The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Moderate cytoplasmic positivity was observed in respiratory epithelia, hepatocytes, gall bladder, renal tubules, urothelia, epididymis, heart muscle and neuronal cells in CNS. Skeletal muscles and neuropil in the CNS were strongly stained. Remaining tissues were in general weakly stained or negative.
A subset of cells in red pulp of spleen and non-germinal center cells of lymphoid tissues were strongly stained. Neuropil were distinctly stained. Respiratory epithelia, large intestine, renal tubules, ovarian follicles, endometrial glands, cells in CNS and plasma showed weak to moderate staining. Remaining normal tissues were mainly negative.
Moderate to strong positivity was observed in follicle cells, prostate, subsets of cells in CNS and lymphoid tissues. Neuropil were distinctly stained. Remaining normal tissues were weakly stained or negative.