Brain tissue expression of SELENOP in pons

PONS - Expression summary

Protein expressionⁱ

No data

RNA expressionⁱ

HPA Brain:	534.0	nTPM
FANTOM5:	1222.8	Scaled Tags Per Million

Mouse:	135.7	nTPM
Rat:	339.6	nTPM

PONS - SINGLE NUCLEI RNA EXPRESSIONⁱ RNA expression in the single nuclei cluster types identified in this brain region visualized by a UMAP plot (top) and a bar chart (to the right). - UMAP PLOT visualizes the cells in each cluster; where each dot corresponds to a cell. For each individual cell, mouseover reveals read count and which cluster the cell belongs to. Hovering over a cluster name will highlight the corresponding cluster in the bar chart two the right. There are 2 options for color schemes: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster. There are 3 options for cell intensities: 1) Intensity, which color the individual cells according to % of max (log2(read_count+1)/log2(max(read_count)+1)100) in five different bins (<1%,<25%,<50%,<75%,≥75%) 2) Interval, which color the individual cells according to fixed interval of read count (0,1,2-4,5-9,>10) 3) Hexagon, which color the hexagon on average read count of all cells inside the hexagon - The BAR CHART* shows RNA expression (nTPM) in each cluster type. Hovering over the cluster name reveals nTPM value and number of included cells. Hovering over a bar highlights the corresponding cluster in the UMAP plot above. Color-coding can be toggled on the top of the page, between 2 options: 1) cell type color, which is based on cell type groups used in the Single cell type part of the Single cell resource and 2) cluster color, which assigns a unique color to each cluster.

SINGLE NUCLEI BRAIN - PONS, NEURONSⁱ

Cell type color

Cluster color

Colored according to cell type group

Read count filter: 0

Cluster		Cell type
	c-1	Excitatory (VGLUT1/2)
	c-2	Excitatory (VGLUT1) ETV1+ Z...
	c-3	Excitatory (VGLUT1/2)
	c-4	Excitatory (VGLUT1) ETV1+ Z...
	c-5	Excitatory (VGLUT1/2)
	c-6	Excitatory (VGLUT1/2)
	c-7	Excitatory (VGLUT1/2)
	c-8	Inhibitory (GAD1/2) SLC6A5+
	c-9	Excitatory (VGLUT2)
	c-10	Excitatory (VGLUT1/2)
	c-11	Excitatory (VGLUT1/2)
	c-12	Unassigned
	c-13	Inhibitory (GAD1/2) RORB+ K
	c-14	Inhibitory (GAD1/2) SST+
	c-15	Excitatory (VGLUT1) ETV1+ Z...
	c-16	Excitatory (VGLUT2)
	c-17	Excitatory (VGLUT1/2)
	c-18	Inhibitory (GAD1/2)
	c-19	Inhibitory (GAD1) PENK+ SST
	c-20	Excitatory (VGLUT2) FOXP2+
	c-21	Excitatory (VGLUT2) LMX1A+
	c-22	Excitatory (VGLUT2) MEIS2+
	c-23	Inhibitory (GAD1/2) SLC6A5+...
	c-24	Inhibitory (GAD1/2) SLC6A5+...
	c-25	Serotonergic SLC6A4+ SLC18A...
	c-26	Inhibitory (GAD1/2) PVALB+ ...
	c-27	Excitatory (VGLUT2)
	c-28	(VGLUT3) PENK+
	c-29	MEIS2+
	c-30	LMX1A+
	c-31	Inhibitory (GAD1/2) TAC1+
	c-32	Excitatory (VGLUT2) PVALB+
	c-33	Inhibitory (GAD1/2) PVALB+ ...
	c-34	Inhibitory (GAD1/2)
	c-35	Excitatory (VGLUT2) SST+ ME...
	c-36	LC Noradrenergic SLC6A2+ SL...
	c-37	Excitatory (VGLUT2) CRH+ FO...
	c-38	Inhibitory (GAD1/2) PVALB+ ...
	c-39	Excitatory (VGLUT2)
	c-40	Excitatory (VGLUT2) PVALB+
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

SINGLE NUCLEI BRAIN - PONS, NON-NEURONALⁱ

Cell type color

Cluster color

Colored according to cell type group

Read count filter: 0

Cluster		Cell type
	c-1	Oligodendrocytes
	c-2	Oligodendrocytes
	c-3	Oligodendrocyte progenitor ...
	c-4	Oligodendrocytes
	c-5	Oligodendrocytes
	c-6	Oligodendrocytes
	c-7	Microglia
	c-8	Astrocytes
	c-9	Oligodendrocytes
	c-10	Astrocytes (CD44+)
	c-11	Oligodendrocytes
	c-12	Fibroblasts
	c-13	Vascular endothelial cells
	c-14	Pericytes
	c-15	Ependymal cells
	c-16	Lymphocytes
	c-17	Macrophages
	c-18	Microglia (SPP1+ HIF1A+)
	c-19	Bergmann glia
	c-20	Immature oligodendrocytes
	c-21	Oligodendrocyte progenitor ...
	c-22	Vascular smooth muscle cell
	c-23	Monocytes
	c-24	Immature oligodendrocytes
	c-25	Fibroblasts (BNC2+ KCNMA1+ ...
	c-26	Choroid plexus epithelial c...
	c-27	Macrophage Microglia double
	c-28	OPC & lymphocytes doublets
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This data was generated by Siletti K et al. (2023), re-processed by HPA (see methods) and simplified for global overview

PONS - HPA Brain Stereo-seq

PONS - HPA Brain RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	534.0

Sample id

Sample description

nTPM

Anterior cochlear nucleus, ventral
nTPM: 534.0

2090	Male, age 80, both hemispheres	688.2
2188	Female, age 91, both hemispheres	556.4
2301	Female, age 85, both hemispheres	515.1
1984	Male, age 76, both hemispheres	376.4

Dorsal cochlear nucleus
nTPM: 399.5

2187	Female, age 91, both hemispheres	626.1
2378	Male, age 80, both hemispheres	458.5
2058	Male, age 76, both hemispheres	345.2
2370	Male, age 61, both hemispheres	288.5
2802	Male, age 74, right hemisphere	279.0

Dorsal tegmental nucleus
nTPM: 390.9

2083	Male, age 80, both hemispheres	591.5
2326	Male, age 74, both hemispheres	412.1
1936	Male, age 76, left hemisphere	327.1
2358	Male, age 61, both hemispheres	232.7

Dorsolateral tegmental area
nTPM: 476.6

2751	Female, age 85, both hemispheres	730.9
2654	Male, age 80, both hemispheres	585.3
2337	Male, age 61, both hemispheres	565.9
2360	Male, age 74, both hemispheres	290.2
2141	Male, age 76, both hemispheres	210.8

Kolliker-Fuse nucleus
nTPM: 434.9

2793	Female, age 91, left hemisphere	452.7
2315	Male, age 76, right hemisphere	443.1
2163	Male, age 80, both hemispheres	408.9

Lateral lemniscal nuclei
nTPM: 376.9

2746	Female, age 85, left hemisphere	414.1
2320	Female, age 91, left hemisphere	410.3
2036	Male, age 80, both hemispheres	367.4
2453	Male, age 74, right hemisphere	358.3
2169	Male, age 76, both hemispheres	334.2

Lateral parabrachial nucleus
nTPM: 427.3

2792	Male, age 76, both hemispheres	575.5
2013	Male, age 80, both hemispheres	500.3
2139	Female, age 85, right hemisphere	350.2
2790	Male, age 61, both hemispheres	283.3

Lateral vestibular nucleus
nTPM: 475.5

2311	Male, age 80, both hemispheres	616.8
2184	Male, age 76, both hemispheres	334.1

Locus coeruleus
nTPM: 199.2

2162	Male, age 80, both hemispheres	273.3
2123	Female, age 91, both hemispheres	218.9
2317	Female, age 72, unknown	210.7
2720	Male, age 74, both hemispheres	197.0
2788	Male, age 74, unknown	183.2
2014	Male, age 55, unknown	170.1
1980	Male, age 76, both hemispheres	141.2

Medial parabrachial nucleus
nTPM: 510.9

2170	Female, age 91, both hemispheres	794.0
2463	Female, age 85, right hemisphere	611.1
2854	Male, age 80, both hemispheres	505.9
2786	Male, age 76, both hemispheres	390.4
2156	Male, age 61, both hemispheres	253.4

Medial periolivary nuclei
nTPM: 441.1

2081	Male, age 80, both hemispheres	604.1
2791	Male, age 74, right hemisphere	481.2
2458	Female, age 91, both hemispheres	466.7
2063	Male, age 76, both hemispheres	399.7
2171	Female, age 85, both hemispheres	254.0

Motor facial nucleus
nTPM: 404.8

2126	Male, age 61, both hemispheres	591.2
2365	Male, age 74, right hemisphere	538.3
2795	Female, age 91, both hemispheres	367.8
2697	Female, age 85, both hemispheres	354.6
2062	Male, age 76, both hemispheres	308.5
2327	Male, age 80, both hemispheres	268.3

Motor trigeminal nucleus
nTPM: 383.2

2560	Male, age 74, both hemispheres	473.9
2321	Female, age 91, both hemispheres	441.3
2309	Male, age 76, both hemispheres	358.0
2079	Male, age 80, both hemispheres	327.3
2335	Male, age 61, both hemispheres	315.2

Nuclei of the trapezoid body
nTPM: 347.4

2368	Female, age 91, both hemispheres	437.2
2166	Male, age 80, both hemispheres	430.8
1983	Male, age 76, both hemispheres	334.9
2159	Male, age 61, both hemispheres	312.8
2735	Female, age 85, both hemispheres	221.5

Nucleus raphe magnus
nTPM: 350.1

2459	Female, age 91, both hemispheres	539.8
2051	Male, age 76, both hemispheres	460.3
2328	Male, age 80, both hemispheres	382.9
2455	Male, age 74, both hemispheres	338.1
2160	Male, age 61, both hemispheres	217.8
2172	Female, age 85, both hemispheres	161.9

Paramedian reticular nucleus
nTPM: 476.3

2052	Male, age 76, both hemispheres	621.3
2057	Male, age 80, both hemispheres	597.2
2050	Female, age 85, both hemispheres	401.8
2313	Male, age 61, both hemispheres	284.9

Pedunculopontine tegmental nucleus
nTPM: 392.7

2338	Male, age 61, both hemispheres	494.3
2334	Male, age 80, both hemispheres	413.6
1921	Female, age 85, both hemispheres	270.2

Pontine nuclei
nTPM: 434.5

2454	Male, age 74, left hemisphere	707.2
2109	Female, age 72, unknown	555.0
2319	Female, age 91, both hemispheres	461.3
2115	Male, age 80, left hemisphere	438.5
1968	Male, age 76, left hemisphere	398.3
1863	Male, age 55, unknown	379.8
2727	Male, age 61, right hemisphere	332.1
2787	Female, age 85, both hemispheres	203.5

Pontine raphe nucleus
nTPM: 269.6

2853	Male, age 76, midline	276.8
2122	Female, age 85, midline	262.4

Posteroventral cochlear nucleus
nTPM: 503.5

2341	Male, age 80, both hemispheres	813.1
2135	Female, age 91, both hemispheres	538.3
2070	Male, age 76, both hemispheres	488.5
2752	Female, age 85, both hemispheres	340.3
2371	Male, age 61, both hemispheres	337.4

Principal sensory trigeminal nucleus
nTPM: 359.4

2367	Female, age 91, left hemisphere	534.7
2324	Male, age 76, both hemispheres	315.7
2008	Male, age 80, left hemisphere	309.4
2158	Male, age 61, both hemispheres	277.9

Reticular pontine nucleus, caudal
nTPM: 484.1

2457	Female, age 91, both hemispheres	635.0
2559	Male, age 74, both hemispheres	532.9
2092	Male, age 76, both hemispheres	468.0
2332	Male, age 80, right hemisphere	300.3

Reticular pontine nucleus, oral
nTPM: 520.9

2361	Male, age 74, both hemispheres	798.6
1939	Male, age 80, both hemispheres	508.0
2167	Male, age 76, both hemispheres	471.0
2366	Female, age 91, both hemispheres	415.3
2012	Female, age 85, both hemispheres	411.6

Reticulotegmental nucleus
nTPM: 353.2

2322	Female, age 91, both hemispheres	473.7
2333	Male, age 80, both hemispheres	393.7
2452	Male, age 74, both hemispheres	323.5
2325	Male, age 76, both hemispheres	221.9

Spinal trigeminal nucleus, oral
nTPM: 355.1

2164	Male, age 80, both hemispheres	439.1
1978	Male, age 76, both hemispheres	336.7
2737	Female, age 85, both hemispheres	289.4

Subcoeruleus area
nTPM: 389.4

2369	Female, age 85, left hemisphere	776.7
1958	Male, age 80, both hemispheres	403.0
2089	Male, age 76, left hemisphere	323.6
2451	Male, age 74, both hemispheres	225.3
2323	Female, age 91, left hemisphere	218.4

Superior olive
nTPM: 436.6

2364	Male, age 74, right hemisphere	587.6
2020	Male, age 76, both hemispheres	439.1
2329	Male, age 80, right hemisphere	433.4
2561	Female, age 91, both hemispheres	396.6
1875	Female, age 85, both hemispheres	326.6

Ventral periolivary nuclei
nTPM: 322.5

2023	Male, age 76, both hemispheres	495.1
2165	Male, age 80, both hemispheres	373.4
2794	Female, age 91, left hemisphere	215.3
2130	Female, age 85, both hemispheres	206.4

Ventrolateral tegmental area, A5 NE cell group
nTPM: 460.1

2456	Female, age 91, both hemispheres	568.0
2359	Male, age 61, both hemispheres	528.5
2161	Male, age 80, both hemispheres	476.0
2449	Male, age 74, both hemispheres	438.4
2840	Female, age 85, both hemispheres	406.4
1959	Male, age 76, both hemispheres	343.6

PONS - FANTOM5 CAGEⁱ

Max subtype Scaled Tags Per Millionⁱ Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.	1222.8

FANTOM5 sample id

Sample description

Scaled Tags Per Million

Locus coeruleus
Scaled Tags Per Million: 1222.8

FF:10165-103B3	76 years, female	1547.6
FF:10182-103D2	60 years, female	898.0

Pons
Scaled Tags Per Million: 1031.3

FF:10033-101E6

18-54 years, mixed

1031.3

PONS - Mouse RNA-seqⁱ

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	135.7

Mouse sample

Sample description

nTPM

Pons
nTPM: 135.7

Samples: 4

Max nTPM: 157.7
Min nTPM: 120.9

Sample A		131.1
Sample B		120.9
Sample C		157.7
Sample D		133.0

PONS - Rat RNA-seq

Max subtype nTPMⁱ Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.	339.6

Rat sample

Sample description

nTPM

Pons
nTPM: 339.6

Samples: 4

Max nTPM: 353.5
Min nTPM: 317.3

Sample A		317.3
Sample A		353.5
Sample A		337.6
Sample A		349.8