STAP1

GENERAL INFORMATION

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Gene name

STAP1

Gene description

Signal transducing adaptor family member 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (lymph node, tonsil)
GTEx:Tissue enhanced (kidney, small intestine, spleen)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in a subset of immune cells.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA038529
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Nasopharynx
N/A
N/A
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (lymph node, tonsil)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (kidney, small intestine, spleen)

Organ

Expression



GENE INFORMATION

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Gene name

STAP1 (HGNC Symbol)

Synonyms

BRDG1, STAP-1

Description

Signal transducing adaptor family member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity. [provided by RefSeq, Jul 2008]

Chromosome

4

Cytoband

q13.2

Chromosome location (bp)

67558728 - 67607337

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000035720 (version 78.38)

Entrez gene

26228

UniProt

Q9ULZ2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9ULZ2

Antibodypedia

STAP1 antibodies


PROTEIN BROWSER

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ENST00000265404
 
ENST00000396225
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STAP1-001 ENSP00000265404
ENST00000265404
Q9ULZ2
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Show » Show » 295 34.3 No 0
STAP1-002 ENSP00000379527
ENST00000396225
Q9ULZ2
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Show » Show » 295 34.3 No 0