AP2B1

GENERAL INFORMATION

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Gene name

AP2B1

Gene description

Adaptor-related protein complex 2, beta 1 subunit

Protein class

Cancer-related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

13
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression at variable levels in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
CAB017631
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

AP2B1 (HGNC Symbol)

Synonyms

ADTB2, CLAPB1

Description

Adaptor-related protein complex 2, beta 1 subunit (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is one of two large chain components of the assembly protein complex 2, which serves to link clathrin to receptors in coated vesicles. The encoded protein is found on the cytoplasmic face of coated vesicles in the plasma membrane. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

17

Cytoband

q12

Chromosome location (bp)

35578046 - 35726409

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000006125 (version 78.38)

Entrez gene

163

UniProt

P63010 (UniProt - Evidence at protein level)

neXtProt

NX_P63010

Antibodypedia

AP2B1 antibodies


PROTEIN BROWSER

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ENST00000587805
 
ENST00000589774
 
ENST00000590432
 
ENST00000593014
 
ENST00000610402
 
ENST00000612035
 
ENST00000612116
 
ENST00000614600
 
ENST00000616681
 
ENST00000616784
 
ENST00000618940
 
ENST00000621668
 
ENST00000621914
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AP2B1-001 ENSP00000478471
ENST00000616784
K7ERB2
Show all »
Show » Show » 663 74.1 No 0
AP2B1-004 ENSP00000481704
ENST00000621668
K7EJX1
Show all »
Show » Show » 639 70.9 No 0
AP2B1-005 ENSP00000482825
ENST00000612035
K7ERB2
Show all »
Show » Show » 677 75.3 No 0
AP2B1-006 ENSP00000478115
ENST00000612116
K7ERB2
Show all »
Show » Show » 677 75.3 No 0
AP2B1-007 ENSP00000479691
ENST00000614600
K7ERB2
Show all »
Show » Show » 677 75.3 No 0
AP2B1-009 ENSP00000468183
ENST00000589774
K7ERB2
Show all »
Show » Show » 151 17.2 No 0
AP2B1-010 ENSP00000465357
ENST00000590432
K7EJX1
Show all »
Show » Show » 80 9.2 No 0
AP2B1-011 ENSP00000466812
ENST00000593014
K7EN71
Show all »
Show » Show » 132 15.1 No 0
AP2B1-018 ENSP00000466580
ENST00000587805
K7EMN7
Show all »
Show » Show » 181 20.4 No 0
AP2B1-019 ENSP00000482315
ENST00000621914
P63010
Show all »
Show » Show » 937 104.6 No 0
AP2B1-021 ENSP00000484708
ENST00000616681
Q96EL6
Show all »
Show » Show » 913 101.3 No 0
AP2B1-022 ENSP00000483185
ENST00000610402
P63010
Show all »
Show » Show » 951 105.7 No 0
AP2B1-201 ENSP00000482835
ENST00000618940
P63010
Show all »
Show » Show » 951 105.7 No 0