CALCR

GENERAL INFORMATION

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Gene name

CALCR

Gene description

Calcitonin receptor

Protein class

Predicted membrane proteins
Predicted secreted proteins

Predicted localization

Membrane,Secreted

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (kidney)
GTEx:Tissue enhanced (kidney)

Protein evidence

Evidence at transcript level

Protein localization

RNA data suggests low expression in kidney and testis. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA028962
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (kidney)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (kidney)

Organ

Expression



GENE INFORMATION

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Gene name

CALCR (HGNC Symbol)

Synonyms

CTR

Description

Calcitonin receptor (HGNC Symbol)

Entrez gene summary

This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]

Chromosome

7

Cytoband

q21.3

Chromosome location (bp)

93424487 - 93574730

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000004948 (version 78.38)

Entrez gene

799

UniProt

neXtProt

Antibodypedia

CALCR antibodies


PROTEIN BROWSER

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ENST00000359558
 
ENST00000360249
 
ENST00000394441
 
ENST00000421592
 
ENST00000426151
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CALCR-001 ENSP00000399552
ENST00000421592
X2J7C8
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Show » Show » 490 57.3 Yes 7
CALCR-002 ENSP00000377959
ENST00000394441
A4D1G6
Show all »
Show » Show » 474 55.3 Yes 7
CALCR-005 ENSP00000389295
ENST00000426151
A4D1G6
Show all »
Show » Show » 474 55.3 Yes 7
CALCR-201 ENSP00000352561
ENST00000359558
X2J7C8
Show all »
Show » Show » 508 59.4 Yes 7
CALCR-202 ENSP00000353385
ENST00000360249
D8MIV0
Show all »
Show » Show » 162 19.1 Yes 0