The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Weak to moderate granular cytoplasmic staining in several tissues. Strong staining in pancreatic islets. Weaker staining in smooth muscle cells and blood vessels. CNS, lymphoid and most mesenchymal tissues were negative.
Strong membranous staining was seen in most blood vessels. Strong cytoplasmic and membranous staining was observed in placental trophoblasts and in ciliated cells in bronchus and fallopian tube. Remaining tissues were negative.
Moderate cytoplasmic and membranous staining of blood vessels. Distinct staining in spleen, placenta and glomeruli. Remaining normal cells were mainly negative.
Moderate to strong membranous and cytoplasmic staining of endothelial cells was observed in subsets of vessels. Cells in glomeruli were distinctly stained. Placental trophoblasts showed moderate membranous positivity. Remaining cells were negative.