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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Not detected
Hepatocytes:
High
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
145.5
nTPM
HPA:
145.5
nTPM
GTEx:
69.9
nTPM
FANTOM5:
167.0
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA018997
Cholangiocytes
Not detected
Hepatocytes
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
145.5
Female, age 60
Liver sample 21 nTPM: 104.9
Male, age 54
Liver sample 23 nTPM: 74.5
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 150.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 170.4
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 152.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 139.8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 147.3
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 146.8
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 141.4
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 227.4
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
69.9
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 69.9
Samples: 226
Max nTPM: 139.9
Min nTPM: 13.8
Std nTPM: 26.3
Median nTPM: 71.7
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
139.9
GTEX-17HHE-0126-SM-79398
50-59 years, male
132.5
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
128.4
GTEX-14JG1-1626-SM-664NH
40-49 years, male
127.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
127.3
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
124.2
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
119.6
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
119.0
GTEX-YECK-1926-SM-4W21H
60-69 years, male
118.9
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
116.2
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
115.8
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
113.6
GTEX-18A7A-1526-SM-72D69
50-59 years, female
113.0
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
113.0
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
111.3
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
109.8
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
109.2
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
108.0
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
108.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
104.4
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
104.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
103.4
GTEX-R53T-0326-SM-48FEC
50-59 years, female
103.1
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
102.6
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
102.6
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
98.7
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
98.4
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
97.7
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
97.7
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
97.5
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
97.5
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
96.5
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
96.2
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
96.1
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
95.5
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
95.3
GTEX-13112-1426-SM-5EGH8
50-59 years, male
94.6
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
94.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
94.4
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
94.1
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
94.0
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
93.1
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
92.9
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
92.5
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
92.3
GTEX-14E7W-1526-SM-6871X
70-79 years, male
92.2
GTEX-1399T-0826-SM-5IFES
60-69 years, male
90.9
GTEX-144GL-1426-SM-79OMA
50-59 years, male
90.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
90.5
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
90.4
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
90.1
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
89.0
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
88.3
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
88.1
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
87.9
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
87.9
GTEX-18465-1626-SM-7LG6N
50-59 years, male
87.5
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
87.4
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
86.6
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
86.3
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
86.1
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
86.1
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
85.8
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
85.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
84.7
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
84.6
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
84.5
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
84.4
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
84.4
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
84.0
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
83.7
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
83.7
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
83.6
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
82.8
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
82.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
82.6
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
82.0
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
81.8
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
81.7
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
80.9
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
80.8
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
80.7
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
80.6
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
80.5
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
80.5
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
79.5
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
79.3
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
78.4
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
77.9
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
77.9
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
77.2
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
77.2
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
76.9
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
76.6
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
76.6
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
76.5
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
76.1
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
75.8
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
75.7
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
75.6
GTEX-P78B-1326-SM-3P611
40-49 years, female
75.6
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
75.2
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
74.7
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
73.7
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
73.6
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
73.4
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
73.3
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
73.3
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
73.2
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
72.7
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
72.2
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
72.0
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
71.9
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
71.6
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
70.5
GTEX-RU72-1426-SM-46MUF
50-59 years, female
70.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
69.6
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
69.6
GTEX-1B933-1226-SM-731DW
50-59 years, female
69.3
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
69.1
GTEX-18A66-2026-SM-7189C
60-69 years, male
69.1
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
68.8
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
68.6
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
68.5
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
68.5
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
68.3
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
67.9
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
67.6
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
67.6
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
67.5
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
67.1
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
66.7
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
66.6
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
66.6
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
65.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
64.7
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
64.6
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
64.1
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
64.0
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
64.0
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
63.9
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
63.5
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
61.1
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
61.1
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
61.0
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
60.7
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
60.2
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
60.0
GTEX-14PHX-0526-SM-664NW
50-59 years, male
59.9
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
59.6
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
59.1
GTEX-13113-1326-SM-5GCOI
60-69 years, female
58.6
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
58.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
57.1
GTEX-17F96-1226-SM-79OK2
70-79 years, male
57.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
56.5
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
56.5
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
56.3
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
56.2
GTEX-S32W-1926-SM-4AD63
50-59 years, female
55.8
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
54.9
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
54.8
GTEX-S33H-1626-SM-4AD68
30-39 years, male
54.3
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
54.2
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
52.3
GTEX-X261-1726-SM-4PQYT
50-59 years, male
51.7
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
51.6
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
51.0
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
51.0
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
50.3
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
49.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
48.3
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
48.1
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
48.0
GTEX-1B932-1426-SM-793AN
40-49 years, female
47.6
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
46.6
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
46.3
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
46.1
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
45.7
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
45.5
GTEX-REY6-1226-SM-48FDR
60-69 years, male
45.3
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
45.2
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
44.4
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
44.1
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
43.2
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
42.2
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
42.1
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
41.9
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
41.8
GTEX-14XAO-0226-SM-68728
60-69 years, female
41.3
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
39.6
GTEX-11GSP-0626-SM-5986T
60-69 years, female
38.2
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
38.2
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
38.0
GTEX-O5YV-0726-SM-EV798
60-69 years, female
37.8
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
37.5
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
37.1
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
37.1
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
36.2
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
35.8
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
35.1
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
34.4
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
34.3
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
33.7
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
31.8
GTEX-QEL4-1226-SM-447A4
50-59 years, male
30.9
GTEX-Q734-0326-SM-48U15
40-49 years, female
30.0
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
28.1
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
27.9
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
27.3
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
27.2
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
27.1
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
26.1
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
25.9
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
25.1
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
25.0
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
24.1
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
24.0
GTEX-14PJO-1726-SM-68719
60-69 years, male
23.9
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
22.9
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
22.6
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
21.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
20.3
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
19.7
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
16.0
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
13.8
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
