RFX3

GENERAL INFORMATION

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Gene name

RFX3

Gene description

Regulatory factor X, 3 (influences HLA class II expression)

Protein class

Predicted intracellular proteins
Transcription factors

Predicted localization

Intracellular

Number of transcripts

12
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (testis)
GTEx:Mixed

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression in testis.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA035689
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Mixed

Organ

Expression



GENE INFORMATION

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Gene name

RFX3

Synonyms

Description

Regulatory factor X, 3 (influences HLA class II expression) (HGNC Symbol)

Entrez gene summary

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2013]

Chromosome

9

Cytoband

p24.2

Chromosome location (bp)

3218297 - 3526004

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000080298 (version 78.38)

Entrez gene

5991

UniProt

P48380 (UniProt - Evidence at protein level)

neXtProt

NX_P48380

Antibodypedia

RFX3 antibodies


PROTEIN BROWSER

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ENST00000302303
 
ENST00000358730
 
ENST00000381984
 
ENST00000382004
 
ENST00000420720
 
ENST00000442560
 
ENST00000449190
 
ENST00000449234
 
ENST00000451859
 
ENST00000457373
 
ENST00000458034
 
ENST00000617270
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RFX3-001 ENSP00000371414
ENST00000381984
A9Z1Z2
Show all »
Show » Show » 85 9.1 No 0
RFX3-002 ENSP00000411756
ENST00000451859
F6UV76
Show all »
Show » Show » 184 19.4 No 0
RFX3-003 ENSP00000405664
ENST00000457373
F6UGA0
Show all »
Show » Show » 216 23.4 No 0
RFX3-004 ENSP00000399352
ENST00000449190
F6XM74
Show all »
Show » Show » 138 14.5 No 0
RFX3-005 ENSP00000351574
ENST00000358730
P48380
Show all »
Show » Show » 707 79.4 No 0
RFX3-006 ENSP00000371434
ENST00000382004
P48380
Show all »
Show » Show » 749 83.5 No 0
RFX3-007 ENSP00000415594
ENST00000449234
H0Y7W5
Show all »
Show » 124 14.5 No 0
RFX3-008 ENSP00000400026
ENST00000458034
F6USP3
Show all »
Show » 174 19.9 No 0
RFX3-009 ENSP00000410988
ENST00000442560
H0Y790
Show all »
Show » Show » 135 14.3 No 0
RFX3-010 ENSP00000416189
ENST00000420720
H0Y7Z4
Show all »
Show » Show » 156 16.7 No 0
RFX3-201 ENSP00000303847
ENST00000302303
P48380
Show all »
Show » Show » 413 45.7 No 0
RFX3-202 ENSP00000482598
ENST00000617270
P48380
Show all »
Show » Show » 749 83.5 No 0