CTCFL

GENERAL INFORMATION

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Gene name

CTCFL

Gene description

CCCTC-binding factor (zinc finger protein)-like

Protein class

Predicted intracellular proteins
Predicted membrane proteins
Transcription factors

Predicted localization

Intracellular,Membrane

Number of transcripts

16
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

Nuclear expression in spermatogonia in testis

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data.

Data reliability

Supportive based on 1 antibody.
HPA001472
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

CTCFL (HGNC Symbol)

Synonyms

BORIS, CT27, dJ579F20.2

Description

CCCTC-binding factor (zinc finger protein)-like (HGNC Symbol)

Entrez gene summary

CCCTC-binding factor (CTCF), an 11-zinc-finger factor involved in gene regulation, utilizes different zinc fingers to bind varying DNA target sites. CTCF forms methylation-sensitive insulators that regulate X-chromosome inactivation. This gene is a paralog of CTCF and appears to be expressed primarily in the cytoplasm of spermatocytes, unlike CTCF which is expressed primarily in the nucleus of somatic cells. CTCF and the protein encoded by this gene are normally expressed in a mutually exclusive pattern that correlates with resetting of methylation marks during male germ cell differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

Chromosome

20

Cytoband

q13.31

Chromosome location (bp)

57495966 - 57525652

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000124092 (version 78.38)

Entrez gene

140690

UniProt

Q8NI51 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NI51

Antibodypedia

CTCFL antibodies


PROTEIN BROWSER

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ENST00000243914
 
ENST00000371196
 
ENST00000422869
 
ENST00000423479
 
ENST00000429804
 
ENST00000432255
 
ENST00000433949
 
ENST00000481655
 
ENST00000502686
 
ENST00000539382
 
ENST00000608158
 
ENST00000608263
 
ENST00000608425
 
ENST00000608440
 
ENST00000608903
 
ENST00000609232
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CTCFL-001 ENSP00000243914
ENST00000243914
Q8NI51
Show all »
Show » Show » 663 75.7 No 0
CTCFL-003 ENSP00000360239
ENST00000371196
Q8NI51
Show all »
Show » Show » 663 75.7 No 0
CTCFL-004 ENSP00000476398
ENST00000609232
Q8NI51
Show all »
Show » Show » 663 75.7 No 0
CTCFL-005 ENSP00000415329
ENST00000429804
Q8NI51
Show all »
Show » Show » 613 69.9 No 0
CTCFL-006 ENSP00000409344
ENST00000432255
Q8NI51
Show all »
Show » Show » 483 54.2 No 0
CTCFL-011 ENSP00000477165
ENST00000608158
V9GYX4
Show all »
Show » Show » 404 45.8 No 0
CTCFL-012 ENSP00000476577
ENST00000481655
V9GYX4
Show all »
Show » Show » 404 45.8 No 0
CTCFL-013 ENSP00000439998
ENST00000539382
Q8NI51
Show all »
Show » Show » 422 48.1 No 0
CTCFL-014 ENSP00000476458
ENST00000608425
V9GY73
Show all »
Show » Show » 627 71.2 No 0
CTCFL-015 ENSP00000476718
ENST00000608903
Q8NI51
Show all »
Show » Show » 299 35.4 No 0
CTCFL-016 ENSP00000399061
ENST00000422869
Q8NI51
Show all »
Show » Show » 573 66 No 0
CTCFL-019 ENSP00000476783
ENST00000608263
Q8NI51
Show all »
Show » Show » 663 75.7 No 0
CTCFL-020 ENSP00000415579
ENST00000423479
Q8NI51
Show all »
Show » Show » 700 80 No 0
CTCFL-021 ENSP00000392034
ENST00000433949
Q8NI51
Show all »
Show » Show » 460 52.7 No 1
CTCFL-022 ENSP00000437999
ENST00000502686
Q8NI51
Show all »
Show » Show » 403 46.5 No 1
CTCFL-023 ENSP00000477488
ENST00000608440
Q8NI51
Show all »
Show » Show » 665 75.8 No 1