PRKCQ

GENERAL INFORMATION

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Gene name

PRKCQ

Gene description

Protein kinase C, theta

Protein class

Cancer-related genes
Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (skeletal muscle)
GTEx:Tissue enhanced (skeletal muscle)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (skeletal muscle)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (skeletal muscle)

Organ

Expression



GENE INFORMATION

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Gene name

PRKCQ

Synonyms

Description

Protein kinase C, theta (HGNC Symbol)

Entrez gene summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors. [provided by RefSeq, Jul 2008]

Chromosome

10

Cytoband

p15.1

Chromosome location (bp)

6427143 - 6580301

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000065675 (version 78.38)

Entrez gene

5588

UniProt

Q04759 (UniProt - Evidence at protein level)

neXtProt

NX_Q04759

Antibodypedia

PRKCQ antibodies


PROTEIN BROWSER

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ENST00000263125
 
ENST00000397176
 
ENST00000539722
 
ENST00000610727
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRKCQ-001 ENSP00000263125
ENST00000263125
Q04759
Show all »
Show » Show » 706 81.9 No 0
PRKCQ-201 ENSP00000380361
ENST00000397176
Q04759
Show all »
Show » Show » 643 74.3 No 0
PRKCQ-202 ENSP00000441752
ENST00000539722
Q04759
Show all »
Show » Show » 581 67.6 No 0
PRKCQ-203 ENSP00000483428
ENST00000610727
Show » Show » 670 78 No 0