ARHGEF10L

GENERAL INFORMATION

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Gene name

ARHGEF10L

Gene description

Rho guanine nucleotide exchange factor (GEF) 10-like

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic expression with a granular pattern.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA026426 , HPA026440 , HPA028115
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ARHGEF10L (HGNC Symbol)

Synonyms

FLJ10521, KIAA1626

Description

Rho guanine nucleotide exchange factor (GEF) 10-like (HGNC Symbol)

Entrez gene summary

ARHGEF10L is a member of the RhoGEF family of guanine nucleotide exchange factors (GEFs) that activate Rho GTPases (Winkler et al., 2005 [PubMed 16112081]).[supplied by OMIM, Dec 2008]

Chromosome

1

Cytoband

p36.13

Chromosome location (bp)

17539835 - 17697874

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000074964 (version 78.38)

Entrez gene

55160

UniProt

Q9HCE6 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HCE6

Antibodypedia

ARHGEF10L antibodies


PROTEIN BROWSER

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ENST00000361221
 
ENST00000375408
 
ENST00000375415
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGEF10L-001 ENSP00000355060
ENST00000361221
Q9HCE6
Show all »
Show » Show » 1279 140.4 No 0
ARHGEF10L-002 ENSP00000364557
ENST00000375408
Show » Show » 1052 115.6 No 0
ARHGEF10L-003 ENSP00000364564
ENST00000375415
Q9HCE6
Show all »
Show » Show » 1240 135.7 No 0