STK25

GENERAL INFORMATION

? »

Gene name

STK25

Gene description

Serine/threonine kinase 25

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

19
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests general expression, highest level in skeletal muscle. RNA-based expert annotation could not be performed.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA047147
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »
RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

? »

Gene name

STK25 (HGNC Symbol)

Synonyms

SOK1, YSK1

Description

Serine/threonine kinase 25 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the germinal centre kinase III (GCK III) subfamily of the sterile 20 superfamily of kinases. The encoded enzyme plays a role in serine-threonine liver kinase B1 (LKB1) signaling pathway to regulate neuronal polarization and morphology of the Golgi apparatus. The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death. A pseudogene associated with this gene is located on chromosome 18. Multiple alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2012]

Chromosome

2

Cytoband

q37.3

Chromosome location (bp)

241492674 - 241509730

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000115694 (version 78.38)

Entrez gene

10494

UniProt

O00506 (UniProt - Evidence at protein level)

neXtProt

NX_O00506

Antibodypedia

STK25 antibodies


PROTEIN BROWSER

? »
 
 
 « 
 
ENST00000316586
 
ENST00000401869
 
ENST00000403346
 
ENST00000405585
 
ENST00000405883
 
ENST00000413760
 
ENST00000420551
 
ENST00000423004
 
ENST00000424537
 
ENST00000426941
 
ENST00000429279
 
ENST00000435225
 
ENST00000436402
 
ENST00000439101
 
ENST00000440109
 
ENST00000442307
 
ENST00000450497
 
ENST00000535007
 
ENST00000543554
 
 » 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

STK25-001 ENSP00000325748
ENST00000316586
O00506
Show all »
Show » Show » 426 48.1 No 0
STK25-002 ENSP00000384162
ENST00000403346
O00506
Show all »
Show » Show » 426 48.1 No 0
STK25-003 ENSP00000385541
ENST00000405585
O00506
Show all »
Show » Show » 349 39.3 No 0
STK25-004 ENSP00000384444
ENST00000405883
O00506
Show all »
Show » Show » 349 39.3 No 0
STK25-005 ENSP00000385687
ENST00000401869
O00506
Show all »
Show » Show » 426 48.1 No 0
STK25-007 ENSP00000403607
ENST00000442307
C9JCC0
Show all »
Show » Show » 163 18.2 No 0
STK25-009 ENSP00000404960
ENST00000429279
C9JJV0
Show all »
Show » Show » 79 8.7 No 0
STK25-010 ENSP00000404552
ENST00000420551
C9JFA1
Show all »
Show » Show » 89 10 No 0
STK25-014 ENSP00000414191
ENST00000426941
C9JN58
Show all »
Show » Show » 115 13 No 0
STK25-016 ENSP00000417020
ENST00000424537
C9J6L2
Show all »
Show » Show » 161 18.1 No 0
STK25-017 ENSP00000406208
ENST00000439101
Show » 19 2 No 0
STK25-018 ENSP00000403866
ENST00000440109
C9JIH8
Show all »
Show » Show » 58 6.2 No 0
STK25-019 ENSP00000401114
ENST00000435225
C9K0M6
Show all »
Show » Show » 49 5.5 No 0
STK25-020 ENSP00000395104
ENST00000413760
C9JDH9
Show all »
Show » Show » 148 16.4 No 0
STK25-023 ENSP00000399212
ENST00000450497
C9J232
Show all »
Show » Show » 177 19.9 No 0
STK25-026 ENSP00000404469
ENST00000423004
Show » Show » 247 27.8 No 0
STK25-033 ENSP00000412617
ENST00000436402
E7EM58
Show all »
Show » Show » 152 17.3 No 0
STK25-201 ENSP00000446008
ENST00000535007
O00506
Show all »
Show » Show » 332 37.3 No 0
STK25-202 ENSP00000444886
ENST00000543554
O00506
Show all »
Show » Show » 332 37.3 No 0