BPI

GENERAL INFORMATION

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Gene name

BPI

Gene description

Bactericidal/permeability-increasing protein

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Predicted secreted proteins
Transporters

Predicted localization

Intracellular,Membrane,Secreted

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (bone marrow)
GTEx:Group enriched (spleen, testis)

Protein evidence

Evidence at protein level

Protein localization

Selective cytoplasmic expression in a fraction of hematopoietic cells and in subsets of leukocytes.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Supportive based on 1 antibody.
HPA061284
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Bone marrow

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (bone marrow)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (spleen, testis)

Organ

Expression



GENE INFORMATION

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Gene name

BPI (HGNC Symbol)

Synonyms

BPIFD1

Description

Bactericidal/permeability-increasing protein (HGNC Symbol)

Entrez gene summary

This gene encodes a lipopolysaccharide binding protein. It is associated with human neutrophil granules and has antimicrobial activity against gram-negative organisms. [provided by RefSeq, Nov 2014]

Chromosome

20

Cytoband

q11.23

Chromosome location (bp)

38260149 - 38337505

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101425 (version 78.38)

Entrez gene

671

UniProt

P17213 (UniProt - Evidence at protein level)

neXtProt

NX_P17213

Antibodypedia

BPI antibodies


PROTEIN BROWSER

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ENST00000262865
 
ENST00000417318
 
ENST00000418004
 
ENST00000451435
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BPI-001 ENSP00000409833
ENST00000417318
Show » Show » 313 34.5 No 0
BPI-002 ENSP00000262865
ENST00000262865
P17213
Show all »
Show » Show » 487 53.9 Yes 0
BPI-006 ENSP00000393126
ENST00000418004
A2A2A2
Show all »
Show » 123 13.2 No 1
BPI-008 ENSP00000391511
ENST00000451435
A2A2A1
Show all »
Show » 95 10 No 0