ZMYM2

GENERAL INFORMATION

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Gene name

ZMYM2

Gene description

Zinc finger, MYM-type 2

Protein class

Cancer-related genes
Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most of the normal tissues displayed moderate nuclear and occasional cytoplasmic positivity. Strong staining was seen in respiratory epithelia, thyroid gland, urothelium, testis and neuronal cells. The lung, liver, glial cells and cells in red pulp of spleen were generally negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA031765
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ZMYM2 (HGNC Symbol)

Synonyms

FIM, MYM, RAMP, ZNF198

Description

Zinc finger, MYM-type 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a zinc finger protein that may act as a transcription factor. The encoded protein may be part of a BHC histone deacetylase complex. Translocation of this gene with the fibroblast growth factor receptor-1 gene (FGFR1) results in a fusion gene, which may be a cause of stem cell leukemia lymphoma syndrome (SCLL). Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

Chromosome

13

Cytoband

q12.11

Chromosome location (bp)

19958670 - 20091829

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000121741 (version 78.38)

Entrez gene

7750

UniProt

Q9UBW7 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UBW7

Antibodypedia

ZMYM2 antibodies


PROTEIN BROWSER

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ENST00000382871
 
ENST00000382874
 
ENST00000610343
 
ENST00000610795
 
ENST00000620447
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZMYM2-003 ENSP00000372327
ENST00000382874
Q9UBW7
Show all »
Show » Show » 1377 154.9 No 0
ZMYM2-005 ENSP00000372324
ENST00000382871
Q9UBW7
Show all »
Show » Show » 1377 154.9 No 0
ZMYM2-010 ENSP00000483904
ENST00000620447
Show » Show » 276 29.8 No 0
ZMYM2-201 ENSP00000479904
ENST00000610343
Q9UBW7
Show all »
Show » Show » 1377 154.9 No 0
ZMYM2-202 ENSP00000477661
ENST00000610795
Q9UBW7
Show all »
Show » Show » 1377 154.9 No 0