Fields »

SUBCELLULAR LOCATION

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Main location(s)

Cytoplasm, Mitochondria

Additional location(s)

 

Staining summary

Localized to cytoplasm and mitochondria.

Reliability (APE)

High

Antibodies in assay

HPA004895, CAB013018
 

Antibody HPA004895

 

Antibody CAB013018

 

         Cell line A-431

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Location(s)

Cytoplasm Cytoplasm, Mitochondria 

Staining characteristics

Granular  

Staining intensity

Moderate Moderate 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

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Location(s)

Cytoplasm   

Staining characteristics

Granular   

Staining intensity

Weak   

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
   

Comment

   

         Cell line U-251 MG

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Location(s)

Cytoplasm Cytoplasm, Mitochondria 

Staining characteristics

  

Staining intensity

Moderate Moderate 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in cytoplasm.
 

Immunofluorescent staining of human cell line U-251 MG shows positivity in cytoplasm & mitochondria.
 

Summary

Staining of cytoplasm in all three cell lines.   Staining of cytoplasm and mitochondria in A-431 and U-251 MG.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is supported by literature.
 

Dictionary

Cytoplasm
Mitochondria