PIGU

GENERAL INFORMATION

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Gene name

PIGU

Gene description

Phosphatidylinositol glycan anchor biosynthesis, class U

Protein class

Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in glandular epithelia.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 2 antibodies.
HPA041706 , HPA046766
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PIGU (HGNC Symbol)

Synonyms

bA346K17.2, CDC91L1, GAB1

Description

Phosphatidylinositol glycan anchor biosynthesis, class U (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene shares similarity with Saccharomyces cerevisiae Cdc91, a predicted integral membrane protein that may function in cell division control. The protein encoded by this gene is the fifth subunit of GPI transamidase that attaches GPI-anchors to proteins. [provided by RefSeq, Jul 2008]

Chromosome

20

Cytoband

q11.22

Chromosome location (bp)

34560542 - 34677090

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101464 (version 78.38)

Entrez gene

128869

UniProt

Q9H490 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H490

Antibodypedia

PIGU antibodies


PROTEIN BROWSER

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ENST00000217446
 
ENST00000374820
 
ENST00000438215
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PIGU-001 ENSP00000217446
ENST00000217446
Q9H490
Show all »
Show » Show » 435 50.1 Yes >9
PIGU-004 ENSP00000395755
ENST00000438215
Q5JWU1
Show all »
Show » Show » 170 19.7 No 5
PIGU-201 ENSP00000363953
ENST00000374820
Q9H490
Show all »
Show » Show » 415 47.6 Yes >9