MRPL37

GENERAL INFORMATION

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Gene name

MRPL37

Gene description

Mitochondrial ribosomal protein L37

Protein class

Mitochondrial proteins
Predicted intracellular proteins
Ribosomal proteins

Predicted localization

Intracellular

Number of transcripts

4
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous cytoplasmic staining with a granular pattern.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 3 antibodies.
HPA025767 , HPA025826 , HPA025951
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

MRPL37 (HGNC Symbol)

Synonyms

MRP-L2, RPML2

Description

Mitochondrial ribosomal protein L37 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]

Chromosome

1

Cytoband

p32.3

Chromosome location (bp)

54184041 - 54225464

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000116221 (version 78.38)

Entrez gene

51253

UniProt

Q9BZE1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9BZE1

Antibodypedia

MRPL37 antibodies


PROTEIN BROWSER

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ENST00000336230
 
ENST00000360840
 
ENST00000398219
 
ENST00000605337
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL37-001 ENSP00000354086
ENST00000360840
Q9BZE1
Show all »
Show » Show » 423 48.1 No 0
MRPL37-003 ENSP00000392216
ENST00000398219
Show » Show » 264 29.5 No 0
MRPL37-005 ENSP00000473980
ENST00000605337
S4R369
Show all »
Show » Show » 483 55 No 0
MRPL37-201 ENSP00000338526
ENST00000336230
A6NHR2
Show all »
Show » Show » 292 32.5 No 0