NFATC3

GENERAL INFORMATION

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Gene name

NFATC3

Gene description

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic and occasional nuclear expression in most tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data.

Data reliability

Uncertain based on 2 antibodies.
HPA023844 , CAB004514
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

NFATC3 (HGNC Symbol)

Synonyms

NFAT4, NFATX

Description

Nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 (HGNC Symbol)

Entrez gene summary

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate to form this complex also. The product of this gene plays a role in the regulation of gene expression in T cells and immature thymocytes. Several transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2010]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

68084751 - 68229259

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000072736 (version 78.38)

Entrez gene

4775

UniProt

Q12968 (UniProt - Evidence at protein level)

neXtProt

NX_Q12968

Antibodypedia

NFATC3 antibodies


PROTEIN BROWSER

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ENST00000329524
 
ENST00000346183
 
ENST00000349223
 
ENST00000562926
 
ENST00000565750
 
ENST00000570212
 
ENST00000575270
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NFATC3-001 ENSP00000264008
ENST00000349223
Q12968
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Show » Show » 1065 115.1 No 0
NFATC3-002 ENSP00000300659
ENST00000346183
Q12968
Show all »
Show » Show » 1075 115.6 No 0
NFATC3-003 ENSP00000331324
ENST00000329524
Q12968
Show all »
Show » Show » 1068 115.2 No 0
NFATC3-016 ENSP00000456379
ENST00000570212
B5B2S4
Show all »
Show » Show » 1060 114.2 No 0
NFATC3-017 ENSP00000456120
ENST00000562926
B5B2S3
Show all »
Show » Show » 1053 113.9 No 0
NFATC3-023 ENSP00000460533
ENST00000575270
I3L3K7
Show all »
Show » Show » 1047 112.8 No 0
NFATC3-024 ENSP00000457441
ENST00000565750
H3BU30
Show all »
Show » Show » 167 18.5 No 0