NEDD4

GENERAL INFORMATION

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Gene name

NEDD4

Gene description

Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase

Protein class

Predicted intracellular proteins
Transporters

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Tissue enhanced (skeletal muscle)

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 3 antibodies.
HPA039883 , CAB001991 , CAB072833
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (skeletal muscle)

Organ

Expression



GENE INFORMATION

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Gene name

NEDD4 (HGNC Symbol)

Synonyms

KIAA0093, MGC176705, NEDD4-1, RPF1

Description

Neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

Chromosome

15

Cytoband

q21.3

Chromosome location (bp)

55826922 - 55993746

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000069869 (version 78.38)

Entrez gene

4734

UniProt

P46934 (UniProt - Evidence at protein level)

neXtProt

NX_P46934

Antibodypedia

NEDD4 antibodies


PROTEIN BROWSER

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ENST00000338963
 
ENST00000435532
 
ENST00000506154
 
ENST00000508342
 
ENST00000508871
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NEDD4-001 ENSP00000345530
ENST00000338963
P46934
Show all »
Show » Show » 1247 140.7 No 0
NEDD4-002 ENSP00000424827
ENST00000508342
P46934
Show all »
Show » Show » 1319 149.1 No 0
NEDD4-003 ENSP00000422705
ENST00000506154
P46934
Show all »
Show » Show » 1303 147.4 No 0
NEDD4-004 ENSP00000422455
ENST00000508871
Show » Show » 910 104.7 No 0
NEDD4-006 ENSP00000410613
ENST00000435532
P46934
Show all »
Show » Show » 900 104.2 No 0