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BETA
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  • RPL23A
BRAIN MIDBRAIN Show tissue menu
AMYGDALA BASAL GANGLIA CEREBELLUM CEREBRAL CORTEX HIPPOCAMPAL FORMATION HYPOTHALAMUS
MEDULLA OBLONGATA MIDBRAIN PONS SPINAL CORD THALAMUS
ANTIBODIES
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Midbrain
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MIDBRAIN - Expression summary
Protein expressioni

On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.

No data
RNA expressioni

A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.

Scroll down to view mRNA expression data in more detail.

Consensus:1334.9 nTPM
HPA Brain:298.3 nTPM
GTEx:1334.9 nTPM
FANTOM5:9.8 Scaled Tags Per Million
Macaque:1162.1 nTPM
Mouse:1006.3 nTPM
Pig:2422.8 nTPM
MIDBRAIN - SINGLE NUCLEI RNA EXPRESSIONi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.


SINGLE NUCLEI BRAIN - MIDBRAIN, NEURONSi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 90
c-1 Inhibitory (GAD1/2) RORB+ K
c-2 Excitatory (VGLUT1) ETV1+ Z...
c-3 Inhibitory (GAD1/2) RORB+ K
c-4 Inhibitory (GAD1/2) RORB+ K
c-5 Unassigned
c-6 Tectum Excitatory (VGLUT2)
c-7 Inhibitory (GAD1/2)
c-8 Inhibitory (GAD1/2) TFAP2B+
c-9 Excitatory (VGLUT2)
c-10 Excitatory (VGLUT2)
c-11 Tectum Inhibitory (GAD1/2)
c-12 Excitatory (VGLUT2) TFAP2B+
c-13 Excitatory (VGLUT2)
c-14 Excitatory (VGLUT2)
c-15 Tectum Excitatory (VGLUT2)
c-16 Excitatory (VGLUT2)
c-17 Inhibitory (GAD1/2)
c-18 Excitatory (VGLUT2)
c-19 Inhibitory (GAD1/2)
c-20 Inhibitory (GAD1/2)
c-21 Excitatory (VGLUT2)
c-22 Excitatory (VGLUT2)
c-23 Inhibitory (GAD1/2) TFAP2B+
c-24 Inhibitory (GAD1/2)
c-25 Excitatory (VGLUT2) CRH+ CA...
c-26 Inhibitory (GAD1/2) SST+
c-27 Inhibitory (GAD1/2) NPY+
c-28 Inhibitory (GAD1/2) RORB+ K
c-29 Excitatory (VGLUT2) TFAP2B+
c-30 Excitatory (VGLUT2)
c-31 Dopaminergic TH+ LMX1A+ SLC...
c-32 Inhibitory (GAD1/2) PVALB+
c-33 Tegmentum Excitatory (VGLUT...
c-34 Excitatory (VGLUT2) LMX1A+
c-35 Tegmentum Inhibitory (GAD2)...
c-36 TPH2+
c-37 Inhibitory (GAD1/2) CXCL14+
c-38 Excitatory (VGLUT1) SATB2+
c-39 Inhibitory (GAD1/2) RORB+ K
c-40 Excitatory (VGLUT2) MEIS2+
c-41 Inhibitory (GAD1/2) TFAP2B+
c-42 Excitatory (VGLUT2)
c-43 Excitatory (VGLUT1)
c-44 SN Monoaminergic Inhibitory...
c-45 Inhibitory (GAD1/2)
c-46 Excitatory (VGLUT1) GRP+
c-47 Inhibitory (GAD1/2) PVALB+ ...
c-48 Excitatory (VGLUT1)
c-49 Inhibitory (GAD1/2) LAMP5+
c-50 Excitatory (VGLUT2) KIT+
c-51 Excitatory (VGLUT1) SLC5A7+
c-52 Inhibitory (GAD1/2) NOS1+ G...
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - MIDBRAIN, NON-NEURONALi

RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right).

- UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)*100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon

- The BAR CHART shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

Cell type color
Cluster color
Colored according to cell type group
Colored according to clusters
Read count filter: 0
 
Cluster Cell type Expression (nCPM)
0 190
c-1 Oligodendrocytes
c-2 Oligodendrocytes
c-3 Microglia
c-4 Oligodendrocytes
c-5 Oligodendrocyte progenitor ...
c-6 Astrocytes
c-7 Oligodendrocytes
c-8 Oligodendrocytes
c-9 Oligodendrocytes
c-10 Oligodendrocytes
c-11 Oligodendrocytes
c-12 Astrocytes
c-13 Fibroblasts
c-14 NK-cells & T-cells
c-15 Macrophages
c-16 Ependymal cells
c-17 Capillary endothelial cells
c-18 Pericytes
c-19 Oligodendrocyte progenitor ...
c-20 Immature oligodendrocytes
c-21 Vascular smooth muscle cell
c-22 Oligodendrocyte progenitor ...
c-23 B-cells & Monocytes doublet
c-24 Arterial endothelial cells
c-25 CD44+ Mural cells
c-26 Bergmann glia
c-27 Oligodendrocytes & Lymphocy
c-28 Macrophages & Monocytes
Show allShow less
This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

MIDBRAIN - HPA Brain RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

298.3
Sample id Sample description nTPM
Cuneiform nucleus
nTPM: 253.9
2666 Male, age 74, left hemisphere 300.0
1870 Female, age 42, unknown 278.6
2411 Female, age 72, unknown 269.8
2019 Male, age 18, unknown 267.2
2828 Female, age 72, unknown 261.5
2586 Male, age 75, left hemisphere 251.9
1830 Male, age 51, unknown 241.2
1827 Male, age 72, unknown 231.1
1833 Male, age 53, unknown 219.2
2219 Male, age 76, both hemispheres 218.6
Dorsal raphe nucleus
nTPM: 269.6
2298 Female, age 72, unknown 296.1
2750 Male, age 76, both hemispheres 289.5
2016 Female, age 72, unknown 272.2
1828 Male, age 53, unknown 267.2
2047 Male, age 72, unknown 223.0
Inferior colliculus
nTPM: 254.3
2097 Female, age 72, unknown 298.2
1890 Male, age 53, unknown 282.1
1848 Female, age 42, unknown 226.1
2849 Male, age 72, unknown 210.8
Median raphe nucleus
nTPM: 248.6
2220 Male, age 76, midline 248.6
Periaquaductal grey, anterior
nTPM: 265.7
2502 Female, age 75, unknown 334.2
1795 Male, age 51, unknown 231.7
1947 Male, age 18, unknown 231.1
Periaquaductal grey, dorsal
nTPM: 236.1
1840 Male, age 53, unknown 259.1
2464 Female, age 72, unknown 250.2
1831 Male, age 72, unknown 230.4
2850 Male, age 76, both hemispheres 204.7
Periaquaductal grey, lateral
nTPM: 223.7
2053 Male, age 18, unknown 242.8
2140 Male, age 76, both hemispheres 238.7
2272 Male, age 74, both hemispheres 189.7
Pretectal area
nTPM: 235.5
2316 Male, age 76, right hemisphere 312.3
2224 Female, age 72, unknown 266.3
2825 Male, age 18, unknown 249.3
1817 Female, age 42, unknown 244.4
2007 Male, age 72, unknown 240.3
1815 Male, age 53, unknown 239.6
1816 Male, age 51, unknown 234.1
2667 Female, age 75, unknown 205.4
2407 Male, age 75, both hemispheres 202.4
1944 Female, age 72, unknown 200.6
2273 Male, age 74, both hemispheres 195.9
Red nucleus
nTPM: 289.4
2503 Female, age 72, unknown 338.6
1904 Male, age 53, unknown 320.3
1865 Male, age 51, unknown 318.3
1821 Female, age 72, unknown 317.6
2227 Male, age 72, unknown 307.2
2769 Male, age 72, unknown 302.9
2588 Male, age 74, left hemisphere 293.8
1954 Female, age 42, unknown 273.9
2785 Male, age 18, unknown 264.1
2823 Male, age 76, right hemisphere 250.2
2584 Male, age 75, left hemisphere 245.0
2725 Female, age 75, unknown 240.3
Substantia nigra
nTPM: 298.3
1851 Male, age 51, unknown 375.4
2241 Male, age 72, unknown 359.9
2409 Female, age 72, unknown 344.5
2665 Male, age 74, both hemispheres 341.1
2699 Male, age 18, unknown 314.4
1916 Female, age 42, unknown 294.5
2590 Female, age 75, unknown 272.7
1889 Female, age 72, unknown 270.1
1941 Male, age 53, unknown 222.4
2583 Male, age 75, right hemisphere 187.8
Superior colliculus
nTPM: 268.1
2587 Male, age 74, left hemisphere 304.4
2668 Female, age 75, unknown 303.6
1995 Male, age 72, unknown 299.0
1913 Female, age 42, unknown 294.7
1796 Male, age 53, unknown 272.2
2087 Female, age 72, unknown 262.3
2261 Male, age 18, unknown 247.3
2664 Male, age 75, both hemispheres 234.0
1839 Male, age 51, unknown 231.9
1895 Male, age 76, right hemisphere 231.5
Ventral tegmental area
nTPM: 280.6
1915 Female, age 42, unknown 324.5
2223 Female, age 72, unknown 304.8
2021 Male, age 53, unknown 293.5
2410 Female, age 72, unknown 270.6
1942 Male, age 51, unknown 265.4
2218 Male, age 76, both hemispheres 224.7

MIDBRAIN - GTEx RNA-seqi

RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.

Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1334.9
GTEx sample id Sample description nTPM
Brain - Substantia nigra
Average nTPM: 1334.9
Samples: 183

Max nTPM: 3048.1
Min nTPM: 453.3
Std nTPM: 465.7
Median nTPM: 1237.5
GTEX-1LVA9-0011-R2a-SM-EZ6MJ 50-59 years, male 3048.1
GTEX-1F75B-0011-R2a-SM-ARL8I 50-59 years, male 2890.8
GTEX-1IGQW-0011-R2b-SM-D4P26 60-69 years, male 2839.1
GTEX-1RLM8-0011-R2a-SM-EZ6N4 50-59 years, male 2561.2
GTEX-11GS4-0011-R2a-SM-DO942 60-69 years, male 2492.1
GTEX-1I19N-0011-R2b-SM-GPRYG 70-79 years, male 2399.0
GTEX-ZV68-0011-R2a-SM-4YCDK 50-59 years, female 2355.7
GTEX-1H1ZS-0011-R2b-SM-CL54Q 70-79 years, male 2247.1
GTEX-1A8G7-0011-R2a-SM-7IGQI 60-69 years, male 2227.9
GTEX-1MCQQ-0011-R2a-SM-F649V 60-69 years, male 2200.4
GTEX-1HBPH-0011-R2a-SM-GQ1DS 40-49 years, female 2199.1
GTEX-1N5O9-0011-R2a-SM-G8LM1 60-69 years, male 2116.1
GTEX-1C6VR-0011-R2a-SM-7RHGZ 60-69 years, male 2107.1
GTEX-1EU9M-0011-R2b-SM-9QEH7 60-69 years, male 2029.8
GTEX-12ZZX-0011-R2a-SM-5EGLG 40-49 years, female 2027.2
GTEX-1117F-0011-R2b-SM-GI4VL 60-69 years, female 2000.8
GTEX-R55E-0011-R2A-SM-EYYV9 20-29 years, male 1955.1
GTEX-YJ89-0011-R2b-SM-4RGLT 60-69 years, male 1931.8
GTEX-12WSH-0011-R2a-SM-5GU68 50-59 years, male 1926.7
GTEX-1R9K4-0011-R2b-SM-G8LLF 60-69 years, male 1895.3
GTEX-1O9I2-0011-R2b-SM-F3K53 50-59 years, male 1882.2
GTEX-1HR98-0011-R2a-SM-ARL7A 60-69 years, male 1847.6
GTEX-1LG7Y-0011-R2b-SM-G8LMM 50-59 years, male 1837.5
GTEX-1GZ2Q-0011-R2b-SM-9OSWO 40-49 years, male 1828.4
GTEX-1E1VI-0011-R2a-SM-9QEGS 50-59 years, male 1827.9
GTEX-ZAJG-0011-R2a-SM-GNTAX 50-59 years, female 1825.0
GTEX-1PWST-0011-R2b-SM-F3K5I 70-79 years, male 1807.5
GTEX-RN5K-0011-R2A-SM-GQ1CA 50-59 years, female 1802.7
GTEX-13OVJ-0011-R2b-SM-5L3GP 50-59 years, female 1785.7
GTEX-1LVAO-0011-R2a-SM-EYYX1 60-69 years, male 1762.9
GTEX-1JMQJ-0011-R2a-SM-F6493 50-59 years, male 1757.7
GTEX-131XH-0011-R2b-SM-5DUVY 50-59 years, male 1736.5
GTEX-139TS-0011-R2b-SM-5J1MX 60-69 years, male 1705.3
GTEX-ZE9C-0011-R2a-SM-4WKGH 60-69 years, male 1694.7
GTEX-1JMQK-0011-R2a-SM-EYYXQ 60-69 years, male 1675.9
GTEX-1KD5A-0011-R2b-SM-G9EPP 50-59 years, male 1675.0
GTEX-13SLW-0011-R2b-SM-5O9C6 70-79 years, male 1670.3
GTEX-1GN2E-0011-R2a-SM-9WG7D 60-69 years, male 1648.2
GTEX-11TUW-0011-R2b-SM-DO92T 60-69 years, male 1638.8
GTEX-1LB8K-0011-R2a-SM-EZ6MQ 50-59 years, male 1636.0
GTEX-1NV5F-0011-R2a-SM-G8LME 60-69 years, female 1628.2
GTEX-13NYB-0011-R2a-SM-5MR3C 40-49 years, male 1621.2
GTEX-1LSNL-0011-R2a-SM-EZ6MK 50-59 years, male 1614.0
GTEX-1IDJH-0011-R2a-SM-GPI9D 70-79 years, male 1609.0
GTEX-1H3VE-0011-R2a-SM-CE6SA 40-49 years, male 1590.1
GTEX-1H3O1-0011-R2b-SM-CKZOT 60-69 years, male 1589.0
GTEX-1IY9M-0011-R2a-SM-D4P29 60-69 years, male 1581.7
GTEX-1LKK1-0011-R2b-SM-G8OLT 50-59 years, female 1545.8
GTEX-12WSA-0011-R2a-SM-57WDK 60-69 years, male 1545.7
GTEX-15SHU-0011-R2a-SM-GPRXS 40-49 years, female 1544.6
GTEX-1LSVX-0011-R2a-SM-G8OL9 60-69 years, male 1540.8
GTEX-12WSD-0011-R2a-SM-5LZWB 60-69 years, female 1533.3
GTEX-1NV8Z-0011-R2b-SM-F648N 60-69 years, male 1530.6
GTEX-1GTWX-0011-R2b-SM-ADEH5 60-69 years, male 1527.0
GTEX-1QMI2-0011-R2b-SM-F648R 60-69 years, male 1514.3
GTEX-12WSF-0011-R2a-SM-5DUVU 70-79 years, male 1504.4
GTEX-1J8Q2-0011-R2b-SM-EAZ2X 60-69 years, male 1500.7
GTEX-1GN1U-0011-R2a-SM-CL53A 50-59 years, female 1494.1
GTEX-1I1GS-0011-R2b-SM-CMKHG 60-69 years, male 1488.5
GTEX-17HG3-0011-R2a-SM-7MGVX 30-39 years, female 1488.4
GTEX-XMD1-0011-R2B-SM-4AT5N 60-69 years, male 1488.4
GTEX-13CF2-0011-R2a-SM-5L3DC 60-69 years, male 1486.3
GTEX-1MA7X-0011-R2b-SM-EZ6MT 60-69 years, male 1483.1
GTEX-11EMC-0011-R2b-SM-DO114 60-69 years, female 1482.7
GTEX-1IL2U-0011-R2a-SM-ARU6V 60-69 years, male 1477.7
GTEX-1I1CD-0011-R2a-SM-CM2T3 60-69 years, female 1471.1
GTEX-1J1OQ-0011-R2b-SM-ARU88 40-49 years, female 1466.4
GTEX-13OVL-0011-R2b-SM-H65ZN 50-59 years, male 1465.5
GTEX-ZDXO-0011-R2b-SM-4WKFG 60-69 years, male 1462.1
GTEX-1F6IF-0011-R2b-SM-9QEHB 60-69 years, male 1453.3
GTEX-OHPN-0011-R2A-SM-2I5FB 60-69 years, female 1451.0
GTEX-13PDP-0011-R2b-SM-5O9DH 60-69 years, male 1446.0
GTEX-17EVP-0011-R2a-SM-7LG4W 40-49 years, male 1429.4
GTEX-14BIM-0011-R2b-SM-69LQ6 60-69 years, female 1419.8
GTEX-1JJ6O-0011-R2a-SM-EY5ZO 60-69 years, male 1419.8
GTEX-1KD4Q-0011-R2a-SM-F649I 40-49 years, male 1419.1
GTEX-15G19-0011-R2b-SM-H6Q7S 60-69 years, male 1397.2
GTEX-1JN1M-0011-R2b-SM-G9EPE 60-69 years, female 1393.2
GTEX-13O3Q-0011-R2b-SM-5KM3K 50-59 years, male 1372.1
GTEX-1399T-0011-R2b-SM-5DUXM 60-69 years, male 1368.1
GTEX-1JMPZ-0011-R2a-SM-G8LLS 30-39 years, male 1351.1
GTEX-1N2EE-0011-R2a-SM-F649F 60-69 years, male 1348.1
GTEX-1F48J-0011-R2a-SM-CL535 50-59 years, female 1347.6
GTEX-1KWVE-0011-R2a-SM-G8OLX 30-39 years, male 1330.4
GTEX-1H1DG-0011-R2a-SM-ADEIQ 70-79 years, male 1326.9
GTEX-1192X-0011-R2b-SM-GI4VV 50-59 years, male 1325.1
GTEX-1POEN-0011-R2b-SM-G8LLP 30-39 years, female 1287.5
GTEX-13FXS-0011-R2b-SM-5K7XX 50-59 years, male 1279.1
GTEX-13G51-0011-R2b-SM-5LZXS 60-69 years, male 1269.6
GTEX-11WQC-0011-R2a-SM-DO927 60-69 years, male 1264.3
GTEX-YFC4-0011-R2a-SM-4V6DZ 40-49 years, female 1242.1
GTEX-132Q8-0011-R2b-SM-5EQ5Z 60-69 years, male 1237.5
GTEX-15EO6-0011-R2a-SM-6M46R 50-59 years, male 1231.6
GTEX-1HSMO-0011-R2a-SM-CL553 60-69 years, male 1229.4
GTEX-147GR-0011-R2b-SM-5S2RQ 60-69 years, male 1226.7
GTEX-ZYY3-0011-R2a-SM-GNTB2 60-69 years, female 1223.3
GTEX-1R9PO-0011-R2a-SM-F2TBH 60-69 years, female 1216.2
GTEX-1GMR8-0011-R2a-SM-CE6RD 50-59 years, female 1214.5
GTEX-1H23P-0011-R2a-SM-CKZP3 60-69 years, male 1214.0
GTEX-11UD1-0011-R2b-SM-5BC6O 40-49 years, female 1203.4
GTEX-15DCD-0011-R2b-SM-6LPIE 70-79 years, female 1199.4
GTEX-NPJ7-0011-R2a-SM-2I3GF 60-69 years, female 1199.4
GTEX-16Z82-0011-R2b-SM-79OK9 60-69 years, male 1193.0
GTEX-ZAK1-0011-R2a-SM-GPRX1 50-59 years, female 1187.9
GTEX-1CB4G-0011-R2a-SM-9QEGQ 60-69 years, male 1187.8
GTEX-13O3O-0011-R2b-SM-5P9H1 60-69 years, female 1182.2
GTEX-11PRG-0011-R2a-SM-69LQ5 50-59 years, male 1180.2
GTEX-14C5O-0011-R2a-SM-5ZZV2 60-69 years, male 1178.2
GTEX-1HT8W-0011-R2a-SM-CMKH9 30-39 years, male 1172.1
GTEX-13N2G-0011-R2a-SM-5MR4Q 60-69 years, male 1145.1
GTEX-15RJE-0011-R2b-SM-79OMP 40-49 years, male 1141.6
GTEX-1CB4J-0011-R2a-SM-9WG5N 60-69 years, male 1140.1
GTEX-13X6K-0011-R2b-SM-5P9K3 60-69 years, female 1139.8
GTEX-1EMGI-0011-R2b-SM-9OSVS 60-69 years, male 1136.8
GTEX-1B8SG-0011-R2b-SM-79OOT 50-59 years, male 1133.3
GTEX-1RDX4-0011-R2b-SM-F649Z 50-59 years, female 1131.7
GTEX-1445S-0011-R2b-SM-5PNUH 60-69 years, male 1102.0
GTEX-11ZTS-0011-R2b-SM-5BC75 60-69 years, female 1099.9
GTEX-11TTK-0011-R2b-SM-GJ3PU 60-69 years, female 1099.0
GTEX-1RQED-0011-R2a-SM-F3K5T 60-69 years, male 1096.3
GTEX-16GPK-0011-R2a-SM-GRR1F 60-69 years, male 1093.0
GTEX-13SLX-0011-R2b-SM-5S2VP 50-59 years, female 1078.3
GTEX-14ASI-0011-R2b-SM-5YY9H 60-69 years, male 1068.8
GTEX-XLM4-0011-R2B-SM-4AT5Z 60-69 years, male 1067.5
GTEX-11GSP-0011-R2b-SM-9QEGE 60-69 years, female 1062.0
GTEX-UTHO-0011-R2A-SM-3GIKC 60-69 years, male 1059.5
GTEX-13X6I-0011-R2b-SM-5PNWQ 60-69 years, male 1058.9
GTEX-T2IS-0011-R2A-SM-32QPF 20-29 years, female 1056.8
GTEX-1F6I4-0011-R2a-SM-CL536 60-69 years, male 1049.9
GTEX-14PJO-0011-R2a-SM-5ZZVF 60-69 years, male 1042.9
GTEX-14JG1-0011-R2a-SM-5ZZVE 40-49 years, male 1029.4
GTEX-145LS-0011-R2a-SM-5PNZI 60-69 years, female 1012.9
GTEX-T6MN-0011-R2A-SM-32QOW 50-59 years, male 1010.3
GTEX-1HFI6-0011-R2a-SM-CMKH5 40-49 years, male 1007.9
GTEX-1EKGG-0011-R2a-SM-CE6R8 60-69 years, male 1006.8
GTEX-1313W-0011-R2a-SM-5EGLF 50-59 years, female 1004.0
GTEX-14PN4-0011-R2a-SM-6EU2Y 50-59 years, male 1000.8
GTEX-11GSO-0011-R2a-SM-57WDF 60-69 years, male 988.5
GTEX-13NYS-0011-R2b-SM-5MR4G 60-69 years, male 985.9
GTEX-1B933-0011-R2b-SM-7IGNM 50-59 years, female 956.9
GTEX-1A3MX-0011-R2b-SM-7EWFL 60-69 years, male 951.3
GTEX-1P4AB-0011-R2a-SM-F649K 50-59 years, male 941.5
GTEX-1N2EF-0011-R2b-SM-F6482 60-69 years, male 941.4
GTEX-117XS-0011-R2b-SM-GI4VT 60-69 years, male 939.1
GTEX-1RQEC-0011-R2b-SM-EY5ZT 60-69 years, male 938.2
GTEX-15DYW-0011-R2b-SM-7KUKY 60-69 years, female 927.3
GTEX-ZAB4-0011-R2a-SM-4RGNP 40-49 years, male 924.9
GTEX-11NUK-0011-R2a-SM-GINAO 50-59 years, male 922.2
GTEX-1HB9E-0011-R2b-SM-A96RW 50-59 years, male 907.2
GTEX-1B996-0011-R2a-SM-7IGON 60-69 years, male 892.1
GTEX-1GN73-0011-R2a-SM-CJI2V 60-69 years, male 883.0
GTEX-1PPGY-0011-R2b-SM-F33YW 60-69 years, male 882.1
GTEX-QVJO-0011-R2A-SM-2S1QK 60-69 years, female 881.9
GTEX-13QJC-0011-R2b-SM-5PNUN 60-69 years, female 878.6
GTEX-X4XX-0011-R2A-SM-3P623 60-69 years, male 875.5
GTEX-111FC-0011-R2a-SM-GIN8S 60-69 years, male 871.2
GTEX-14BIN-0011-R2a-SM-5S2RJ 50-59 years, female 870.8
GTEX-WL46-0011-R2A-SM-3LK6O 50-59 years, male 866.3
GTEX-WHSE-0011-R2A-SM-3P5ZL 20-29 years, male 859.4
GTEX-13OW8-0011-R2a-SM-5L3G2 60-69 years, male 859.2
GTEX-X585-0011-R2B-SM-46MVF 50-59 years, male 858.3
GTEX-1MJK2-0011-R2b-SM-EXUS5 50-59 years, male 852.6
GTEX-ZZPT-0011-R2a-SM-GNTB1 50-59 years, male 848.9
GTEX-QMR6-0011-R2A-SM-32PKV 50-59 years, male 840.7
GTEX-11DZ1-0011-R2a-SM-DNZZM 50-59 years, male 835.9
GTEX-S7SE-0011-R2A-SM-2XCDC 50-59 years, male 826.1
GTEX-13RTJ-0011-R2a-SM-5PNW9 60-69 years, male 824.7
GTEX-1PIIG-0011-R2b-SM-F648W 30-39 years, male 824.2
GTEX-12696-0011-R2b-SM-GHWPY 60-69 years, male 808.9
GTEX-13OW6-0011-R2a-SM-5L3HG 50-59 years, male 795.1
GTEX-1I1GV-0011-R2a-SM-ARZLF 60-69 years, male 765.8
GTEX-Q2AG-0011-R2A-SM-2HMIT 40-49 years, female 750.7
GTEX-1LH75-0011-R2b-SM-EYYWQ 50-59 years, female 729.6
GTEX-1IKJJ-0011-R2b-SM-ARZLJ 60-69 years, male 726.9
GTEX-RU72-0011-R2A-SM-2TF6O 50-59 years, female 722.3
GTEX-QDT8-0011-R2A-SM-32PKQ 30-39 years, female 705.7
GTEX-13OW7-0011-R2b-SM-H6Q8E 50-59 years, male 678.2
GTEX-X4EP-0011-R2B-SM-3P625 60-69 years, female 678.1
GTEX-Z93S-0011-R2a-SM-4RGNG 50-59 years, male 646.5
GTEX-1B8L1-0011-R2a-SM-9OSVL 60-69 years, male 638.6
GTEX-15CHQ-0011-R2b-SM-6AJAD 60-69 years, male 611.1
GTEX-15ER7-0011-R2a-SM-6M46O 20-29 years, female 454.1
GTEX-WVLH-0011-R2A-SM-3MJFJ 50-59 years, male 453.3
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MIDBRAIN - FANTOM5 CAGEi

RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.

Max subtype Scaled Tags Per Millioni

Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.

9.8
FANTOM5 sample id Sample description Scaled Tags Per Million
Substantia nigra
Scaled Tags Per Million: 9.8
FF:10158-103A5 76 years, female 9.8

MIDBRAIN - Macaque RNA-seq
Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1162.1
Macaque sample Sample description nTPM
Substantia nigra
nTPM: 1162.1
Samples: 1

Max nTPM: 1162.1
Min nTPM: 1162.1
Sample A 1162.1
Midbrain
nTPM: 759.0
Samples: 1

Max nTPM: 759.0
Min nTPM: 759.0
Sample A 759.0
Superior colliculi
nTPM: 586.3
Samples: 1

Max nTPM: 586.3
Min nTPM: 586.3
Sample A 586.3

MIDBRAIN - Pig RNA-seqi

RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

2422.8
Pig sample Sample description nTPM
Substantia nigra
nTPM: 2422.8
Samples: 3

Max nTPM: 2696.7
Min nTPM: 2186.3
Sample A Female 2696.7
Sample B Female 2385.5
Sample C Male 2186.3
Midbrain
nTPM: 2032.8
Samples: 3

Max nTPM: 2526.4
Min nTPM: 1770.6
Sample B Female 2526.4
Sample C Male 1801.4
Sample D Male 1770.6
Periaqueductal gray
nTPM: 2028.1
Samples: 3

Max nTPM: 2191.5
Min nTPM: 1946.1
Sample B Female 1946.6
Sample C Male 2191.5
Sample D Male 1946.1
Superior colliculi
nTPM: 2274.5
Samples: 4

Max nTPM: 2878.2
Min nTPM: 1804.3
Sample A Female 2878.2
Sample B Female 1804.3
Sample C Male 2230.3
Sample D Male 2185.3

MIDBRAIN - Mouse RNA-seqi

RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.

Max subtype nTPMi

Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.

1006.3
Mouse sample Sample description nTPM
Midbrain
nTPM: 1006.3
Samples: 4

Max nTPM: 1086.6
Min nTPM: 960.1
Sample A 1086.6
Sample B 981.6
Sample C 960.1
Sample D 996.9

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