CDIPT

GENERAL INFORMATION

? »

Gene name

CDIPT

Gene description

CDP-diacylglycerol--inositol 3-phosphatidyltransferase

Protein class

Enzymes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

6
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues showed weak to moderate cytoplasmic staining. Respiratory epithelia, colon, rectum and epidydimis displayed additional membranous positivity.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA056597
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

CDIPT (HGNC Symbol)

Synonyms

PIS, PIS1

Description

CDP-diacylglycerol--inositol 3-phosphatidyltransferase (HGNC Symbol)

Entrez gene summary

Phosphatidylinositol breakdown products are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. Two enzymes, CDP-diacylglycerol synthase and phosphatidylinositol synthase, are involved in the biosynthesis of phosphatidylinositol. Phosphatidylinositol synthase, a member of the CDP-alcohol phosphatidyl transferase class-I family, is an integral membrane protein found on the cytoplasmic side of the endoplasmic reticulum and the Golgi apparatus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

Chromosome

16

Cytoband

p11.2

Chromosome location (bp)

29858357 - 29863736

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000103502 (version 78.38)

Entrez gene

10423

UniProt

O14735 (UniProt - Evidence at protein level)

neXtProt

NX_O14735

Antibodypedia

CDIPT antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000219789
 
ENST00000561555
 
ENST00000563415
 
ENST00000566113
 
ENST00000569956
 
ENST00000570016
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDIPT-001 ENSP00000219789
ENST00000219789
O14735
Show all »
Show » Show » 213 23.5 No 5
CDIPT-003 ENSP00000457340
ENST00000566113
O14735
Show all »
Show » Show » 168 18.6 No 3
CDIPT-004 ENSP00000454453
ENST00000570016
O14735
Show all »
Show » Show » 213 23.5 No 5
CDIPT-005 ENSP00000455042
ENST00000561555
B3KY94
Show all »
Show » Show » 237 25.9 Yes 3
CDIPT-007 ENSP00000457339
ENST00000569956
O14735
Show all »
Show » Show » 213 23.5 No 5
CDIPT-009 ENSP00000457766
ENST00000563415
H3BUR9
Show all »
Show » Show » 157 17.3 No 3