On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cells in granular layer:
High
Cells in molecular layer:
High
Purkinje cells:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.
Scroll down to view mRNA expression data in more detail.
HPA Brain:
186.0
nTPM
FANTOM5:
73.7
Scaled Tags Per Million
Macaque:
82.8
nTPM
Mouse:
34.3
nTPM
Rat:
50.8
nTPM
Pig:
39.5
nTPM
CEREBELLUM - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.
Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)
Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts
Antibody HPA001814
Purkinje cells
High
Cells in granular layer
High
Cells in molecular layer
High
CEREBELLUM - PROTEINTALKS DB MS
Median intensity
65994
Sample
Intensity
Cerebellum_01
68338
Cerebellum_02
90220
Cerebellum_03
44138
Cerebellum_04
65993
Cerebellum_05
75479
Cerebellum_06
59347
Cerebellum_07
52692
Cerebellum_08
65527
Cerebellum_09
63174
Cerebellum_10
78700
Cerebellum_11
78913
CEREBELLUM - HPA Brain Stereo-seq
CEREBELLUM - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
186.0
Sample id
Sample description
nTPM
Cerebellar cortex nTPM: 108.4
2101
Male, age 74, right hemisphere
177.0
1768
Female, age 72, unknown
141.2
2055
Female, age 91, right hemisphere
108.7
2003
Female, age 85, right hemisphere
108.5
1788
Male, age 55, unknown
108.3
2006
Male, age 61, right hemisphere
82.2
1774
Male, age 80, left hemisphere
74.8
1769
Male, age 76, right hemisphere
66.8
Cerebellar nuclei nTPM: 186.0
2783
Female, age 72, unknown
259.8
2882
Male, age 76, left hemisphere
190.9
1879
Male, age 55, unknown
190.4
1966
Female, age 91, left hemisphere
190.2
2177
Female, age 85, both hemispheres
189.3
2175
Male, age 61, right hemisphere
177.3
2005
Male, age 80, left hemisphere
169.7
2318
Male, age 74, left hemisphere
166.9
1871
Male, age 74, unknown
139.5
Cerebellar white matter nTPM: 144.0
2105
Male, age 74, right hemisphere
186.3
2773
Female, age 85, right hemisphere
154.9
1931
Female, age 91, left hemisphere
145.1
1837
Male, age 76, left hemisphere
134.0
1864
Male, age 80, left hemisphere
130.8
2174
Male, age 61, right hemisphere
113.2
Flocculonodular lobe nTPM: 111.1
2004
Male, age 61, right hemisphere
213.4
1792
Male, age 74, unknown
122.4
2176
Female, age 91, right hemisphere
105.9
1765
Male, age 55, unknown
102.1
1835
Female, age 85, right hemisphere
96.2
1771
Male, age 80, left hemisphere
73.0
1767
Male, age 76, left hemisphere
64.3
Vermis nTPM: 117.5
1928
Female, age 72, unknown
164.9
1751
Male, age 74, right hemisphere
164.1
1766
Male, age 55, unknown
130.1
2460
Male, age 61, both hemispheres
112.4
1825
Male, age 74, unknown
109.8
2834
Male, age 80, left hemisphere
107.7
1988
Female, age 85, left hemisphere
101.5
1778
Female, age 91, left hemisphere
100.4
1770
Male, age 76, left hemisphere
66.8
CEREBELLUM - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
82.8
Macaque sample
Sample description
nTPM
Cerebellum nTPM: 82.8
Samples: 3
Max nTPM: 89.7
Min nTPM: 78.6
Sample A
80.2
Sample B
78.6
Sample C
89.7
CEREBELLUM - Pig RNA-seqi
RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
39.5
Pig sample
Sample description
nTPM
Cerebellum nTPM: 39.5
Samples: 3
Max nTPM: 44.5
Min nTPM: 37.0
Sample B
Female
44.5
Sample C
Male
37.0
Sample D
Male
37.0
CEREBELLUM - Mouse RNA-seqi
RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
34.3
Mouse sample
Sample description
nTPM
Cerebellum nTPM: 34.3
Samples: 4
Max nTPM: 36.5
Min nTPM: 30.3
Sample A
35.5
Sample B
36.5
Sample C
35.0
Sample D
30.3
CEREBELLUM - Rat RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
50.8
Rat sample
Sample description
nTPM
Cerebellum nTPM: 50.8
Samples: 4
Max nTPM: 53.1
Min nTPM: 48.3
Sample A
52.0
Sample A
53.1
Sample A
48.3
Sample A
49.7
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The Human Protein Atlas project is funded
