SGK2

GENERAL INFORMATION

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Gene name

SGK2

Gene description

Serum/glucocorticoid regulated kinase 2

Protein class

Enzymes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

7
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (kidney)
GTEx:Tissue enhanced (kidney, liver)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in several tissues.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA011387
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (kidney)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (kidney, liver)

Organ

Expression



GENE INFORMATION

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Gene name

SGK2

Synonyms

Description

Serum/glucocorticoid regulated kinase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a serine/threonine protein kinase. Although this gene product is similar to serum- and glucocorticoid-induced protein kinase (SGK), this gene is not induced by serum or glucocorticoids. This gene is induced in response to signals that activate phosphatidylinositol 3-kinase, which is also true for SGK. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010]

Chromosome

20

Cytoband

q13.12

Chromosome location (bp)

43558968 - 43588237

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101049 (version 78.38)

Entrez gene

10110

UniProt

Q9HBY8 (UniProt - Evidence at protein level)

neXtProt

NX_Q9HBY8

Antibodypedia

SGK2 antibodies


PROTEIN BROWSER

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ENST00000341458
 
ENST00000373092
 
ENST00000373100
 
ENST00000412111
 
ENST00000423407
 
ENST00000426287
 
ENST00000617268
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SGK2-001 ENSP00000362184
ENST00000373092
Q9HBY8
Show all »
Show » Show » 367 41.2 No 0
SGK2-002 ENSP00000340608
ENST00000341458
Q9HBY8
Show all »
Show » Show » 427 47.6 No 0
SGK2-005 ENSP00000362192
ENST00000373100
Q9HBY8
Show all »
Show » Show » 367 41.2 No 0
SGK2-007 ENSP00000396222
ENST00000412111
Q5H8Y5
Show all »
Show » Show » 198 22.1 No 0
SGK2-009 ENSP00000481432
ENST00000617268
Show » 10 0.9 No 0
SGK2-011 ENSP00000412214
ENST00000426287
Q9HBY8
Show all »
Show » Show » 393 44 No 0
SGK2-201 ENSP00000392795
ENST00000423407
Q9HBY8
Show all »
Show » Show » 367 41.2 No 0