EPHB6

GENERAL INFORMATION

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Gene name

EPHB6

Gene description

EPH receptor B6

Protein class

Predicted intracellular proteins
Predicted membrane proteins

Predicted localization

Intracellular,Membrane

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (skin)
GTEx:Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

EPHB6 (HGNC Symbol)

Synonyms

HEP

Description

EPH receptor B6 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of transmembrane proteins that function as receptors for ephrin-B family proteins. Unlike other members of this family, the encoded protein does not contain a functional kinase domain. Activity of this protein can influence cell adhesion and migration. Expression of this gene is downregulated during tumor progression, suggesting that the protein may suppress tumor invasion and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

7

Cytoband

q34

Chromosome location (bp)

142855061 - 142871094

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106123 (version 78.38)

Entrez gene

2051

UniProt

neXtProt

Antibodypedia

EPHB6 antibodies


PROTEIN BROWSER

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ENST00000411471
 
ENST00000422643
 
ENST00000476059
 
ENST00000619012
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHB6-001 ENSP00000481994
ENST00000619012
Show » Show » 1022 110.8 Yes 2
EPHB6-006 ENSP00000481996
ENST00000476059
Show » Show » 112 12.8 No 0
EPHB6-201 ENSP00000409061
ENST00000411471
Show » Show » 729 79.8 No 1
EPHB6-202 ENSP00000404786
ENST00000422643
Show » Show » 1022 110.8 Yes 2