AHRR

GENERAL INFORMATION

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Gene name

AHRR

Gene description

Aryl-hydrocarbon receptor repressor

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

9
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enhanced (testis)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in testis. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 2 antibodies.
HPA019614 , HPA021483
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression



GENE INFORMATION

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Gene name

AHRR (HGNC Symbol)

Synonyms

AHH, AHHR, bHLHe77, KIAA1234

Description

Aryl-hydrocarbon receptor repressor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene participates in the aryl hydrocarbon receptor (AhR) signaling cascade, which mediates dioxin toxicity, and is involved in regulation of cell growth and differentiation. It functions as a feedback modulator by repressing AhR-dependent gene expression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jun 2011]

Chromosome

5

Cytoband

p15.33

Chromosome location (bp)

304176 - 438291

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000063438 (version 78.38)

Entrez gene

57491

UniProt

A9YTQ3 (UniProt - Evidence at transcript level)

neXtProt

NX_A9YTQ3

Antibodypedia

AHRR antibodies


PROTEIN BROWSER

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ENST00000316418
 
ENST00000504625
 
ENST00000505113
 
ENST00000506456
 
ENST00000510400
 
ENST00000511487
 
ENST00000512529
 
ENST00000514523
 
ENST00000515206
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AHRR-001 ENSP00000323816
ENST00000316418
A9YTQ3
Show all »
Show » Show » 719 78.3 No 0
AHRR-002 ENSP00000424601
ENST00000505113
A9YTQ3
Show all »
Show » Show » 701 76.3 No 0
AHRR-003 ENSP00000424880
ENST00000512529
D6RF73
Show all »
Show » 547 59.4 No 0
AHRR-004 ENSP00000426932
ENST00000506456
D6RE68
Show all »
Show » 557 60.5 No 0
AHRR-006 ENSP00000430914
ENST00000514523
Show » 12 1.5 No 0
AHRR-007 ENSP00000428893
ENST00000510400
E5RFG4
Show all »
Show » Show » 157 17.3 No 0
AHRR-008 ENSP00000429944
ENST00000504625
E5RGQ2
Show all »
Show » Show » 81 9.3 No 0
AHRR-009 ENSP00000430842
ENST00000515206
G3V143
Show all »
Show » Show » 139 15.7 No 0
AHRR-011 ENSP00000426076
ENST00000511487
H0YA43
Show all »
Show » 215 23.3 No 0