VIPR1

GENERAL INFORMATION

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Gene name

VIPR1

Gene description

Vasoactive intestinal peptide receptor 1

Protein class

G-protein coupled receptors
Predicted membrane proteins
Transporters

Predicted localization

Membrane

Number of transcripts

6
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (lung)
GTEx:Tissue enhanced (lung)

Protein evidence

Evidence at protein level

Protein localization

Most normal tissues showed moderate cytoplasmic staining and membranous positivity. Skeletal muscle, prostate, adrenal gland and salivary gland displayed strong immunoreactivity.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA026777
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Skeletal muscle

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (lung)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (lung)

Organ

Expression



GENE INFORMATION

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Gene name

VIPR1 (HGNC Symbol)

Synonyms

HVR1, RDC1, VPAC1, VPAC1R

Description

Vasoactive intestinal peptide receptor 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Chromosome

3

Cytoband

p22.1

Chromosome location (bp)

42489299 - 42537573

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000114812 (version 78.38)

Entrez gene

7433

UniProt

P32241 (UniProt - Evidence at protein level)

neXtProt

NX_P32241

Antibodypedia

VIPR1 antibodies


PROTEIN BROWSER

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ENST00000325123
 
ENST00000433647
 
ENST00000438259
 
ENST00000439731
 
ENST00000450274
 
ENST00000543411
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VIPR1-001 ENSP00000327246
ENST00000325123
P32241
Show all »
Show » Show » 457 51.5 Yes 7
VIPR1-002 ENSP00000394950
ENST00000433647
P32241
Show all »
Show » Show » 416 47.2 No 7
VIPR1-011 ENSP00000415013
ENST00000450274
C9JH33
Show all »
Show » Show » 126 13.8 No 1
VIPR1-013 ENSP00000403478
ENST00000439731
C9JDT8
Show all »
Show » Show » 219 23.7 Yes 1
VIPR1-201 ENSP00000415371
ENST00000438259
P32241
Show all »
Show » Show » 247 28.2 No 4
VIPR1-202 ENSP00000445701
ENST00000543411
P32241
Show all »
Show » Show » 409 46.3 No 7