The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Strong cytoplasmic staining macrophages, endothelial and glial cells in CNS. Additional staining was seen in most squamous epithelia. Remaining cells were mainly negative.
Strong cytoplasmic positivity was observed in monocyte-derived cells, ovarian follicle cells and placental decidual cells. Moderate staining was displayed in several tissues including testis, breast, endothelial cells, squamous epithelia, respiratory tract, neuropil, peripheral nerves and lymph nodes. Most remaining normal tissues were weakly stained or negative.
Most normal cells were negative. Cells in testis and basal cells in urinary bladder showed strong cytoplasmic positivity.
Moderate to strong cytoplasmic staining in most tissues. Strongest staining in subsets of immune cells, fibroblasts, endothelial cells and squamous epithelia.