ALOX12

GENERAL INFORMATION

? »

Gene name

ALOX12

Gene description

Arachidonate 12-lipoxygenase

Protein class

Disease related genes
Enzymes
Potential drug targets
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Group enriched (esophagus, skin)
GTEx:Tissue enhanced (cervix, uterine, vagina)

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in most cell types. High expression level in myocytes.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Supportive based on 2 antibodies.
HPA010691 , CAB019287
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

Skin



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Group enriched (esophagus, skin)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cervix, uterine, vagina)

Organ

Expression



GENE INFORMATION

? »

Gene name

ALOX12 (HGNC Symbol)

Synonyms

12S-LOX

Description

Arachidonate 12-lipoxygenase (HGNC Symbol)

Entrez gene summary

Chromosome

17

Cytoband

p13.1

Chromosome location (bp)

6996065 - 7010736

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000108839 (version 78.38)

Entrez gene

239

UniProt

P18054 (UniProt - Evidence at protein level)

neXtProt

NX_P18054

Antibodypedia

ALOX12 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000251535
 
ENST00000480801
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALOX12-001 ENSP00000251535
ENST00000251535
P18054
Show all »
Show » Show » 663 75.7 No 0
ALOX12-003 ENSP00000467033
ENST00000480801
K7ENN9
Show all »
Show » Show » 147 16.9 No 0