AGR2

GENERAL INFORMATION

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Gene name

AGR2

Gene description

Anterior gradient 2

Protein class

Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (rectum, stomach)
GTEx:Tissue enhanced (colon, salivary gland, stomach)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in several tissues, including glands in GI, and in female and male genitalia.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Data reliability

Supportive based on 1 antibody.
HPA007912
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Prostate



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (rectum, stomach)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (colon, salivary gland, stomach)

Organ

Expression



GENE INFORMATION

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Gene name

AGR2 (HGNC Symbol)

Synonyms

AG2, HAG-2, PDIA17, XAG-2

Description

Anterior gradient 2 (HGNC Symbol)

Entrez gene summary

Chromosome

7

Cytoband

p21.1

Chromosome location (bp)

16791811 - 16833433

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000106541 (version 78.38)

Entrez gene

10551

UniProt

O95994 (UniProt - Evidence at protein level)

neXtProt

NX_O95994

Antibodypedia

AGR2 antibodies


PROTEIN BROWSER

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ENST00000401412
 
ENST00000412973
 
ENST00000419304
 
ENST00000450569
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGR2-001 ENSP00000391490
ENST00000419304
O95994
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Show » Show » 175 20 Yes 0
AGR2-005 ENSP00000386025
ENST00000401412
B5MC07
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Show » 188 21.4 Yes 0
AGR2-006 ENSP00000414806
ENST00000450569
H7C3Z9
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Show » 119 13.5 No 0
AGR2-007 ENSP00000411969
ENST00000412973
C9J3E2
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Show » 131 15 Yes 0