SH2D2A

GENERAL INFORMATION

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Gene name

SH2D2A

Gene description

SH2 domain containing 2A

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (appendix)
GTEx:Tissue enhanced (spleen)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (appendix)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (spleen)

Organ

Expression



GENE INFORMATION

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Gene name

SH2D2A (HGNC Symbol)

Synonyms

F2771, TSAd

Description

SH2 domain containing 2A (HGNC Symbol)

Entrez gene summary

This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]

Chromosome

1

Cytoband

q23.1

Chromosome location (bp)

156806243 - 156816862

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000027869 (version 78.38)

Entrez gene

9047

UniProt

Q9NP31 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NP31

Antibodypedia

SH2D2A antibodies


PROTEIN BROWSER

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ENST00000368198
 
ENST00000368199
 
ENST00000392306
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SH2D2A-001 ENSP00000357182
ENST00000368199
Q9NP31
Show all »
Show » Show » 389 42.9 No 0
SH2D2A-002 ENSP00000357181
ENST00000368198
Q9NP31
Show all »
Show » Show » 371 41 No 0
SH2D2A-201 ENSP00000376123
ENST00000392306
Q9NP31
Show all »
Show » Show » 399 44.1 No 0