female, age 94, left hemisphere 1257.4
1534 Male, age 75, right hemisphere 1180.5
1533 Male, age 75, left hemisphere 1015.2
1538 Female, age 85, left hemisphere 781.0
1539 Female, age 85, right hemisphere 774.5
1531 Male, age 61, left hemisphere 621.9
1532 Male, age 61, right hemisphere 552.6
Subcallosal gyrus
nTPM: 782.1
1550 Male, age 61, left hemisphere 1490.8
1560 Female, age 67, left hemisphere 1068.8
1552 Male, age 75, left hemisphere 919.7
1557 Female, age 94, right hemisphere 818.8
1554 Male, age 74, left hemisphere 731.2
1556 Female, age 94, left hemisphere 727.1
1553 Male, age 75, right hemisphere 720.2
1555 Male, age 74, right hemisphere 709.2
1551 Male, age 61, right hemisphere 619.5
1558 Female, age 85, left hemisphere 550.2
1561 Female, age 67, right hemisphere 546.9
1559 Female, age 85, right hemisphere 482.7
Superior frontal gyrus
nTPM: 733.2
1566 Male, age 74, right hemisphere 1125.5
1571 Female, age 67, right hemisphere 1082.0
1565 Male, age 75, right hemisphere 989.6
1564 Male, age 75, left hemisphere 893.7
1567 Female, age 94, left hemisphere 721.3
1562 Male, age 61, left hemisphere 667.9
1563 Male, age 61, right hemisphere 535.4
1568 Female, age 94, right hemisphere 515.6
1570 Female, age 85, right hemisphere 440.6
1569 Female, age 85, left hemisphere 360.2
Temporal cortex
nTPM: 750.3
1595 Female, age 94, right hemisphere 987.8
1593 Male, age 74, right hemisphere 933.8
1592 Male, age 74, left hemisphere 856.8
1591 Male, age 75, right hemisphere 850.6
1594 Female, age 94, left hemisphere 760.2
1596 Female, age 85, right hemisphere 480.4
1590 Male, age 61, right hemisphere 382.4
Ventrolateral prefrontal cortex
nTPM: 754.3
1456 Female, age 67, left hemisphere 908.8
1457 Female, age 67, right hemisphere 814.8
1454 Female, age 94, left hemisphere 784.6
1453 Male, age 74, right hemisphere 739.5
1451 Male, age 75, right hemisphere 722.9
1452 Male, age 74, left hemisphere 719.1
1455 Female, age 85, right hemisphere 590.1
Ventromedial prefrontal cortex
nTPM: 728.8
1435 Female, age 94, right hemisphere 993.6
1432 Male, age 61, left hemisphere 930.6
1438 Female, age 67, left hemisphere 754.6
1434 Male, age 75, right hemisphere 685.5
1433 Male, age 61, right hemisphere 653.9
1436 Female, age 85, left hemisphere 617.3
1437 Female, age 85, right hemisphere 466.0

CEREBRAL CORTEX - GTEx RNA-seqi
Max subtype nTPMi 1173.3
GTEx sample id Sample description nTPM
Brain - Anterior cingulate cortex (BA24)
Average nTPM: 1173.3
Samples: 233

Max nTPM: 3605.9
Min nTPM: 488.7
Std nTPM: 480.8
Median nTPM: 1089.8
GTEX-14JG1-0011-R3a-SM-62LEC 40-49 years, male 3605.9
GTEX-1R46S-0011-R3a-SM-F2TBG 60-69 years, female 3308.4
GTEX-14E6C-0011-R3a-SM-G8W87 40-49 years, male 3167.9
GTEX-139T8-0011-R3b-SM-5HL4R 60-69 years, male 2977.4
GTEX-14E7W-0011-R3b-SM-5YYB5 70-79 years, male 2441.9
GTEX-16XZZ-0011-R3a-SM-7IGLH 60-69 years, male 2441.4
GTEX-1MJK2-0011-R3a-SM-F2TBD 50-59 years, male 2441.2
GTEX-1EH9U-0011-R3b-SM-CL534 60-69 years, male 2308.1
GTEX-1H2FU-0011-R3b-SM-CKZP4 60-69 years, female 2235.3
GTEX-ZAJG-0011-R3a-SM-F21J6 50-59 years, female 2221.9
GTEX-1JMPZ-0011-R3a-SM-EYYWX 30-39 years, male 2009.7
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Brain - Cortex
Average nTPM: 830.3
Samples: 270

Max nTPM: 1751.6
Min nTPM: 428.3
Std nTPM: 269.8
Median nTPM: 751.5
GTEX-15UF6-3026-SM-7KUKL 70-79 years, female 1751.6
GTEX-1N2DW-2826-SM-E9TK5 50-59 years, male 1743.6
GTEX-1LKK1-3126-SM-EWRNY 50-59 years, female 1564.6
GTEX-1LC47-2926-SM-CXZKC 60-69 years, male 1562.4
GTEX-1MA7X-2526-SM-GPI9W 60-69 years, male 1546.0
GTEX-1RLM8-3126-SM-G8LLN 50-59 years, male 1534.5
GTEX-1NV5F-3226-SM-EXUSL 60-69 years, female 1528.2
GTEX-1C6VQ-3026-SM-7IGPU 50-59 years, male 1517.0
GTEX-11NV4-2126-SM-5N9DS 60-69 years, male 1499.3
GTEX-X4XY-3026-SM-EWRM9 60-69 years, male 1470.9
GTEX-ZE7O-3126-SM-5HL5X 50-59 years, female 1438.2
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Brain - Frontal Cortex (BA9)
Average nTPM: 943.3
Samples: 269

Max nTPM: 3244.5
Min nTPM: 338.7
Std nTPM: 453.9
Median nTPM: 822.8
GTEX-1IL2V-0011-R10a-SM-CL55A 70-79 years, male 3244.5
GTEX-1N2DW-0011-R10a-SM-F341J 50-59 years, male 3198.9
GTEX-1RAZS-0011-R10a-SM-F649Y 50-59 years, male 2858.9
GTEX-ZAK1-0011-R10a-SM-H7OGG 50-59 years, female 2371.7
GTEX-11ZU8-0011-R10a-SM-GI4W8 60-69 years, male 2359.4
GTEX-1LC47-0011-R10b-SM-EYYWE 60-69 years, male 2292.6
GTEX-1QMI2-0011-R10a-SM-F3428 60-69 years, male 2134.6
GTEX-1O9I2-0011-R10b-SM-F2I33 50-59 years, male 2131.8
GTEX-15UF6-0011-R10b-SM-9OSVF 70-79 years, female 2037.9
GTEX-139TS-0011-R10a-SM-5K7TU 60-69 years, male 2022.8
GTEX-13JVG-0011-R10b-SM-5KM2P 60-69 years, male 1999.7
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CEREBRAL CORTEX - FANTOM5 CAGEi
Max subtype Scaled Tags Per Millioni 388.6
FANTOM5 sample id Sample description Scaled Tags Per Million
Occipital cortex
Scaled Tags Per Million: 277.7
FF:10163-103B1 76 years, female 277.7
Postcentral gyrus
Scaled Tags Per Million: 315.1
FF:10032-101E5 44-52 years, mixed 315.1
Frontal lobe
Scaled Tags Per Million: 251.9
FF:10040-101F4 32-61 years, mixed 251.9
Insula
Scaled Tags Per Million: 271.5
FF:10039-101F3 20-68 years, mixed 271.5
Medial frontal gyrus
Scaled Tags Per Million: 256.8
FF:10150-102I6 76 years, female 256.8
Medial temporal gyrus
Scaled Tags Per Million: 333.7
FF:10183-103D3 60 years, female 406.0
FF:10156-103A3 76 years, female 261.3
Occipital lobe
Scaled Tags Per Million: 320.1
FF:10076-102A4 27 years, male 320.1
Occipital pole
Scaled Tags Per Million: 319.3
FF:10036-101E9 22-68 years, mixed 319.3
Paracentral gyrus
Scaled Tags Per Million: 233.1
FF:10035-101E8 22-69 years, mixed 233.1
Parietal lobe
Scaled Tags Per Million: 282.5
FF:10171-103B9 60 years, female 325.1
FF:10157-103A4 76 years, female 271.5
FF:10034-101E7 35-89 years, mixed 250.7
Temporal lobe
Scaled Tags Per Million: 388.6
FF:10031-101E4 32-61 years, mixed 388.6

CEREBRAL CORTEX - Macaque RNA-seq
Max subtype nTPMi 146.2
Macaque sample Sample description nTPM
Angular gyrus
nTPM: 117.0
Samples: 1

Max nTPM: 117.0
Min nTPM: 117.0
Sample A 117.0
Claustrum
nTPM: 146.2
Samples: 1

Max nTPM: 146.2
Min nTPM: 146.2
Sample B 146.2
Fusiform gyrus
nTPM: 107.1
Samples: 2

Max nTPM: 120.3
Min nTPM: 93.9
Sample A 93.9
Sample B 120.3
Inferior temporal gyrus
nTPM: 122.7
Samples: 2

Max nTPM: 130.5
Min nTPM: 114.9
Sample A 130.5
Sample B 114.9
Middle temporal gyrus
nTPM: 115.0
Samples: 2

Max nTPM: 137.7
Min nTPM: 92.3
Sample A 137.7
Sample B 92.3
Postcentral gyrus
nTPM: 125.4
Samples: 2

Max nTPM: 135.9
Min nTPM: 114.9
Sample A 114.9
Sample B 135.9
Posterior cingulate cortex
nTPM: 103.5
Samples: 2

Max nTPM: 110.4
Min nTPM: 96.5
Sample A 110.4
Sample B 96.5
Precentral gyrus
nTPM: 114.2
Samples: 3

Max nTPM: 127.1
Min nTPM: 106.9
Sample A 106.9
Sample B 108.5
Sample C 127.1
Superior parietal lobule
nTPM: 106.4
Samples: 2

Max nTPM: 108.4
Min nTPM: 104.4
Sample A 104.4
Sample B 108.4
Superior temporal gyrus
nTPM: 111.4
Samples: 2

Max nTPM: 118.2
Min nTPM: 104.6
Sample A 104.6
Sample B 118.2
Supramarginal gyrus
nTPM: 105.3
Samples: 2

Max nTPM: 116.9
Min nTPM: 93.6
Sample A 93.6
Sample B 116.9
Gyrus rectus
nTPM: 118.4
Samples: 2

Max nTPM: 120.7
Min nTPM: 116.1
Sample A 120.7
Sample B 116.1
Insular cortex
nTPM: 120.9
Samples: 2

Max nTPM: 135.4
Min nTPM: 106.3
Sample A 106.3
Sample B 135.4
Superior frontal gyrus
nTPM: 123.0
Samples: 2

Max nTPM: 133.4
Min nTPM: 112.6
Sample A 112.6
Sample B 133.4

CEREBRAL CORTEX - Pig RNA-seqi
Max subtype nTPMi 320.3
Pig sample Sample description nTPM
Occipital cortex
nTPM: 299.1
Samples: 4

Max nTPM: 366.0
Min nTPM: 266.9
Sample A Female 266.9
Sample B Female 287.8
Sample C Male 366.0
Sample D Male 275.8
Retrosplenial cortex
nTPM: 264.8
Samples: 4

Max nTPM: 293.3
Min nTPM: 234.8
Sample A Female 293.3
Sample B Female 289.8
Sample C Male 241.2
Sample D Male 234.8
Cingulate cortex
nTPM: 265.4
Samples: 4

Max nTPM: 311.1
Min nTPM: 225.6
Sample A Female 296.3
Sample B Female 228.4
Sample C Male 311.1
Sample D Male 225.6
Insular cortex
nTPM: 265.2
Samples: 4

Max nTPM: 317.1
Min nTPM: 201.2
Sample A Female 317.1
Sample B Female 273.0
Sample C Male 269.4
Sample D Male 201.2
Motor cortex
nTPM: 320.3
Samples: 4

Max nTPM: 374.4
Min nTPM: 249.1
Sample A Female 359.3
Sample B Female 298.5
Sample C Male 374.4
Sample D Male 249.1
Prefrontal cortex
nTPM: 281.6
Samples: 4

Max nTPM: 364.9
Min nTPM: 242.2
Sample A Female 364.9
Sample B Female 243.5
Sample C Male 275.7
Sample D Male 242.2
Somatosensory cortex
nTPM: 277.8
Samples: 3

Max nTPM: 294.9
Min nTPM: 246.7
Sample B Female 291.7
Sample C Male 294.9
Sample D Male 246.7
Temporal cortex
nTPM: 273.8
Samples: 3

Max nTPM: 384.7
Min nTPM: 206.5
Sample A Female 384.7
Sample B Female 230.1
Sample D Male 206.5

CEREBRAL CORTEX - Mouse RNA-seqi
Max subtype nTPMi 127.7
Mouse sample Sample description nTPM
Motor and prefrontal cortex
nTPM: 121.7
Samples: 4

Max nTPM: 156.8
Min nTPM: 92.2
Sample A 115.1
Sample B 156.8
Sample C 122.6
Sample D 92.2
Retrosplenial and cingulate cortex
nTPM: 115.1
Samples: 3

Max nTPM: 128.0
Min nTPM: 103.8
Sample A 103.8
Sample B 128.0
Sample C 113.6
Somatosensory cortex
nTPM: 127.7
Samples: 4

Max nTPM: 136.2
Min nTPM: 121.2
Sample A 121.2
Sample B 136.2
Sample C 127.2
Sample D 126.1
Visual cortex
nTPM: 115.1
Samples: 4

Max nTPM: 133.5
Min nTPM: 95.1
Sample A 117.3
Sample B 95.1
Sample C 114.7
Sample D 133.5

CEREBRAL CORTEX - Rat RNA-seq
Max subtype nTPMi 3.4
Rat sample Sample description nTPM
Occipital cortex
nTPM: 3.1
Samples: 4

Max nTPM: 3.6
Min nTPM: 2.2
Sample A 3.4
Sample A 3.6
Sample A 3.0
Sample A 2.2
Retrosplenial and cingulate cortex
nTPM: 3.4
Samples: 4

Max nTPM: 4.1
Min nTPM: 2.3
Sample A 4.1
Sample A 2.3
Sample B 3.9
Sample A 3.3
Somatosensory cortex
nTPM: 3.3
Samples: 4

Max nTPM: 4.7
Min nTPM: 2.1
Sample A 2.5
Sample A 2.1
Sample A 4.0
Sample A 4.7

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