DDX5 protein expression summary - The Human Protein Atlas

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DDX5

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HUMAN PROTEIN ATLAS SUMMARYⁱ General description of the gene and the encoded protein(s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project.
Proteinⁱ Full gene name according to HGNC.	DEAD-box helicase 5
Gene nameⁱ Official gene symbol, which is typically a short form of the gene name, according to HGNC.	DDX5 (G17P1, HLR1, p68)
Tissue specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected. Read more	Low tissue specificity
Single cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Blood specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed blood cell samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low immune cell specificity
Brain specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low human brain regional specificity
Cancer prognostic summary	Prognostic marker in colorectal cancer (favorable)
Predicted locationⁱ All transcripts of all genes have been analyzed regarding the location(s) of corresponding protein based on prediction methods for signal peptides and transmembrane regions. Genes with at least one transcript predicted to encode a secreted protein, according to prediction methods or to UniProt location data, have been further annotated and classified with the aim to determine if the corresponding protein(s) are secreted or actually retained in intracellular locations or membrane-attached. Remaining genes, with no transcript predicted to encode a secreted protein, will be assigned the prediction-based location(s). The annotated location overrules the predicted location, so that a gene encoding a predicted secreted protein that has been annotated as intracellular will have intracellular as the final location. Read more	Intracellular
Subcellular summaryⁱ The main location is characterized by presence in all tested cell lines and/or increased intensity compared to other locations. Additional locations are characterized by either a markedly lower staining intensity than the main location, or that it is only observed in a subset of the cell lines.	Located in Nucleoplasm, Nucleoli (Single cell variability)
Protein function (UniProt)ⁱ Useful information about the protein provided by UniProt.	Involved in the alternative regulation of pre-mRNA splicing; its RNA helicase activity is necessary for increasing tau exon 10 inclusion and occurs in a RBM4-dependent manner. Binds to the tau pre-mRNA in the stem-loop region downstream of exon 10. The rate of ATP hydrolysis is highly stimulated by single-stranded RNA. Involved in transcriptional regulation; the function is independent of the RNA helicase activity. Transcriptional coactivator for androgen receptor AR but probably not ESR1. Synergizes with DDX17 and SRA1 RNA to activate MYOD1 transcriptional activity and involved in skeletal muscle differentiation. Transcriptional coactivator for p53/TP53 and involved in p53/TP53 transcriptional response to DNA damage and p53/TP53-dependent apoptosis. Transcriptional coactivator for RUNX2 and involved in regulation of osteoblast differentiation. Acts as transcriptional repressor in a promoter-specific manner; the function probably involves association with histone deacetylases, such as HDAC1. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms.... show less
Molecular function (UniProt)ⁱ Keywords assigned by UniProt to proteins due to their particular molecular function.	Helicase, Hydrolase, RNA-binding
Biological process (UniProt)ⁱ Keywords assigned by UniProt to proteins because they are involved in a particular biological process.	Biological rhythms, mRNA processing, mRNA splicing, Transcription, Transcription regulation
Disease involvementⁱ Disease related keywords assigned by UniProt combined with Cancer-related genes and FDA approved drug targets Read more	Cancer-related genes
Ligand (UniProt)ⁱ Keywords assigned by UniProt to proteins because they bind, are associated with, or whose activity is dependent of some molecule.	ATP-binding, Nucleotide-binding
Gene summary (Entrez)ⁱ Useful information about the gene from Entrez	This gene encodes a member of the DEAD box family of RNA helicases that are involved in a variety of cellular processes as a result of its role as an adaptor molecule, promoting interactions with a large number of other factors. This protein is involved in pathways that include the alteration of RNA structures, plays a role as a coregulator of transcription, a regulator of splicing, and in the processing of small noncoding RNAs. Members of this family contain nine conserved motifs, including the conserved Asp-Glu-Ala-Asp (DEAD) motif, important to ATP binding and hydrolysis as well as RNA binding and unwinding activities. Dysregulation of this gene may play a role in cancer development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2017]... show less

TISSUE ATLASⁱ Summary of data presented in the Tissue Atlas and representative images of protein expression (left) and mRNA expression (right). The images are clickable and will redirect to more Tissue Atlas data. The Tissue Atlas contains information regarding the expression profiles of protein-coding genes in normal human tissue, both on the mRNA and protein level. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry. Read more

Tissue specificity (RNA)ⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: tissue enriched, group enriched, tissue enhanced, low tissue specificity and not detected. Read more	Low tissue specificity
Tissue distribution (RNA)ⁱ The RNA distribution category is based on mRNA expression levels in the analyzed samples based on a combination of data from HPA, GTEX and FANTOM5. The categories include: detected in all, detected in many, detected in some, detected in single and not detected. Read more	Detected in all
Protein expressionⁱ A summary of the overall protein expression pattern across the analyzed normal tissues. The summary is based on knowledge-based annotation. "Estimation of protein expression could not be performed. View primary data." is shown for genes analyzed with a knowledge-based approach where available RNA-seq and gene/protein characterization data has been evaluated as not sufficient in combination with immunohistochemistry data to yield a reliable estimation of the protein expression profile. Read more	Ubiquitous nuclear and cytoplasmic expression.

SINGLE CELL TYPE ATLASⁱ Summary of data presented in the Cell Type Atlas and an interactive image showing mRNA expression in cell type groups e.g. epithelial cells and germ cells. The image is clickable and will redirect to more Cell Type Atlas data. The Cell Type Atlas contains information about single cell type RNA expression based on scRNAseq of human tissues. The data also covers transcriptomics analysis of human blood and cultured cell lines. Read more

Cell type specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed cell types based on scRNA-seq data from normal tissues. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Cell line specificityⁱ RNA specificity category based on RNA sequencing data from all cell lines in the Human Protein Atlas. Genes are classified into six different categories (enriched, group enriched, enhanced, low specificity and not detected) according to their RNA expression levels across the panel of cell lines.	Low cell line specificity

PATHOLOGY ATLASⁱ Summary of data presented in the Pathology Atlas , with representative images of protein expression in cancer (left) and correlation between mRNA expression and patient survival (right). Images are clickable and redirect to pages with more Pathology Atlas data. The Pathology Atlas contains mRNA and protein expression data from 17 different forms of human cancer, as well as correlation analysis of mRNA expression and patient survival. The protein expression data is derived from antibody-based protein profiling using immunohistochemistry. Read more
	Colorectal cancer p<0.001
Prognostic summary	Prognostic marker in colorectal cancer (favorable)
Cancer specificity (RNA)ⁱ Specificity of RNA expression in 17 cancer types is categorized as either cancer enriched, group enriched, cancer enhanced, low cancer specificity and not detected. Read more	Low cancer specificity
Cancer distribution (RNA)ⁱ Distribution of RNA expression in 17 cancer types is categorized as either detected in single, detected in some, detected in many, detected in all, or not detected. Read more	Detected in all

BRAIN ATLASⁱ Summary of data presented in the Brain Atlas and a representative image of mRNA expression in the human brain. The image is clickable and will redirect to more Brain Atlas data. The Brain Atlas explores the protein expression in the mammalian brain by visualization and integration of data from three mammalian species (human, pig and mouse). Transcriptomics data combined with affinity-based protein in situ localization down to single cell level is available in a brain-centric sub atlas of the Human Protein Atlas. Read more

Human regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity
Pig regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity
Mouse regional specificityⁱ The regional specificity category is based on mRNA expression levels in the analyzed brain samples, grouped into 10 main brain regions and calculated for the three different species. The human brain expression profile is based on a combination of data from GTEX and FANTOM5. The specificity categories include: regionally enriched, group enriched, regionally enhanced, low regional specificity and not detected. The classification rules are the same used for the tissue specificity category. Read more	Low region specificity

BLOOD ATLASⁱ Summary of data presented in the Blood Atlas and a representative image of mRNA expression in immune cells in the blood. The image is clickable and will redirect to more Blood Atlas data. The Blood Atlas contains single cell type RNA information covering various immune cells in the blood, e.g. B-cells and granulocytes. Analysis of the human secretome (including annotation of the genes predicted to be actively secreted to human blood) and proteins detected in human blood are also presented. Read more

Immune cell specificityⁱ The RNA specificity category is based on mRNA expression levels in the analyzed samples based on data from HPA. The categories include: cell type enriched, group enriched, cell type enhanced, low cell type specificity and not detected. Read more	Low cell type specificity
Detected in blood by immunoassayⁱ The blood-based immunoassay category applies to actively secreted proteins and is based on plasma or serum protein concentrations established with enzyme-linked immunosorbent assays, compiled from a literature search. The categories include: detected and not detected, where detection refers to a concentration found in the literature search. Read more	No (not applicable)
Detected in blood by mass spectrometryⁱ Detection or not of the gene in blood, based on spectral count estimations from a publicly available mass spectrometry-based plasma proteomics data set obtained from the PeptideAtlas.	Yes

CELL ATLASⁱ Summary of data presented in the Cell Atlas and a representative image of subcellular localization. The Cell Atlas provides RNA expression data derived from RNA sequencing of a large panel of cell lines and protein localization data derived from antibody-based profiling by immunofluorescence confocal microscopy, using a subset of cell lines selected based on RNA expression. Read more

Main locationⁱ Main subcellular location(s) and reliability score(s) for the encoded protein(s) in human cells. The main location(s) may be characterized by presence in all tested cell lines and/or ihigher staining intensity compared to the potential additional location(s). If available, links to overrepresentation analyses in Reactome, a free, open-source, curated and peer reviewed biological pathway database, are provided. An analysis is done for the corresponding gene set of the proteome localizing to the main and additional locations of the protein on this page, respectively. Read more	Localized to the Nucleoplasm, Nucleoli
Cell cycle dependencyⁱ Cell-cycle dependance of single-cell varations in RNA and/or protein expression as observed in an additional assay for characterizing single-cell varations. "NA" indicates a lack of such data. Read more	Variation in protein and transcript expression do not correlate to the cell-cycle.

GENE INFORMATIONⁱ Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	DDX5 (HGNC Symbol)
Synonyms	G17P1, HLR1, p68
Description	DEAD-box helicase 5 (HGNC Symbol)
Chromosome	17
Cytoband	q23.3
Chromosome location (bp)	64499616 - 64508199
Number of transcriptsⁱ Number of protein-coding transcripts from the gene as defined by Ensembl.	16
Protein evidence	Evidence at protein level (all genes)
Protein classⁱ Assigned HPA protein class(es) for the encoded protein(s). Read more	Cancer-related genes Enzymes Plasma proteins
Ensembl	ENSG00000108654 (version 92.38)
Entrez gene	1655
UniProt	P17844 (UniProt - Evidence at protein level)
neXtProt	NX_P17844
Antibodypedia	DDX5 antibodies

PROTEIN BROWSERⁱ

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PROTEIN INFORMATIONⁱ The protein information section displays alternative protein-coding transcripts (splice variants) encoded by this gene according to the Ensembl database. The ENSP identifier links to the Ensembl website protein summary, while the ENST identifier links to the Ensembl website transcript summary for the selected splice variant. The data in the UniProt column can be expanded to show links to all matching UniProt identifiers for this protein. The protein classes assigned to this protein are shown if expanding the data in the protein class column. Parent protein classes are in bold font and subclasses are listed under the parent class. The Gene Ontology terms assigned to this protein are listed if expanding the Gene ontology column. The length of the protein (amino acid residues according to Ensembl), molecular mass (kDalton), predicted signal peptide (according to a majority of the signal peptide predictors SPOCTOPUS, SignalP 4.0, and Phobius) and the number of predicted transmembrane region(s) (according to MDM) are also reported.
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DDX5-201 ENSP00000225792 ENST00000225792	P17844 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000166 [nucleotide binding] GO:0000380 [alternative mRNA splicing, via spliceosome] GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000398 [mRNA splicing, via spliceosome] GO:0000956 [nuclear-transcribed mRNA catabolic process] GO:0001837 [epithelial to mesenchymal transition] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003724 [RNA helicase activity] GO:0003730 [mRNA 3'-UTR binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0004386 [helicase activity] GO:0005515 [protein binding] GO:0005516 [calmodulin binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005681 [spliceosomal complex] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0009299 [mRNA transcription] GO:0010501 [RNA secondary structure unwinding] GO:0016020 [membrane] GO:0016049 [cell growth] GO:0016787 [hydrolase activity] GO:0019899 [enzyme binding] GO:0030509 [BMP signaling pathway] GO:0030520 [intracellular estrogen receptor signaling pathway] GO:0030521 [androgen receptor signaling pathway] GO:0030529 [intracellular ribonucleoprotein complex] GO:0035500 [MH2 domain binding] GO:0036002 [pre-mRNA binding] GO:0043021 [ribonucleoprotein complex binding] GO:0043517 [positive regulation of DNA damage response, signal transduction by p53 class mediator] GO:0045069 [regulation of viral genome replication] GO:0045445 [myoblast differentiation] GO:0045667 [regulation of osteoblast differentiation] GO:0046332 [SMAD binding] GO:0048306 [calcium-dependent protein binding] GO:0048511 [rhythmic process] GO:0050681 [androgen receptor binding] GO:0060765 [regulation of androgen receptor signaling pathway] GO:0061614 [pri-miRNA transcription from RNA polymerase II promoter] GO:0070062 [extracellular exosome] GO:0070412 [R-SMAD binding] GO:0070878 [primary miRNA binding] GO:0071013 [catalytic step 2 spliceosome] GO:0071141 [SMAD protein complex] GO:0072332 [intrinsic apoptotic signaling pathway by p53 class mediator] GO:1903800 [positive regulation of production of miRNAs involved in gene silencing by miRNA] GO:1990841 [promoter-specific chromatin binding] GO:2001014 [regulation of skeletal muscle cell differentiation] Show all	614 aa 69.1 kDa	No	0
DDX5-202 ENSP00000403085 ENST00000450599	P17844 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Enzymes ENZYME proteins Hydrolases Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Plasma proteins Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Mapped to neXtProt neXtProt - Evidence at protein level Protein evidence (Peptideatlas) Show all	GO:0000122 [negative regulation of transcription from RNA polymerase II promoter] GO:0000166 [nucleotide binding] GO:0000380 [alternative mRNA splicing, via spliceosome] GO:0000381 [regulation of alternative mRNA splicing, via spliceosome] GO:0000398 [mRNA splicing, via spliceosome] GO:0000956 [nuclear-transcribed mRNA catabolic process] GO:0001837 [epithelial to mesenchymal transition] GO:0003676 [nucleic acid binding] GO:0003723 [RNA binding] GO:0003724 [RNA helicase activity] GO:0003730 [mRNA 3'-UTR binding] GO:0004004 [ATP-dependent RNA helicase activity] GO:0004386 [helicase activity] GO:0005515 [protein binding] GO:0005524 [ATP binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005681 [spliceosomal complex] GO:0005730 [nucleolus] GO:0005737 [cytoplasm] GO:0006351 [transcription, DNA-templated] GO:0006355 [regulation of transcription, DNA-templated] GO:0006357 [regulation of transcription from RNA polymerase II promoter] GO:0006397 [mRNA processing] GO:0008380 [RNA splicing] GO:0009299 [mRNA transcription] GO:0010501 [RNA secondary structure unwinding] GO:0016020 [membrane] GO:0016049 [cell growth] GO:0016787 [hydrolase activity] GO:0030509 [BMP signaling pathway] GO:0030520 [intracellular estrogen receptor signaling pathway] GO:0030521 [androgen receptor signaling pathway] GO:0030529 [intracellular ribonucleoprotein complex] GO:0035500 [MH2 domain binding] GO:0036002 [pre-mRNA binding] GO:0043021 [ribonucleoprotein complex binding] GO:0043517 [positive regulation of DNA damage response, signal transduction by p53 class mediator] GO:0045445 [myoblast differentiation] GO:0045667 [regulation of osteoblast differentiation] GO:0046332 [SMAD binding] GO:0048511 [rhythmic process] GO:0050681 [androgen receptor binding] GO:0060765 [regulation of androgen receptor signaling pathway] GO:0061614 [pri-miRNA transcription from RNA polymerase II promoter] GO:0070062 [extracellular exosome] GO:0070412 [R-SMAD binding] GO:0070878 [primary miRNA binding] GO:0071013 [catalytic step 2 spliceosome] GO:0071141 [SMAD protein complex] GO:0072332 [intrinsic apoptotic signaling pathway by p53 class mediator] GO:1903800 [positive regulation of production of miRNAs involved in gene silencing by miRNA] GO:1990841 [promoter-specific chromatin binding] GO:2001014 [regulation of skeletal muscle cell differentiation] Show all	535 aa 60.6 kDa	No	0
DDX5-204 ENSP00000462222 ENST00000577787	J3KRZ1 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0003676 [nucleic acid binding] GO:0005524 [ATP binding] Show all	166 aa 18.9 kDa	No	0
DDX5-205 ENSP00000464337 ENST00000577922	J3QRQ7 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0003676 [nucleic acid binding] GO:0005524 [ATP binding] Show all	212 aa 23.5 kDa	No	0
DDX5-206 ENSP00000463541 ENST00000578190	J3QLG9 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0003676 [nucleic acid binding] GO:0005524 [ATP binding] Show all	46 aa 4.8 kDa	No	0
DDX5-210 ENSP00000462885 ENST00000578804	J3KTA4 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0000166 [nucleotide binding] GO:0003676 [nucleic acid binding] GO:0004386 [helicase activity] GO:0005524 [ATP binding] GO:0016787 [hydrolase activity] Show all	614 aa 69.1 kDa	No	0
DDX5-211 ENSP00000464587 ENST00000579091	J3QS97 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all		31 aa 3.3 kDa	No	0
DDX5-213 ENSP00000464659 ENST00000579996	J3QSF1 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0003676 [nucleic acid binding] GO:0005524 [ATP binding] Show all	153 aa 17.9 kDa	No	0
DDX5-219 ENSP00000464304 ENST00000581697	J3QRN5 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0003676 [nucleic acid binding] GO:0005524 [ATP binding] Show all	65 aa 6.9 kDa	No	0
DDX5-220 ENSP00000464064 ENST00000581806	J3QR62 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all	GO:0003676 [nucleic acid binding] GO:0005524 [ATP binding] Show all	52 aa 5.5 kDa	No	0
DDX5-223 ENSP00000463903 ENST00000583212	A0A0G2JLI4 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all		10 aa 1.2 kDa	No	0
DDX5-224 ENSP00000463101 ENST00000583239	J3KTQ4 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all		181 aa 19.8 kDa	No	0
DDX5-228 ENSP00000462206 ENST00000584279	J3KRX8 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all		120 aa 13.7 kDa	No	0
DDX5-231 ENSP00000465791 ENST00000585060	K7EKV0 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all		16 aa 1.8 kDa	No	0
DDX5-232 ENSP00000463168 ENST00000585111	J3QKN9 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all		44 aa 4.7 kDa	No	0
DDX5-235 ENSP00000485764 ENST00000630471	J3QR02 [Direct mapping] Probable ATP-dependent RNA helicase DDX5 Show all	Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Cancer-related genes Mutated cancer genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Show all		99 aa 11.4 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
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