NOX1

GENERAL INFORMATION

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Gene name

NOX1

Gene description

NADPH oxidase 1

Protein class

Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins
Transporters

Predicted localization

Intracellular,Membrane

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (colon, rectum)
GTEx:Tissue enriched (colon)

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA035299 , HPA035300
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (colon, rectum)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (colon)

Organ

Expression



GENE INFORMATION

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Gene name

NOX1 (HGNC Symbol)

Synonyms

GP91-2, MOX1, NOH-1, NOH1

Description

NADPH oxidase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]

Chromosome

X

Cytoband

q22.1

Chromosome location (bp)

100843324 - 100874345

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000007952 (version 78.38)

Entrez gene

27035

UniProt

Q9Y5S8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5S8

Antibodypedia

NOX1 antibodies


PROTEIN BROWSER

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ENST00000217885
 
ENST00000372960
 
ENST00000372964
 
ENST00000372966
 
ENST00000427768
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NOX1-001 ENSP00000362057
ENST00000372966
Q9Y5S8
Show all »
Show » Show » 564 64.9 No 7
NOX1-002 ENSP00000362055
ENST00000372964
Q5H9D4
Show all »
Show » Show » 192 22 No 4
NOX1-003 ENSP00000217885
ENST00000217885
Q9Y5S8
Show all »
Show » Show » 515 59 No 7
NOX1-004 ENSP00000396992
ENST00000427768
Show » Show » 175 20.3 No 0
NOX1-201 ENSP00000362051
ENST00000372960
A6NGA6
Show all »
Show » Show » 527 60.9 No 6