Brain tissue expression of RPL32 in pons

PONS - Expression summary

Protein expressionⁱ

No data

RNA expressionⁱ

HPA Brain:	505.9	nTPM
FANTOM5:	31.6	Scaled Tags Per Million

Mouse:	268.1	nTPM
Pig:	215.7	nTPM

PONS - SINGLE NUCLEI RNA EXPRESSIONⁱ RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right). - UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon - The BAR CHART* shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

SINGLE NUCLEI BRAIN - PONS, NEURONSⁱ

Cell type color

Cluster color

Colored according to cell type group

Read count filter: 0

Cluster		Cell type
	c-1	Excitatory (VGLUT1/2)
	c-2	Excitatory (VGLUT1) ETV1+ Z...
	c-3	Excitatory (VGLUT1/2)
	c-4	Excitatory (VGLUT1) ETV1+ Z...
	c-5	Excitatory (VGLUT1/2)
	c-6	Excitatory (VGLUT1/2)
	c-7	Excitatory (VGLUT1/2)
	c-8	Inhibitory (GAD1/2) SLC6A5+
	c-9	Excitatory (VGLUT2)
	c-10	Excitatory (VGLUT1/2)
	c-11	Excitatory (VGLUT1/2)
	c-12	Unassigned
	c-13	Inhibitory (GAD1/2) RORB+ K
	c-14	Inhibitory (GAD1/2) SST+
	c-15	Excitatory (VGLUT1) ETV1+ Z...
	c-16	Excitatory (VGLUT2)
	c-17	Excitatory (VGLUT1/2)
	c-18	Inhibitory (GAD1/2)
	c-19	Inhibitory (GAD1) PENK+ SST
	c-20	Excitatory (VGLUT2) FOXP2+
	c-21	Excitatory (VGLUT2) LMX1A+
	c-22	Excitatory (VGLUT2) MEIS2+
	c-23	Inhibitory (GAD1/2) SLC6A5+...
	c-24	Inhibitory (GAD1/2) SLC6A5+...
	c-25	Serotonergic SLC6A4+ SLC18A...
	c-26	Inhibitory (GAD1/2) PVALB+ ...
	c-27	Excitatory (VGLUT2)
	c-28	(VGLUT3) PENK+
	c-29	MEIS2+
	c-30	LMX1A+
	c-31	Inhibitory (GAD1/2) TAC1+
	c-32	Excitatory (VGLUT2) PVALB+
	c-33	Inhibitory (GAD1/2) PVALB+ ...
	c-34	Inhibitory (GAD1/2)
	c-35	Excitatory (VGLUT2) SST+ ME...
	c-36	LC Noradrenergic SLC6A2+ SL...
	c-37	Excitatory (VGLUT2) CRH+ FO...
	c-38	Inhibitory (GAD1/2) PVALB+ ...
	c-39	Excitatory (VGLUT2)
	c-40	Excitatory (VGLUT2) PVALB+
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - PONS, NON-NEURONALⁱ

Cell type color

Cluster color

Colored according to cell type group

Read count filter: 0

Cluster		Cell type
	c-1	Oligodendrocytes
	c-2	Oligodendrocytes
	c-3	Oligodendrocyte progenitor ...
	c-4	Oligodendrocytes
	c-5	Oligodendrocytes
	c-6	Oligodendrocytes
	c-7	Microglia
	c-8	Astrocytes
	c-9	Oligodendrocytes
	c-10	Astrocytes (CD44+)
	c-11	Oligodendrocytes
	c-12	Fibroblasts
	c-13	Vascular endothelial cells
	c-14	Pericytes
	c-15	Ependymal cells
	c-16	Lymphocytes
	c-17	Macrophages
	c-18	Microglia (SPP1+ HIF1A+)
	c-19	Bergmann glia
	c-20	Immature oligodendrocytes
	c-21	Oligodendrocyte progenitor ...
	c-22	Vascular smooth muscle cell
	c-23	Monocytes
	c-24	Immature oligodendrocytes
	c-25	Fibroblasts (BNC2+ KCNMA1+ ...
	c-26	Choroid plexus epithelial c...
	c-27	Macrophage Microglia double
	c-28	OPC & lymphocytes doublets
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	505.9

Sample id

Sample description

nTPM

Anterior cochlear nucleus, ventral
nTPM: 505.9

2301	Female, age 85, both hemispheres	583.4
2188	Female, age 91, both hemispheres	549.1
2090	Male, age 80, both hemispheres	529.0
1984	Male, age 76, both hemispheres	362.1

Dorsal cochlear nucleus
nTPM: 467.2

2187	Female, age 91, both hemispheres	524.8
2370	Male, age 61, both hemispheres	495.0
2378	Male, age 80, both hemispheres	484.9
2802	Male, age 74, right hemisphere	471.3
2058	Male, age 76, both hemispheres	360.1

Dorsal tegmental nucleus
nTPM: 471.4

2326	Male, age 74, both hemispheres	516.1
2358	Male, age 61, both hemispheres	499.9
2083	Male, age 80, both hemispheres	482.7
1936	Male, age 76, left hemisphere	387.0

Dorsolateral tegmental area
nTPM: 486.1

2654	Male, age 80, both hemispheres	576.0
2337	Male, age 61, both hemispheres	563.1
2751	Female, age 85, both hemispheres	483.0
2360	Male, age 74, both hemispheres	448.4
2141	Male, age 76, both hemispheres	359.9

Kolliker-Fuse nucleus
nTPM: 492.4

2793	Female, age 91, left hemisphere	533.8
2315	Male, age 76, right hemisphere	498.9
2163	Male, age 80, both hemispheres	444.4

Lateral lemniscal nuclei
nTPM: 394.7

2169	Male, age 76, both hemispheres	432.0
2320	Female, age 91, left hemisphere	420.9
2746	Female, age 85, left hemisphere	396.7
2036	Male, age 80, both hemispheres	381.1
2453	Male, age 74, right hemisphere	343.0

Lateral parabrachial nucleus
nTPM: 496.1

2792	Male, age 76, both hemispheres	633.5
2013	Male, age 80, both hemispheres	550.2
2139	Female, age 85, right hemisphere	413.7
2790	Male, age 61, both hemispheres	387.1

Lateral vestibular nucleus
nTPM: 426.9

2311	Male, age 80, both hemispheres	505.5
2184	Male, age 76, both hemispheres	348.2

Locus coeruleus
nTPM: 380.2

2720	Male, age 74, both hemispheres	486.7
2162	Male, age 80, both hemispheres	436.6
2123	Female, age 91, both hemispheres	399.1
2014	Male, age 55, unknown	378.1
1980	Male, age 76, both hemispheres	334.2
2317	Female, age 72, unknown	329.6
2788	Male, age 74, unknown	296.9

Medial parabrachial nucleus
nTPM: 466.9

2170	Female, age 91, both hemispheres	595.4
2854	Male, age 80, both hemispheres	515.0
2463	Female, age 85, right hemisphere	425.5
2786	Male, age 76, both hemispheres	403.2
2156	Male, age 61, both hemispheres	395.3

Medial periolivary nuclei
nTPM: 392.7

2458	Female, age 91, both hemispheres	436.7
2063	Male, age 76, both hemispheres	428.5
2081	Male, age 80, both hemispheres	412.6
2791	Male, age 74, right hemisphere	359.2
2171	Female, age 85, both hemispheres	326.4

Motor facial nucleus
nTPM: 403.0

2697	Female, age 85, both hemispheres	474.3
2365	Male, age 74, right hemisphere	423.6
2126	Male, age 61, both hemispheres	410.0
2795	Female, age 91, both hemispheres	407.4
2062	Male, age 76, both hemispheres	382.7
2327	Male, age 80, both hemispheres	319.8

Motor trigeminal nucleus
nTPM: 414.0

2321	Female, age 91, both hemispheres	464.2
2560	Male, age 74, both hemispheres	443.2
2335	Male, age 61, both hemispheres	426.4
2309	Male, age 76, both hemispheres	398.2
2079	Male, age 80, both hemispheres	338.0

Nuclei of the trapezoid body
nTPM: 389.5

1983	Male, age 76, both hemispheres	445.4
2166	Male, age 80, both hemispheres	414.7
2159	Male, age 61, both hemispheres	397.0
2368	Female, age 91, both hemispheres	392.7
2735	Female, age 85, both hemispheres	297.5

Nucleus raphe magnus
nTPM: 374.8

2051	Male, age 76, both hemispheres	430.5
2459	Female, age 91, both hemispheres	407.7
2328	Male, age 80, both hemispheres	378.6
2455	Male, age 74, both hemispheres	373.2
2160	Male, age 61, both hemispheres	339.3
2172	Female, age 85, both hemispheres	319.6

Paramedian reticular nucleus
nTPM: 435.9

2052	Male, age 76, both hemispheres	477.4
2313	Male, age 61, both hemispheres	443.6
2050	Female, age 85, both hemispheres	415.9
2057	Male, age 80, both hemispheres	406.6

Pedunculopontine tegmental nucleus
nTPM: 430.7

2338	Male, age 61, both hemispheres	480.8
2334	Male, age 80, both hemispheres	465.9
1921	Female, age 85, both hemispheres	345.2

Pontine nuclei
nTPM: 417.6

2319	Female, age 91, both hemispheres	531.1
2454	Male, age 74, left hemisphere	445.1
1968	Male, age 76, left hemisphere	426.7
1863	Male, age 55, unknown	415.6
2115	Male, age 80, left hemisphere	413.0
2787	Female, age 85, both hemispheres	380.9
2109	Female, age 72, unknown	374.0
2727	Male, age 61, right hemisphere	354.3

Pontine raphe nucleus
nTPM: 382.5

2853	Male, age 76, midline	385.1
2122	Female, age 85, midline	380.0

Posteroventral cochlear nucleus
nTPM: 494.8

2341	Male, age 80, both hemispheres	559.0
2135	Female, age 91, both hemispheres	551.4
2371	Male, age 61, both hemispheres	539.6
2752	Female, age 85, both hemispheres	422.0
2070	Male, age 76, both hemispheres	402.1

Principal sensory trigeminal nucleus
nTPM: 383.4

2367	Female, age 91, left hemisphere	457.7
2158	Male, age 61, both hemispheres	380.8
2324	Male, age 76, both hemispheres	371.3
2008	Male, age 80, left hemisphere	323.8

Reticular pontine nucleus, caudal
nTPM: 409.6

2559	Male, age 74, both hemispheres	473.5
2457	Female, age 91, both hemispheres	434.9
2092	Male, age 76, both hemispheres	427.4
2332	Male, age 80, right hemisphere	302.8

Reticular pontine nucleus, oral
nTPM: 453.9

2366	Female, age 91, both hemispheres	527.3
2167	Male, age 76, both hemispheres	467.8
1939	Male, age 80, both hemispheres	455.2
2361	Male, age 74, both hemispheres	427.6
2012	Female, age 85, both hemispheres	391.7

Reticulotegmental nucleus
nTPM: 416.7

2452	Male, age 74, both hemispheres	478.0
2322	Female, age 91, both hemispheres	426.6
2333	Male, age 80, both hemispheres	399.9
2325	Male, age 76, both hemispheres	362.1

Spinal trigeminal nucleus, oral
nTPM: 371.5

1978	Male, age 76, both hemispheres	388.3
2164	Male, age 80, both hemispheres	382.7
2737	Female, age 85, both hemispheres	343.3

Subcoeruleus area
nTPM: 429.4

2451	Male, age 74, both hemispheres	510.5
2369	Female, age 85, left hemisphere	492.8
2323	Female, age 91, left hemisphere	413.2
1958	Male, age 80, both hemispheres	394.3
2089	Male, age 76, left hemisphere	336.0

Superior olive
nTPM: 416.5

2020	Male, age 76, both hemispheres	483.2
2561	Female, age 91, both hemispheres	454.6
2364	Male, age 74, right hemisphere	436.4
2329	Male, age 80, right hemisphere	361.9
1875	Female, age 85, both hemispheres	346.5

Ventral periolivary nuclei
nTPM: 400.1

2023	Male, age 76, both hemispheres	478.9
2794	Female, age 91, left hemisphere	409.2
2165	Male, age 80, both hemispheres	356.3
2130	Female, age 85, both hemispheres	356.0

Ventrolateral tegmental area, A5 NE cell group
nTPM: 410.7

2840	Female, age 85, both hemispheres	464.5
2456	Female, age 91, both hemispheres	438.1
2161	Male, age 80, both hemispheres	425.6
2359	Male, age 61, both hemispheres	417.8
1959	Male, age 76, both hemispheres	380.3
2449	Male, age 74, both hemispheres	337.9

PONS - FANTOM5 CAGEⁱ

Max subtype Scaled Tags Per Millionⁱ Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.	31.6

FANTOM5 sample id

Sample description

Scaled Tags Per Million

Locus coeruleus
Scaled Tags Per Million: 31.6

FF:10182-103D2	60 years, female	37.3
FF:10165-103B3	76 years, female	25.9

Pons
Scaled Tags Per Million: 29.1

FF:10033-101E6

18-54 years, mixed

29.1

PONS - Pig RNA-seqⁱ

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	215.7

Pig sample

Sample description

nTPM

Pons
nTPM: 215.7

Samples: 3

Max nTPM: 258.8
Min nTPM: 166.7

Sample A	Female	221.6
Sample B	Female	166.7
Sample C	Male	258.8

PONS - Mouse RNA-seqⁱ

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	268.1

Mouse sample

Sample description

nTPM

Pons
nTPM: 268.1

Samples: 4

Max nTPM: 294.6
Min nTPM: 239.1

Sample A		239.1
Sample B		294.6
Sample C		257.6
Sample D		281.1