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On the top, protein expression in current human tissue, based on all annotated cell types, is reported with the units not detected (n), low (l), medium (m) and high (h). Underneath, protein expression in each annotated cell type are reported using the same units.
Protein expression data is based on knowledge-based annotation. For genes where more than one antibody has been used, a collective score is set.
If knowledge-based annotation could not be performed for a gene, no data is displayed here. View antibody staining data further down this page.
h
m
l
n
Cholangiocytes:
Low
Hepatocytes:
Medium
RNA expressioni
A summary of mRNA expression data available for current tissue based on several datasets. The mRNA expression levels in human tissues are based on RNA-seq data generated by the Human Protein Atlas (HPA), Genotype-Tissue Expression (GTEx) portal and CAGE data generated by the FANTOM5 consortium. Consensus normalized expression levels for human tissues was created by combining the data from HPA and GTEx datasets.
The mRNA expression levels in pig are based on RNA-seq data generated by the Human Protein Atlas (HPA), and for mouse, HPA data and in situ hybridization generated by the Allen brain atlas are reported.
Scroll down to view mRNA expression data in more detail.
Consensus:
10.3
nTPM
HPA:
8.7
nTPM
GTEx:
10.3
nTPM
FANTOM5:
12.6
Scaled Tags Per Million
LIVER - Antibody stainingi
Antibody staining in the annotated cell types in the current human tissue is reported as not detected, low, medium, or high, based on conventional immunohistochemistry profiling in selected tissues. This score is based on the combination of the staining intensity and fraction of stained cells.
Each image is clickable and will lead to virtual microscopy that enables deeper exploration of all samples and also displays staining intensity scores, fraction scores and subcellular localization as well as patient and tissue information for each sample.
Antibody HPA032005
Antibody HPA032006
Cholangiocytes
Not detected
Medium
Hepatocytes
Not detected
High
LIVER - HPA RNA-seqi
The RNA-seq details section shows detailed information about the individual samples used for the transcript profiling and results of the RNA-seq analysis.
Information about each individual sample is listed below, including gender, age, a tissue section image and estimated fractions of cell types. nTPM (normalized transcripts per million) values give a quantification of the gene abundance which is comparable between different genes and samples.
Average nTPM
8.7
Female, age 60
Liver sample 21 nTPM: 6.8
Male, age 54
Liver sample 23 nTPM: 7.7
Cell types%
Hepatocytes:
80
Fibroblasts:
15
Other cell types:
5
Male, age 74
Liver sample 24 nTPM: 7.1
Cell types%
Hepatocytes:
85
Fibroblasts:
5
Other cell types:
10
Female, age 62
Liver sample 350 nTPM: 8
Cell types%
Hepatocytes:
70
Fibroblasts:
10
Other cell types:
20
Male, age 78
Liver sample 351 nTPM: 10.5
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Male, age 53
Liver sample 352 nTPM: 8
Cell types%
Hepatocytes:
80
Fibroblasts:
5
Other cell types:
15
Male, age 77
Liver sample 353 nTPM: 10.9
Cell types%
Hepatocytes:
75
Fibroblasts:
5
Other cell types:
20
Female, age 72
Liver sample 359 nTPM: 6.5
Cell types%
Hepatocytes:
50
Fibroblasts:
10
Other cell types:
40
Male, age 70
Liver sample 367 nTPM: 7.2
Cell types%
Hepatocytes:
65
Fibroblasts:
10
Other cell types:
25
Female, age 23
Liver sample 396 nTPM: 13.9
Cell types%
Hepatocytes:
70
Fibroblasts:
5
Other cell types:
25
LIVER - GTEx RNA-seqi
RNA-Seq data generated by the Genotype-Tissue Expression (GTEx) project from human tissues is reported as mean nTPM. More information can be found on the GTEx portal.
Distribution across the dataset is visualized with box plots, shown as median and 25th and 75th percentiles. Points are displayed as outliers if they are above or below 1.5 times the interquartile range. nTPM values of the individual samples are presented next to the box plot.
Average nTPM
10.3
GTEx sample id
Sample description
nTPM
Liver Average nTPM: 10.3
Samples: 226
Max nTPM: 22.5
Min nTPM: 5.3
Std nTPM: 2.7
Median nTPM: 9.9
GTEX-11TT1-1726-SM-5EQLJ
20-29 years, male
22.5
GTEX-1GN73-1126-SM-9OSW5
60-69 years, male
20.4
GTEX-1A32A-0826-SM-72D5C
50-59 years, female
20.2
GTEX-1GN1U-0926-SM-9WPPY
50-59 years, female
17.3
GTEX-1AMFI-0826-SM-731DV
50-59 years, female
16.6
GTEX-12WSG-0626-SM-5FQTQ
50-59 years, female
16.5
GTEX-ZVT4-0626-SM-5E45T
50-59 years, female
16.5
GTEX-13N11-0926-SM-5IJG2
50-59 years, female
16.4
GTEX-13O3O-1826-SM-5IFGW
60-69 years, female
16.1
GTEX-145MO-2326-SM-5NQ9K
60-69 years, male
16.1
GTEX-RWSA-1426-SM-47JXA
40-49 years, male
16.1
GTEX-13SLX-1226-SM-5S2Q6
50-59 years, female
15.9
GTEX-15SZO-1226-SM-6LPIP
50-59 years, male
15.5
GTEX-QEG4-1826-SM-CKZN9
30-39 years, male
15.5
GTEX-132AR-0426-SM-5IFH8
50-59 years, female
15.3
GTEX-13O1R-2026-SM-5KM3N
60-69 years, male
15.2
GTEX-13113-1326-SM-5GCOI
60-69 years, female
15.1
GTEX-14C38-1526-SM-5RQJ7
50-59 years, male
15.1
GTEX-1A8FM-1226-SM-7IGMD
50-59 years, female
14.9
GTEX-1GN2E-0926-SM-9WPOH
60-69 years, male
14.8
GTEX-13QJC-0726-SM-5RQJK
60-69 years, female
14.7
GTEX-1JMLX-1326-SM-CXZJO
50-59 years, male
14.6
GTEX-X4EO-1126-SM-4QARQ
60-69 years, female
14.5
GTEX-13PVQ-1526-SM-5IFEQ
50-59 years, male
14.0
GTEX-1B996-1426-SM-7EPIA
60-69 years, male
13.9
GTEX-WY7C-0726-SM-4ONCB
50-59 years, male
13.8
GTEX-O5YT-0826-SM-3TW8N
20-29 years, male
13.7
GTEX-1IKJJ-1526-SM-C1YSC
60-69 years, male
13.5
GTEX-1NV8Z-1626-SM-DPRYT
60-69 years, male
13.5
GTEX-ZF29-2026-SM-DNZYW
60-69 years, female
13.4
GTEX-1GF9W-0826-SM-7MKHI
60-69 years, male
13.3
GTEX-ZTPG-1426-SM-51MT3
20-29 years, female
13.3
GTEX-11TUW-1726-SM-5BC5C
60-69 years, male
13.2
GTEX-S4Z8-0526-SM-4AD4T
60-69 years, male
13.2
GTEX-1AX9I-1626-SM-72D5D
60-69 years, male
13.1
GTEX-18465-1626-SM-7LG6N
50-59 years, male
12.9
GTEX-1QPFJ-1126-SM-E9U5V
30-39 years, female
12.9
GTEX-1QP6S-1326-SM-DPRZ8
40-49 years, male
12.7
GTEX-1212Z-0226-SM-59HLF
60-69 years, male
12.5
GTEX-11ZUS-2526-SM-59872
30-39 years, male
12.4
GTEX-ZZPU-0426-SM-5GZYH
50-59 years, female
12.4
GTEX-1269C-0626-SM-5FQSS
60-69 years, female
12.3
GTEX-QDVN-0826-SM-48TZ2
50-59 years, male
12.3
GTEX-1LH75-0926-SM-EAZ5C
50-59 years, female
12.3
GTEX-1497J-0726-SM-5Q5D1
60-69 years, male
12.1
GTEX-YEC4-0826-SM-5P9FV
40-49 years, male
12.1
GTEX-17HHE-0126-SM-79398
50-59 years, male
12.0
GTEX-RM2N-1926-SM-48FCU
50-59 years, male
11.9
GTEX-1LGRB-0626-SM-CNNQH
50-59 years, female
11.9
GTEX-1S82Y-1026-SM-EV7BJ
40-49 years, male
11.9
GTEX-14BIL-1326-SM-79OMR
50-59 years, male
11.8
GTEX-1CB4J-0726-SM-7IGN8
60-69 years, male
11.8
GTEX-REY6-1226-SM-48FDR
60-69 years, male
11.8
GTEX-13FTW-1126-SM-5J2NV
40-49 years, male
11.7
GTEX-17HII-1026-SM-7IGLY
50-59 years, male
11.7
GTEX-13FTZ-0726-SM-5IFFY
60-69 years, male
11.5
GTEX-1C6VQ-1626-SM-79OO1
50-59 years, male
11.5
GTEX-131XE-0326-SM-5LZVO
50-59 years, male
11.4
GTEX-RTLS-1326-SM-46MUN
60-69 years, female
11.4
GTEX-1EN7A-2026-SM-7MGY4
40-49 years, male
11.4
GTEX-14AS3-0126-SM-5Q5F4
40-49 years, female
11.3
GTEX-YB5E-0326-SM-5IFHU
40-49 years, male
11.3
GTEX-1BAJH-1526-SM-7RHGI
70-79 years, male
11.3
GTEX-13NYB-1026-SM-5IFH3
40-49 years, male
11.2
GTEX-14XAO-0226-SM-68728
60-69 years, female
11.2
GTEX-Z9EW-0426-SM-5CVM9
40-49 years, male
11.2
GTEX-ZYY3-0626-SM-5NQ6W
60-69 years, female
11.2
GTEX-OIZF-0826-SM-3MJGO
60-69 years, male
11.2
GTEX-U3ZN-0226-SM-3DB8D
30-39 years, female
11.1
GTEX-14753-1626-SM-5NQ9L
60-69 years, male
11.0
GTEX-15ER7-1826-SM-6LLI7
20-29 years, female
11.0
GTEX-1GF9V-1226-SM-7MKGY
60-69 years, male
11.0
GTEX-X4XY-1626-SM-46MVN
60-69 years, male
11.0
GTEX-YFC4-1526-SM-5IFJS
40-49 years, female
11.0
GTEX-11GSP-0626-SM-5986T
60-69 years, female
10.9
GTEX-1399R-1226-SM-5P9GF
30-39 years, male
10.9
GTEX-S32W-1926-SM-4AD63
50-59 years, female
10.9
GTEX-U8XE-1526-SM-4E3HT
30-39 years, male
10.9
GTEX-Y5LM-0426-SM-4VBRO
40-49 years, female
10.9
GTEX-Y5V5-0926-SM-4VBPZ
60-69 years, female
10.9
GTEX-1HT8W-0826-SM-C1YRJ
30-39 years, male
10.9
GTEX-11ZVC-0726-SM-5FQT9
50-59 years, female
10.8
GTEX-145MF-0826-SM-5QGQA
50-59 years, male
10.8
GTEX-1KAFJ-0726-SM-CXZKF
50-59 years, male
10.8
GTEX-14A5I-1726-SM-5QGQ5
50-59 years, female
10.7
GTEX-OOBJ-0826-SM-3NB2K
60-69 years, male
10.6
GTEX-WQUQ-1926-SM-4OOSA
60-69 years, male
10.6
GTEX-ZEX8-0826-SM-4WKHK
50-59 years, male
10.6
GTEX-1EH9U-1126-SM-7IGLU
60-69 years, male
10.5
GTEX-13PVR-0126-SM-5S2PY
60-69 years, female
10.4
GTEX-XXEK-1126-SM-4BRUX
50-59 years, male
10.4
GTEX-13112-1426-SM-5EGH8
50-59 years, male
10.3
GTEX-SJXC-1226-SM-4DM78
60-69 years, male
10.3
GTEX-X4EP-1026-SM-4QAS5
60-69 years, female
10.3
GTEX-13OW6-2626-SM-5IFF2
50-59 years, male
10.2
GTEX-1A8G7-1126-SM-731ED
60-69 years, male
10.2
GTEX-ZPU1-0826-SM-57WG2
40-49 years, male
10.2
GTEX-11EQ9-0526-SM-5A5JZ
30-39 years, male
10.1
GTEX-QESD-2026-SM-447BI
20-29 years, male
10.1
GTEX-X3Y1-2726-SM-4PQZH
40-49 years, male
10.1
GTEX-1CB4F-1726-SM-7MGXH
60-69 years, male
10.1
GTEX-1GZ4I-1526-SM-9OSW9
50-59 years, male
10.1
GTEX-1I1HK-1126-SM-AHZ2L
60-69 years, male
10.1
GTEX-1QCLZ-1226-SM-EAZ49
60-69 years, female
10.1
GTEX-146FH-1526-SM-5NQBU
50-59 years, female
10.0
GTEX-15RJE-1126-SM-6LPI5
40-49 years, male
10.0
GTEX-17F96-1226-SM-79OK2
70-79 years, male
10.0
GTEX-1B8L1-0726-SM-7P8RT
60-69 years, male
10.0
GTEX-O5YV-0726-SM-EV798
60-69 years, female
10.0
GTEX-11NV4-1326-SM-5HL6V
60-69 years, male
9.9
GTEX-147F4-1426-SM-5LUA8
50-59 years, male
9.9
GTEX-18A7A-1526-SM-72D69
50-59 years, female
9.9
GTEX-18D9B-1526-SM-7KFRK
60-69 years, male
9.9
GTEX-R53T-0326-SM-48FEC
50-59 years, female
9.9
GTEX-1IKK5-0326-SM-C1YPY
60-69 years, male
9.9
GTEX-Q2AG-1126-SM-48U1P
40-49 years, female
9.8
GTEX-1ICLY-1526-SM-C1YS4
50-59 years, male
9.8
GTEX-15RJ7-2026-SM-6LPJ4
40-49 years, male
9.7
GTEX-1EKGG-1226-SM-7IGNO
60-69 years, male
9.7
GTEX-RN64-1826-SM-48FDV
50-59 years, male
9.7
GTEX-1KWVE-0326-SM-EV7AF
30-39 years, male
9.7
GTEX-1R9JW-0826-SM-DPRZJ
30-39 years, female
9.7
GTEX-147JS-1126-SM-5RQIW
60-69 years, male
9.6
GTEX-14E1K-0326-SM-5S2PE
50-59 years, male
9.6
GTEX-18A6Q-2026-SM-718AQ
60-69 years, male
9.6
GTEX-1CAMQ-1426-SM-7MKFL
40-49 years, male
9.6
GTEX-ZVT3-1626-SM-5GU66
60-69 years, female
9.6
GTEX-1ICG6-1026-SM-B2LY6
70-79 years, female
9.6
GTEX-13FLV-0326-SM-5N9DJ
50-59 years, male
9.5
GTEX-ZVP2-0626-SM-51MSO
50-59 years, male
9.5
GTEX-1E2YA-1226-SM-7MGY3
50-59 years, male
9.5
GTEX-1HBPH-2626-SM-A96TV
40-49 years, female
9.5
GTEX-1JJEA-1526-SM-CNNPK
60-69 years, male
9.5
GTEX-131XH-0626-SM-5LZWH
50-59 years, male
9.4
GTEX-11NUK-1226-SM-5P9GM
50-59 years, male
9.3
GTEX-12WSM-0726-SM-5GCOW
60-69 years, male
9.3
GTEX-18A66-2026-SM-7189C
60-69 years, male
9.3
GTEX-WFON-1726-SM-4LVMQ
40-49 years, male
9.3
GTEX-YECK-1926-SM-4W21H
60-69 years, male
9.3
GTEX-11ZTS-1426-SM-5EQMM
60-69 years, female
9.2
GTEX-12WSL-0226-SM-5CVMJ
50-59 years, male
9.2
GTEX-12ZZZ-1326-SM-59HKW
60-69 years, male
9.2
GTEX-ZAB5-0426-SM-5CVMI
50-59 years, male
9.2
GTEX-1I1GR-1526-SM-CNNQE
60-69 years, male
9.2
GTEX-1KANB-2226-SM-DHXJW
50-59 years, male
9.2
GTEX-17MF6-1126-SM-7DUFS
40-49 years, male
9.1
GTEX-1B932-1426-SM-793AN
40-49 years, female
9.1
GTEX-1HB9E-0626-SM-AHZ4K
50-59 years, male
9.1
GTEX-12WSI-0226-SM-5GCNA
50-59 years, male
9.0
GTEX-14DAQ-1726-SM-5S2R2
60-69 years, female
9.0
GTEX-1JJ6O-0826-SM-CXZJL
60-69 years, male
9.0
GTEX-12KS4-1326-SM-5LUB3
30-39 years, male
8.9
GTEX-132NY-0926-SM-5P9G3
60-69 years, male
8.9
GTEX-P78B-1326-SM-3P611
40-49 years, female
8.9
GTEX-T6MN-1226-SM-3NMA5
50-59 years, male
8.9
GTEX-X261-1726-SM-4PQYT
50-59 years, male
8.9
GTEX-1QP66-0226-SM-DPRXS
50-59 years, male
8.9
GTEX-12WSD-1426-SM-5GCN9
60-69 years, female
8.8
GTEX-139YR-0226-SM-5IFEM
50-59 years, male
8.8
GTEX-14E7W-1526-SM-6871X
70-79 years, male
8.8
GTEX-17EVP-1026-SM-7IGOZ
40-49 years, male
8.8
GTEX-WK11-1326-SM-4OOSI
50-59 years, male
8.8
GTEX-WVLH-2126-SM-EYYWD
50-59 years, male
8.8
GTEX-13NZ9-1326-SM-5MR3V
50-59 years, male
8.7
GTEX-14PJO-1726-SM-68719
60-69 years, male
8.7
GTEX-WZTO-0626-SM-4PQYY
40-49 years, male
8.7
GTEX-ZAB4-0826-SM-5LU9D
40-49 years, male
8.7
GTEX-1H11D-0826-SM-9OSWB
40-49 years, male
8.7
GTEX-11OF3-0726-SM-5BC4Z
60-69 years, male
8.6
GTEX-1HBPI-1026-SM-AHZ4N
50-59 years, male
8.6
GTEX-ZYT6-0626-SM-5E45V
30-39 years, male
8.5
GTEX-1RQEC-1126-SM-EAZ5E
60-69 years, male
8.5
GTEX-131YS-1626-SM-5HL6C
60-69 years, female
8.4
GTEX-1S5VW-1826-SM-EAZ53
60-69 years, male
8.4
GTEX-139TU-0826-SM-5IJFG
60-69 years, male
8.3
GTEX-145LU-1326-SM-5LU9N
50-59 years, male
8.3
GTEX-148VI-0626-SM-5TDDH
60-69 years, female
8.3
GTEX-1HCU7-1726-SM-B2LX9
50-59 years, male
8.3
GTEX-1PBJJ-0626-SM-DPRYO
30-39 years, male
8.3
GTEX-15SHU-1826-SM-7KUKS
40-49 years, female
8.2
GTEX-1EWIQ-0726-SM-7MKFW
70-79 years, female
8.2
GTEX-Q734-0326-SM-48U15
40-49 years, female
8.2
GTEX-QV44-0326-SM-C1YQX
50-59 years, male
8.2
GTEX-144GM-1326-SM-5LU5E
20-29 years, male
8.1
GTEX-1PIIG-1326-SM-EXOIR
30-39 years, male
8.1
GTEX-P44G-1126-SM-3NM9D
30-39 years, male
8.0
GTEX-1F75A-1626-SM-9JGGT
50-59 years, male
8.0
GTEX-14JG1-1626-SM-664NH
40-49 years, male
7.9
GTEX-ZF2S-3026-SM-4WWCH
50-59 years, female
7.9
GTEX-14PHX-0526-SM-664NW
50-59 years, male
7.8
GTEX-1HCVE-1526-SM-B2LWW
50-59 years, male
7.8
GTEX-1J8EW-1626-SM-C1YQ8
60-69 years, female
7.8
GTEX-PX3G-0826-SM-48TZS
20-29 years, female
7.7
GTEX-RNOR-1426-SM-48FDJ
50-59 years, female
7.7
GTEX-139TS-1426-SM-5IFJD
60-69 years, male
7.6
GTEX-144GL-1426-SM-79OMA
50-59 years, male
7.5
GTEX-12696-0826-SM-5EGGE
60-69 years, male
7.4
GTEX-1AX8Z-1026-SM-7189R
60-69 years, male
7.4
GTEX-1KD5A-1226-SM-CXZK7
50-59 years, male
7.4
GTEX-11DXY-0526-SM-5EGGQ
60-69 years, male
7.3
GTEX-QEL4-1226-SM-447A4
50-59 years, male
7.2
GTEX-RU72-1426-SM-46MUF
50-59 years, female
7.2
GTEX-UPK5-1426-SM-4JBHH
40-49 years, male
7.2
GTEX-13N2G-0926-SM-5IFGJ
60-69 years, male
7.1
GTEX-13NZB-0626-SM-5IFH6
30-39 years, male
7.1
GTEX-VUSG-0126-SM-4KL1X
50-59 years, male
7.1
GTEX-XBEC-1526-SM-4AT68
50-59 years, male
7.1
GTEX-1399T-0826-SM-5IFES
60-69 years, male
7.0
GTEX-WYVS-1926-SM-4PQZ2
40-49 years, female
7.0
GTEX-13VXU-0926-SM-5IFFH
50-59 years, male
6.9
GTEX-13X6J-1826-SM-5TDCT
50-59 years, male
6.9
GTEX-S33H-1626-SM-4AD68
30-39 years, male
6.9
GTEX-1K9T9-0726-SM-CXZJZ
50-59 years, female
6.9
GTEX-Y111-0726-SM-EYYVM
50-59 years, male
6.9
GTEX-TKQ2-1726-SM-4DXUP
50-59 years, male
6.8
GTEX-11DXZ-0126-SM-5EGGY
50-59 years, male
6.7
GTEX-15DYW-1326-SM-6LPIV
60-69 years, female
6.7
GTEX-1B933-1226-SM-731DW
50-59 years, female
6.7
GTEX-11WQC-0726-SM-5EQMR
60-69 years, male
6.6
GTEX-1MJIX-0726-SM-DPRYP
40-49 years, male
6.6
GTEX-147GR-1326-SM-7IGLB
60-69 years, male
6.5
GTEX-1KD4Q-1526-SM-D4P3L
40-49 years, male
6.4
GTEX-1GF9X-0426-SM-7MKHN
40-49 years, female
6.1
GTEX-17HGU-1826-SM-7IGQM
50-59 years, male
5.8
GTEX-UTHO-2426-SM-4JBHD
60-69 years, male
5.6
GTEX-1B8SG-1326-SM-79ONT
50-59 years, male
5.3
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LIVER - FANTOM5 CAGEi
RNA expression in human tissues obtained through Cap Analysis of Gene Expression (CAGE) generated by the FANTOM5 project are reported as Scaled Tags Per Million.
The Human Protein Atlas project is funded
