We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
LGALS14
SECTIONS
  • TISSUE
  • BRAIN
  • SINGLE CELL TYPE
  • TISSUE CELL TYPE
  • PATHOLOGY
  • DISEASE
  • IMMUNE CELL
  • BLOOD PROTEIN
  • SUBCELLULAR
  • CELL LINE
  • STRUCTURE
  • METABOLIC
ABOUT
  • INTRODUCTION
  • HISTORY
  • ORGANIZATION
  • PUBLICATIONS
  • ANTIBODY SUBMISSION
  • ANTIBODY AVAILABILITY
  • ACKNOWLEDGMENTS
  • CONTACT
NEWS
  • NEWS ARTICLES
  • PRESS ROOM
LEARN
  • DICTIONARY
  • PROTEIN CLASSES
  • PROTEIN EVIDENCE
  • METHODS
  • EDUCATIONAL VIDEOS
DATA
  • DOWNLOADABLE DATA
  • PUBLICATION DATA
  • RELEASE HISTORY
  • SARS-COV-2
HELP
  • ANTIBODY VALIDATION
  • ASSAYS & ANNOTATION
  • DISCLAIMER
  • HELP & FAQ
  • PRIVACY STATEMENT
  • LICENCE & CITATION
Fields »
Search result

Field
Term
Gene name
Class
Subclass
Class
Keyword
Chromosome
External id
Tissue
Cell type
Expression
Patient ID
Tissue
Category
Cluster
Reliability
Brain region
Category
Brain region
Category
Brain region
Category
Reliability
Cell type
Category
Cluster
Tissue
Cell type
Enrichment
Cancer
Prognosis
Cancer
Category
Cell type
Category
Cell lineage
Category
Cluster
Annotation
Disease
Location
Searches
Location
Cell line
Type
Phase
Reliability
Cancer type
Category
Cluster
Pathway
Category
Score
Score
Score
Validation
Validation
Validation
Validation
Antibodies
Protein structure
In atlas
Column


  • SUMMARY

  • TISSUE

  • BRAIN

  • SINGLE CELL

  • TISSUE CELL

  • PATHOLOGY

  • DISEASE

  • IMMUNE

  • BLOOD

  • SUBCELL

  • CELL LINE

  • STRUCTURE

  • METABOLIC

  • LGALS14
CELL LINE
BILE DUCT CANCER BLADDER CANCER BONE CANCER BRAIN CANCER BREAST CANCER CERVICAL CANCER COLORECTAL CANCER ESOPHAGEAL CANCER GALLBLADDER CANCER GASTRIC CANCER
HEAD AND NECK CANCER KIDNEY CANCER LEUKEMIA LIVER CANCER LUNG CANCER LYMPHOMA MYELOMA NEUROBLASTOMA NON-CANCEROUS OVARIAN CANCER
PANCREATIC CANCER PROSTATE CANCER RHABDOID SARCOMA SKIN CANCER TESTIS CANCER THYROID CANCER UNCATEGORIZED UTERINE CANCER
Human cell lines
GENERAL INFORMATIONi

General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.

Gene namei

Official gene symbol, which is typically a short form of the gene name, according to HGNC.

LGALS14
Gene descriptioni

Full gene name according to HGNC.

Galectin 14
Predicted locationi

All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions.

  • Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached.

  • Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s).

The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location.

Read more
Intracellular
Number of transcriptsi

Number of protein-coding transcripts from the gene as defined by Ensembl.

3
HUMAN PROTEIN ATLAS INFORMATIONi

Summary of RNA expression based on cell line data from the DepMap portal and cell line data generated within the Human Protein Atlas project.

Cell line expression clusteri

The RNA data was used to cluster genes according to their expression across cell lines. Clusters contain genes that have similar expression patterns, and each cluster has been manually annotated to describe common features in terms of function and specificity.

Read more
Non-specific - Cilium assembly (mainly)
Cell line specificityi

RNA specificity category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.

Read more
Cancer enhanced (Gastric cancer, Uterine cancer)
Tau specificity scorei

Tau specificity score is a numerical indicator of the specificity of the gene expression across cells or tissues. The value ranges from 0 and 1, where 0 indicates identical expression across all cells/tissue types, while 1 indicates expression in a single cell/tissue type.

Read more
0.72
Cell line distributioni

RNA distribution category based on RNA sequencing data from cancer cell lines in the Human Protein Atlas grouped according to type of cancer. Genes are classified into five different categories (detected in all, detected in many, detected in some, detected in single and not detected) according to their pattern of detected RNA expression across the panel of cell lines.

Read more
Detected in some
Protein evidencei

Evidence score for genes based on UniProt protein existence (UniProt evidence); a Human Protein Atlas antibody- or RNA based score (HPA evidence); and evidence based on PeptideAtlas (MS evidence). The avaliable scores are evidence at protein level, evidence at transcript level, no evidence, or not avaliable.

Read more
Evidence at protein level
CELL LINESi

RNA expression data as normalized transcript per million (nTPM) values of cancer cell lines.The analyzed cell lines are grouped according to cancer type. Detailed information about the groups is revealed by hovering over the corresponding bar in the chart. More information and cell line data can be found in the Cell line section.

Read more
Cell line categories
Alphabetical
Expression
RNA specificity:Cancer enhanced (Gastric cancer, Uterine cancer)

EXPRESSION CLUSTERING & CORRELATIONi

The RNA data was used to cluster genes according to their expression across samples. The resulting clusters have been manually annotated to describe common features in terms of function and specificity. The annotation of the cluster is displayed together with a confidence score of the gene's assignment to the cluster. The confidence is calculated as the fraction of times the gene was assigned to this cluster in repeated calculations and is reported between 0 to 1, where 1 is the highest possible confidence. The clustering results are shown in a UMAP, where the cluster this gene was assigned to is highlighted as a colored area in which most of the cluster genes reside. A table shows the 15 most similar genes in terms of expression profile.

Read more
LGALS14 is part of cluster 41 Non-specific - Cilium assembly with confidencei

Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and therefore reflects how strongly associated it is to the cluster. A confidence of 1 indicates that the gene was assigned to this cluster in all repeated clusterings.

Read more
1
688 genes in cluster
Go to interactive expression cluster page
15 nearest neighbours based on cell line RNA expression
Neighbouri

Gene name according to HGNC.

Descriptioni

Gene description according to HGNC.

Correlationi

Correlation between the selected gene and neighboring gene. Correlation is calculated as Spearman correlation in PCA space based on the RNA-seq expression data.

Read more
Clusteri

ID of the expression cluster of the neighboring gene.

Read more
UGT2A2 UDP glucuronosyltransferase family 2 member A2 0.7377 41
UGT2A1 UDP glucuronosyltransferase family 2 member A1 complex locus 0.7288 41
KLHL1 Kelch like family member 1 0.7191 41
WEE2 WEE2 oocyte meiosis inhibiting kinase 0.7052 41
SPANXN2 SPANX family member N2 0.6916 41
CNMD Chondromodulin 0.6547 41
RETNLB Resistin like beta 0.6496 41
C20orf85 Chromosome 20 open reading frame 85 0.6485 41
C22orf42 Chromosome 22 open reading frame 42 0.6468 41
TMEM207 Transmembrane protein 207 0.6454 41
SSU72P3 SSU72 pseudogene 3 0.6372 10
MS4A15 Membrane spanning 4-domains A15 0.6350 41
SSU72P7 SSU72 pseudogene 7 0.6251 10
DLX5 Distal-less homeobox 5 0.5998 41
TAFA1 TAFA chemokine like family member 1 0.5716 41

CELL LINE DATA
Alphabetical
Expression
Bile duct cancer (n=7)
Alphabetical
Expression
Bladder cancer (n=26)
Alphabetical
Expression
Bone cancer (n=19)
Alphabetical
Expression
Brain cancer (n=65)
Alphabetical
Expression
Breast cancer (n=50)
Alphabetical
Expression
Cervical cancer (n=3)
Alphabetical
Expression
Colorectal cancer (n=57)
Alphabetical
Expression
Esophageal cancer (n=27)
Alphabetical
Expression
Gallbladder cancer (n=1)
Alphabetical
Expression
Gastric cancer (n=38)
Alphabetical
Expression
Head and Neck cancer (n=33)
Alphabetical
Expression
Kidney cancer (n=31)
Alphabetical
Expression
Leukemia (n=88)
Alphabetical
Expression
Liver cancer (n=24)
Alphabetical
Expression
Lung cancer (n=196)
Alphabetical
Expression
Lymphoma (n=57)
Alphabetical
Expression
Myeloma (n=34)
Alphabetical
Expression
Neuroblastoma (n=17)
Alphabetical
Expression
Non-cancerous (n=60)
Alphabetical
Expression
Ovarian cancer (n=46)
Alphabetical
Expression
Pancreatic cancer (n=41)
Alphabetical
Expression
Prostate cancer (n=7)
Alphabetical
Expression
Rhabdoid (n=14)
Alphabetical
Expression
Sarcoma (n=14)
Alphabetical
Expression
Skin cancer (n=50)
Alphabetical
Expression
Testis cancer (n=1)
Alphabetical
Expression
Thyroid cancer (n=11)
Alphabetical
Expression
Uncategorized (n=10)
Alphabetical
Expression
Uterine cancer (n=28)

Contact

  • NEWS ARTICLES
  • PRESS ROOM
  • contact@proteinatlas.org

The Project

  • INTRODUCTION
  • ORGANIZATION
  • PUBLICATIONS

The Human Protein Atlas

  • DOWNLOADABLE DATA
  • LICENCE & CITATION
  • HELP & FAQ
The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg Foundation.