KDM4C

GENERAL INFORMATION

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Gene name

KDM4C

Gene description

Lysine (K)-specific demethylase 4C

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

KDM4C (HGNC Symbol)

Synonyms

GASC1, JMJD2C, KIAA0780, TDRD14C

Description

Lysine (K)-specific demethylase 4C (HGNC Symbol)

Entrez gene summary

This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]

Chromosome

9

Cytoband

p24.1

Chromosome location (bp)

6757641 - 7175648

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000107077 (version 78.38)

Entrez gene

23081

UniProt

Q9H3R0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H3R0

Antibodypedia

KDM4C antibodies


PROTEIN BROWSER

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ENST00000381306
 
ENST00000381309
 
ENST00000401787
 
ENST00000420847
 
ENST00000428870
 
ENST00000543771
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KDM4C-001 ENSP00000370710
ENST00000381309
Q9H3R0
Show all »
Show » Show » 1056 120 No 0
KDM4C-002 ENSP00000370707
ENST00000381306
Q9H3R0
Show all »
Show » Show » 1047 118.4 No 0
KDM4C-006 ENSP00000400127
ENST00000420847
Show » Show » 354 39.5 No 0
KDM4C-010 ENSP00000383990
ENST00000401787
B0QZ60
Show all »
Show » 151 17.6 No 0
KDM4C-013 ENSP00000405739
ENST00000428870
C9J879
Show all »
Show » Show » 743 83.9 No 0
KDM4C-014 ENSP00000445427
ENST00000543771
Q9H3R0
Show all »
Show » Show » 813 91.9 No 0