The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Moderate to strong cytoplasmic and nuclear positivity was observed in neuronal cells and hepatocytes. Purkinje cells and cells in molecular layer of cerebellum showed strong cytoplasmic staining. Islets of Langerhans, adrenal gland and Leydig cells were moderately stained. Remaining normal tissues were negative.
Neuronal cells in CNS and a subset of renal tubules showed strong cytoplasmic positivity. Superficial cells in squamous epithelia displayed moderate staining. Other normal tissues were negative.
Neuronal cells displayed strong cytoplasmic staining. Purkinje cells, small intestine, fraction of skeletal muscle cells, thyroid gland, adrenal gland, heart myocytes and Leydig cells showed weak to moderate staining. Remaining normal tissues were negative.
The neuronal cells and Purkinje cells showed strong cytoplasmic staining. Stomach and duodenum displayed moderate positivity. Remaining normal tissues were negative.