PSMD10

GENERAL INFORMATION

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Gene name

PSMD10

Gene description

Proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic and nuclear expression, most abundant in seminiferous duct cells.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA002920 , CAB010434
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Adrenal gland

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PSMD10 (HGNC Symbol)

Synonyms

p28

Description

Proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.[provided by RefSeq, Mar 2011]

Chromosome

X

Cytoband

q22.3

Chromosome location (bp)

108084207 - 108091618

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000101843 (version 78.38)

Entrez gene

5716

UniProt

O75832 (UniProt - Evidence at protein level)

neXtProt

NX_O75832

Antibodypedia

PSMD10 antibodies


PROTEIN BROWSER

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ENST00000217958
 
ENST00000340200
 
ENST00000361815
 
ENST00000372295
 
ENST00000372296
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PSMD10-001 ENSP00000217958
ENST00000217958
O75832
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Show » Show » 226 24.4 No 0
PSMD10-002 ENSP00000354906
ENST00000361815
O75832
Show all »
Show » Show » 151 16.1 No 0
PSMD10-004 ENSP00000361369
ENST00000372295
B1AJY5
Show all »
Show » Show » 185 20.2 No 0
PSMD10-005 ENSP00000361370
ENST00000372296
B1AJY6
Show all »
Show » Show » 110 11.9 No 0
PSMD10-006 ENSP00000345963
ENST00000340200
B1AJY7
Show all »
Show » Show » 193 20.8 No 0