SCTR

GENERAL INFORMATION

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Gene name

SCTR

Gene description

Secretin receptor

Protein class

FDA approved drug targets
G-protein coupled receptors
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

1
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (duodenum, lung, pancreas)
GTEx:Tissue enriched (pancreas)

Protein evidence

Evidence at protein level

Protein localization

Membranous expression in several different tissue types.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA007269
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (duodenum, lung, pancreas)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (pancreas)

Organ

Expression



GENE INFORMATION

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Gene name

SCTR

Synonyms

Description

Secretin receptor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a G protein-coupled receptor and belongs to the glucagon-VIP-secretin receptor family. It binds secretin which is the most potent regulator of pancreatic bicarbonate, electrolyte and volume secretion. Secretin and its receptor are suggested to be involved in pancreatic cancer and autism. [provided by RefSeq, Jul 2008]

Chromosome

2

Cytoband

q14.2

Chromosome location (bp)

119439843 - 119524494

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000080293 (version 78.38)

Entrez gene

6344

UniProt

P47872 (UniProt - Evidence at transcript level)

neXtProt

NX_P47872

Antibodypedia

SCTR antibodies


PROTEIN BROWSER

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ENST00000019103
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SCTR-001 ENSP00000019103
ENST00000019103
P47872
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