On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units. Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set. If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Glial cells:
Low
Neuronal cells:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas HPA, Genotype-Tissue Expression GTEx portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets. The mRNA expression levels in pig brain are based on RNA-seq data generated by the Human Protein Atlas, and for mouse brain HPA data and in situ hybridization generated by the Allen brain atlas dataset are reported.
Scroll down to view mRNA expression data in more detail.
HPA Brain:
181.8
nTPM
FANTOM5:
181.8
Scaled Tags Per Million
Macaque:
97.0
nTPM
Mouse:
43.3
nTPM
Rat:
57.0
nTPM
Pig:
75.1
nTPM
HIPPOCAMPUS - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells. Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Ascending and descending describe two types of gradient, based on difference in staining intensity between enterocytes in crypts and apical enterocytes.
Ascending - the staining intensity is stronger in apical enterocytes (towards the lumen) compared to enterocytes in the crypts (gland based)
Descending - the staining is weaker in apical enterocytes compared to enterocytes in crypts
Antibody HPA001814
Glial cells
Low
Neuronal cells
High
HIPPOCAMPAL FORMATION - PROTEINTALKS DB MS
Median intensity
56377
Sample
Intensity
Hippocampal formation_01
47330
Hippocampal formation_02
48184
Hippocampal formation_03
26552
Hippocampal formation_04
74365
Hippocampal formation_05
64570
Hippocampal formation_06
99782
HIPPOCAMPAL FORMATION - HPA Brain Stereo-seq
HIPPOCAMPAL FORMATION - HPA Brain RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
181.8
Sample id
Sample description
nTPM
Dentate gyrus nTPM: 181.8
2010
Male, age 76, both hemispheres
253.4
2528
Male, age 74, both hemispheres
188.5
2530
Female, age 94, left hemisphere
180.6
1927
Female, age 91, both hemispheres
163.9
2246
Female, age 85, both hemispheres
160.0
2531
Female, age 67, both hemispheres
144.4
Entorhinal gyrus nTPM: 158.4
2686
Male, age 75, right hemisphere
186.4
2764
Male, age 80, right hemisphere
166.4
1938
Female, age 85, left hemisphere
166.0
2117
Female, age 91, right hemisphere
164.1
1787
Male, age 76, left hemisphere
151.3
2613
Female, age 94, left hemisphere
116.1
Hippocampus, CA1 nTPM: 167.4
2527
Male, age 74, both hemispheres
197.6
2082
Female, age 91, right hemisphere
169.5
2045
Male, age 76, both hemispheres
162.1
1873
Female, age 85, both hemispheres
160.7
2749
Male, age 80, left hemisphere
147.0
Hippocampus, CA2 nTPM: 176.8
2249
Male, age 74, both hemispheres
242.4
2437
Female, age 94, left hemisphere
175.6
1963
Male, age 80, left hemisphere
175.1
1940
Female, age 85, left hemisphere
170.7
2113
Female, age 91, right hemisphere
157.2
1892
Male, age 76, both hemispheres
139.6
Hippocampus, CA3 nTPM: 170.1
2436
Male, age 74, both hemispheres
271.4
1867
Male, age 76, both hemispheres
187.7
2137
Male, age 80, left hemisphere
160.5
1891
Female, age 85, both hemispheres
137.1
2861
Female, age 67, both hemispheres
136.2
2620
Female, age 94, left hemisphere
127.5
Parahippocampal cortex nTPM: 158.8
2018
Male, age 76, both hemispheres
205.5
2250
Female, age 67, right hemisphere
194.1
2532
Female, age 72, left hemisphere
167.4
2245
Female, age 91, both hemispheres
166.8
1933
Female, age 85, both hemispheres
159.0
1990
Female, age 91, right hemisphere
155.7
1850
Male, age 80, both hemispheres
146.1
2692
Male, age 74, both hemispheres
136.9
2622
Female, age 67, right hemisphere
133.7
2693
Female, age 94, both hemispheres
123.0
Perirhinal gyrus nTPM: 149.6
1847
Female, age 91, left hemisphere
180.7
1841
Female, age 85, right hemisphere
164.7
2521
Female, age 94, right hemisphere
155.5
1794
Male, age 80, right hemisphere
139.4
2848
Male, age 76, right hemisphere
107.8
Subiculum nTPM: 161.9
2042
Male, age 76, both hemispheres
173.4
1977
Female, age 85, both hemispheres
166.6
1901
Male, age 80, both hemispheres
160.8
2438
Female, age 94, left hemisphere
159.7
2619
Male, age 74, both hemispheres
158.7
2729
Female, age 91, right hemisphere
152.1
HIPPOCAMPAL FORMATION - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
Max subtype Scaled Tags Per Millioni
Max subtype Scaled Tags Per Million is the value for the subtype with the largest average Scaled Tags Per Million across the subtype samples.
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
97.0
Macaque sample
Sample description
nTPM
Subiculum nTPM: 80.7
Samples: 1
Max nTPM: 80.7
Min nTPM: 80.7
Sample A
80.7
Entorhinal cortex nTPM: 97.0
Samples: 2
Max nTPM: 117.4
Min nTPM: 76.6
Sample A
117.4
Sample B
76.6
Hippocampal formation nTPM: 96.1
Samples: 4
Max nTPM: 115.3
Min nTPM: 81.2
Sample A
90.6
Sample B
81.2
Sample C
97.4
Sample D
115.3
HIPPOCAMPAL FORMATION - Pig RNA-seqi
RNA-seq data obtained from pig brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
75.1
Pig sample
Sample description
nTPM
Subiculum nTPM: 75.2
Samples: 4
Max nTPM: 102.0
Min nTPM: 60.5
Sample A
Female
102.0
Sample B
Female
66.5
Sample C
Male
71.6
Sample D
Male
60.5
Dorsal hippocampus nTPM: 68.0
Samples: 4
Max nTPM: 79.9
Min nTPM: 54.2
Sample A
Female
79.9
Sample B
Female
69.0
Sample C
Male
68.8
Sample D
Male
54.2
Entorhinal cortex nTPM: 67.8
Samples: 4
Max nTPM: 80.1
Min nTPM: 55.8
Sample A
Female
65.4
Sample B
Female
80.1
Sample C
Male
69.7
Sample D
Male
55.8
Ventral hippocampus nTPM: 69.9
Samples: 4
Max nTPM: 84.7
Min nTPM: 57.8
Sample A
Female
75.8
Sample B
Female
57.8
Sample C
Male
84.7
Sample D
Male
61.4
HIPPOCAMPAL FORMATION - Mouse RNA-seqi
RNA-seq data obtained from mouse brain is reported as nTPM. Normal distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
43.3
Mouse sample
Sample description
nTPM
Entorhinal cortex nTPM: 43.3
Samples: 4
Max nTPM: 49.0
Min nTPM: 38.5
Sample A
42.1
Sample B
43.5
Sample C
38.5
Sample D
49.0
Hippocampal formation nTPM: 34.2
Samples: 4
Max nTPM: 38.8
Min nTPM: 31.1
Sample A
31.7
Sample B
31.1
Sample C
35.3
Sample D
38.8
HIPPOCAMPAL FORMATION - Rat RNA-seq
Max subtype nTPMi
Max subtype nTPM is the value for the subtype with the largest average nTPM across the subtype samples.
57.0
Rat sample
Sample description
nTPM
Entorhinal cortex nTPM: 55.0
Samples: 4
Max nTPM: 59.6
Min nTPM: 51.2
Sample A
59.6
Sample A
56.8
Sample A
51.2
Sample B
52.3
Ventral hippocampus nTPM: 57.0
Samples: 4
Max nTPM: 60.7
Min nTPM: 51.5
Sample A
58.5
Sample A
51.5
Sample A
57.4
Sample A
60.7
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