ACAA1

GENERAL INFORMATION

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Gene name

ACAA1

Gene description

Acetyl-CoA acyltransferase 1

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in most glandular cells. Distinct expression in hepatocytes, heart muscle and neuronal cells in CNS.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Supportive based on 2 antibodies.
HPA006764 , HPA007244
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ACAA1

Synonyms

Description

Acetyl-CoA acyltransferase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme operative in the beta-oxidation system of the peroxisomes. Deficiency of this enzyme leads to pseudo-Zellweger syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]

Chromosome

3

Cytoband

p22.2

Chromosome location (bp)

38103129 - 38137242

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000060971 (version 78.38)

Entrez gene

30

UniProt

P09110 (UniProt - Evidence at protein level)

neXtProt

NX_P09110

Antibodypedia

ACAA1 antibodies


PROTEIN BROWSER

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ENST00000301810
 
ENST00000333167
 
ENST00000421218
 
ENST00000450296
 
ENST00000452171
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACAA1-001 ENSP00000333664
ENST00000333167
P09110
Show all »
Show » Show » 424 44.3 No 0
ACAA1-002 ENSP00000301810
ENST00000301810
P09110
Show all »
Show » Show » 331 34.7 No 0
ACAA1-007 ENSP00000395183
ENST00000450296
C9JDE9
Show all »
Show » Show » 383 40.3 No 0
ACAA1-014 ENSP00000398172
ENST00000421218
Show » Show » 290 30.2 No 0
ACAA1-019 ENSP00000391078
ENST00000452171
Show » Show » 237 24.9 No 0